| Year | Title | Role | Notes |
|---|
| 1983 | Svengali | Leslie | Television film |
| An Uncommon Love | Karen |
| 1984 | With Intent to Kill | Wynn Nolen |
| 1987 | A Gathering of Old Men | Candy Marshall |
| 1989 | Roe vs. Wade | Ellen Russell/Jane Doe |
| The Three Billy Goats Gruff and The Three Little Pigs | Narrator (voice) | Television short |
| 1992 | Crazy in Love | Georgie Symonds | Television film |
| 1993 | The Positively True Adventures of the Alleged Texas Cheerleader-Murdering Mom | Wanda Holloway |
| 2000 | Harlan County War | Ruby Kincaid |
| Things You Can Tell Just by Looking at Her | Rebecca Weyman | Segment: "Fantasies About Rebecca" |
| 2001 | When Billie Beat Bobby | Billie Jean King | Television film; also executive producer |
| 2007 | Peep and the Big Wide World | Robin (voice) | Episode: "Big Bird/Chirp Flies the Coop" |
| 2007–2010 | Saving Grace | Grace Hanadarko | 46 episodes; also executive producer |
| 2013 | Top of the Lake | GJ | 6 episodes |
| Bonnie & Clyde | Emma Parker | 2 episodes |
| 2018 | Here and Now | Audrey Bayer | 10 episodes |
| 2019 | Succession | Rhea Jarrell | 6 episodes |
| 2019–2020 | Bless the Harts | Marjune Gamble (voice) | 3 episodes |
| 2020 | The Comey Rule | Sally Yates | 2 episodes |
| 2021–2022 | Mr. Mayor | Arpi Meskimen | Main role |
| 2024 | Mulligan | Sheila (voice) | 2 episodes |
| 2025 | Big Mouth | Coco the Compassion Pachyderm (voice) | Episode: "Have Some Goddamn Compassion" |
| 2026 | Star Trek: Starfleet Academy[1] | Captain Nahla Ake | Upcoming series |
