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维基百科自由的百科全书
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芳基环己胺

维基百科，自由的百科全书
苯环己哌啶，最常见的芳基环己胺衍生物

芳基环己胺衍生物（英語：Arylcyclohexylamine、arylcyclohexamines或arylcyclohexanamines）是一类含氮有机化合物，常用作药品和狡詐家藥物和试验药物，其特点是环己烷的一个碳原子上连接了氨基的N原子和芳香基，常见的有乙环利定、苯环己哌啶等[1]。

芳基环己胺的各个取代基
从左至右依次是4-甲基-PCP、4'-甲基-PCP、4''-甲基-PCP

化合物

[编辑]
结构化合物分子式芳香基团含N取代基环己烷侧取代基CAS编号
PCA[2]C12H17N苯基NH2-1934-71-0
PCM[2]C13H19N苯基甲氨基-2201-16-3
乙环利定（PCE）C14H21N苯基乙氨基-2201-15-2
PCPr[3]C15H23N苯基正丙氨基-18949-81-0
PCiPC15H23N苯基异丙氨基-1195-42-2
PCAL[4]C15H21N苯基烯丙氨基-2185-95-7
PCBuC16H25N苯基正丁氨基-73166-29-7
PCEOHC14H21NO苯基羟乙氨基-2201-22-1
PCMEA[5]C15H23NO苯基甲氧乙氨基-2201-57-2
PCEEAC16H25NO苯基乙氧乙氨基-1072895-05-6
PCMPAC16H25NO苯基甲氧丙氨基-2201-58-3
PCDM[2]C14H21N苯基二甲氨基-2201-17-4
二乙环利定（英语：Dieticyclidine）（PCDE）C16H25N苯基二乙氨基-2201-19-6
2-HO-PCP[6]C17H25NO苯基哌啶基2-羟基94852-58-1
2-Me-PCP[7]C18H27N苯基哌啶基2-甲基59397-29-4
2-MeO-PCP[8]C18H27NO苯基哌啶基2-甲氧基78636-34-7
2-Keto-PCPC17H23NO苯基哌啶基2-酮101688-16-8
2-氧代-PCE（"O-PCE"）C14H19NO苯基乙氨基2-酮6740-82-5
2-Keto-PCPrC15H21NO苯基正丙氨基2-酮
4-Methyl-PCPC18H27N苯基哌啶基4-甲基19420-52-1
4-Keto-PCP[9]C17H23NO苯基哌啶基4-酮65620-13-5
2'-Cl-PCPC17H24ClN邻氯苯基哌啶基-2201-31-2
3'-Cl-PCPC17H24ClN间氯苯基哌啶基-2201-32-3
2'-MeO-PCPC18H27NO邻甲氧基苯基哌啶基-2201-34-5
3'-F-PCP[10]C17H24FN间氟苯基哌啶基-89156-99-0
3-甲基苯环己哌啶（3'-Me-PCP）[11]C18H27N间甲苯基哌啶基-2201-30-1
3'-Me-PCPyC17H25N间甲苯基吡咯基-1622348-63-3
3'-NH2-PCPC17H26N2间氨基苯基哌啶基-72242-00-3
3-羥基苯環己哌啶（3'-HO-PCP）C17H25NO间羟基苯基哌啶基-79787-43-2
3-甲氧基苯環己哌啶（3'-MeO-PCP）C18H27NO间甲氧基苯基哌啶基-72242-03-6
3',4'-MD-PCPC18H25NO23,4-亚甲二氧基苯基哌啶基-
3'-MeO-PCEC15H23NO间甲氧基苯基乙氨基-1364933-80-1
3'-HO-PCE间羟基苯基乙氨基-
3'-MeO-PCPr间甲氧基苯基正丙氨基-1364933-81-2
3'-HO-PCPr间羟基苯基正丙氨基-
3',4'-MD-PCPr3,4-亚甲二氧基苯基正丙氨基-
3'-MeO-PCPy[11]间甲氧基苯基吡咯基-1364933-79-8
4-羥基苯環己哌啶（4'-HO-PCP）C17H25NO对羟基苯基哌啶基-66568-88-5
4-甲氧基苯環己哌啶（4'-MeO-PCP）C18H27NO对甲氧基苯基哌啶基-2201-35-6
4'-MeO-PCEC15H23NO对甲氧基苯基乙氨基-
4'-F-PCP[10]p-Fluorophenyl哌啶基-22904-99-0
4'-F-PCPyp-Fluorophenyl吡咯基-
ArketamineC13H16ClNO邻氯苯基甲氨基2-酮33643-49-1
2-苯基-2-甲氨基环己酮C13H17NO苯基甲氨基2-酮7063-30-1
EsketamineC13H16ClNO邻氯苯基甲氨基2-酮33643-46-8
氯胺酮C13H16ClNO邻氯苯基甲氨基2-酮6740-88-1
HydroxynorketamineC12H14ClNO2邻氯苯基NH22-酮,6-羟基81395-70-2
EthketamineC14H18ClNO邻氯苯基乙氨基2-酮1354634-10-8
NPNKC15H20ClNO邻氯苯基正丙氨基2-酮2749326-65-4
MethoxyketamineC14H19NO2邻甲氧基苯基甲氨基2-酮7063-51-6
2-MeO-NEK[12]C15H21NO2邻甲氧基苯基乙氨基2-酮
oMDCK[13]C14H19NO邻甲苯基甲氨基2-酮7063-37-8
mMDCKC14H19NO间甲苯基甲氨基2-酮
meta-KetamineC13H16ClNO间氯苯基甲氨基2-酮7063-53-8
iso-KetamineC13H16ClNO邻氯苯基甲氨基4-酮
氟胺酮C13H16FNO邻氟苯基甲氨基2-酮111982-50-4
3-氟脱氯氯胺酮C13H16FNO间氟苯基甲氨基2-酮2657761-23-2
Bromoketamine邻溴苯基甲氨基2-酮120807-70-7
TFMDCKo-Trifluoromethylphenyl甲氨基2-酮1782149-73-8
SN 35210[14]邻氯苯基Carbomethoxybutylamino2-酮1450615-41-4
MethoxetamineC15H21NO2间甲氧基苯基乙氨基2-酮1239943-76-0
MethoxmetamineC14H19NO2间甲氧基苯基甲氨基2-酮1781829-56-8
MethoxpropamineC16H23NO2间甲氧基苯基正丙氨基2-酮2504100-71-2
MXiPrC16H23NO2间甲氧基苯基异丙氨基2-酮
EthoxetamineC16H23NO2间乙氧基苯基乙氨基2-酮
2-乙氨基-2-(3-甲基苯基)环己酮（英语：Deoxymethoxetamine）（DMXE、3-Me-2'-Oxo-PCE）C15H21NO间甲苯基乙氨基2-酮2666932-45-0
Br-MXE2-溴-5-甲氧基苯基乙氨基2-酮
Hydroxetamine (HXE)间羟基苯基乙氨基2-酮1620054-73-0
HXM间羟基苯基甲氨基2-酮
2F-NENDCK（英语：2F-NENDCK）C14H18FNO邻氟苯基乙氨基2-酮
Fluorexetamine（英语：Fluorexetamine） (FXE)C14H18FNO间氟苯基乙氨基2-酮
苯环己哌啶（PCP）C17H25N苯基哌啶基-77-10-1
PC3MPC18H27N苯基3-甲基哌啶基-2201-41-4
PC4MPC18H27N苯基4-甲基哌啶基-2201-42-5
咯环利定（英语：Rolicyclidine）（PCPy）C16H23N苯基吡咯基-2201-39-0
PCDMPyC18H27N苯基3,3-二甲基吡咯基-
PCMoC16H23NO苯基吗啉基-2201-40-3
Methoxy-PCM[15] (2'-MeO-PCMo)邻甲氧基苯基Morpholine-1314323-88-0
3'-MeO-PCMo间甲氧基苯基Morpholine-138873-80-0
4'-MeO-PCMo对间甲氧基苯基Morpholine-
Methyl-PCM[16] (4'-Me-PCMo)对甲苯基Morpholine-120803-52-3
Hydroxy-methyl-PCM2-Methyl-4-hydroxyphenylMorpholine-1314323-89-1
PYCP[17]2-Pyridinyl哌啶基-
TCM2-噻吩基甲氨基-139401-07-3
TCE2-噻吩基乙氨基-101589-62-2
TCPr[18]2-噻吩基正丙氨基-
Tenocyclidine (TCP)2-噻吩基哌啶基-21500-98-1
T3CP3-噻吩基哌啶基-19420-50-9
TCPy2-噻吩基吡咯基-22912-13-6
Tiletamine2-噻吩基乙氨基2-酮14176-49-9
MXTE4-Methoxy-2-thienyl乙氨基2-酮
Gacyclidine2-噻吩基哌啶基2-Methyl68134-81-6
BDPCp-BromophenylDimethylamino4-Phenethyl-4-hydroxy77239-98-6
C-8813p-BromophenylDimethylamino4-(thiophen-2-yl)ethyl-4-hydroxy616898-54-5
Dimetamine[19]对甲苯基Dimethylamino4-酮65619-06-9
3''-OH-2'-Me-PCP[20]C18H27NO邻甲苯基3-Hydroxypiperidine-
4''-Ph-4''-OH-PCP[21]苯基4-Phenyl-4-hydroxypiperidine-77179-39-6
BTCP[22]Benzothiophen-2-yl哌啶基-112726-66-6
BTCPy[23]Benzothiophen-2-yl吡咯基-
GK-189[24]Naphthalen-2-yl哌啶基-81490-58-6

参考文献

[编辑]
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