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5-hydroxytryptamine receptor 2B
(Q4639596)
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From Wikidata
mammalian protein found in Homo sapiens
5-HT 2B receptor
serotonin receptor 2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
5-hydroxytryptamine 2B receptor
HTR2B
5-hydroxytryptamine receptor 2B variant b
edit
Language
Label
Description
Also known as
default for all languages
No label defined
–
English
5-hydroxytryptamine receptor 2B
mammalian protein found in Homo sapiens
5-HT 2B receptor
serotonin receptor 2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
5-hydroxytryptamine 2B receptor
HTR2B
5-hydroxytryptamine receptor 2B variant b
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P41595
part of
5-hydroxytryptamine 2B receptor
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P41595
G protein-coupled recepteishon
1 reference
Transporter Classification Database ID
9.A.14.3.7
retrieved
2 October 2019
based on heuristic
hierarchical database ID heuristic
GPCR, rhodopsin-like, 7TM, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P41595
encoded by
HTR2B
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P41595
molecular function
G protein-coupled receptor activity
determination method or standard
IEA
2 references
retrieved
21 June 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P41595&geneProductId=UniProtKB:P41595
determination method or standard
IEA
retrieved
21 June 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P41595&geneProductId=UniProtKB:P41595
determination method or standard
IEA
GTPase activator activity
determination method or standard
ISS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
ISS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
signal transducer activity
determination method or standard
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P41595&geneProductId=UniProtKB:P41595
determination method or standard
IEA
G protein-coupled serotonin receptor activity
determination method or standard
IDA
IEA
5 references
retrieved
21 June 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P41595&geneProductId=UniProtKB:P41595
determination method or standard
IEA
retrieved
21 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P41595&geneProductId=UniProtKB:P41595
determination method or standard
IEA
retrieved
21 June 2018
stated in
Molecular and pharmacological characterization of serotonin 5-HT2A and 5-HT2B receptor subtypes in dog
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P41595&geneProductId=UniProtKB:P41595
determination method or standard
IDA
retrieved
21 June 2018
stated in
The human serotonin 5-HT2B receptor: pharmacological link between 5-HT2 and 5-HT1D receptors
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P41595&geneProductId=UniProtKB:P41595
determination method or standard
IDA
retrieved
21 June 2018
stated in
The pharmacology and distribution of human 5‐hydroxytryptamine2B (5‐HT2b) receptor gene products: comparison with 5‐HT2a and 5‐HT2c receptors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P41595&geneProductId=UniProtKB:P41595
determination method or standard
IDA
G-protein alpha-subunit binding
determination method or standard
IMP
1 reference
retrieved
8 April 2019
stated in
The natural mutation encoding a C terminus-truncated 5-hydroxytryptamine 2B receptor is a gain of proliferative functions
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IMP
serotonin binding
determination method or standard
IDA
IEA
8 references
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
retrieved
8 April 2019
stated in
The human serotonin 5-HT2B receptor: pharmacological link between 5-HT2 and 5-HT1D receptors
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IDA
retrieved
8 April 2019
stated in
The natural mutation encoding a C terminus-truncated 5-hydroxytryptamine 2B receptor is a gain of proliferative functions
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IDA
retrieved
8 April 2019
stated in
Pharmacological characterization of mitogen-activated protein kinase activation by recombinant human 5-HT2C, 5-HT2A, and 5-HT2B receptors
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IDA
retrieved
8 April 2019
stated in
Molecular determinants for the interaction of the valvulopathic anorexigen norfenfluramine with the 5-HT2B receptor
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IDA
retrieved
8 April 2019
stated in
Molecular and pharmacological characterization of serotonin 5-HT2A and 5-HT2B receptor subtypes in dog
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IDA
retrieved
8 April 2019
stated in
Identification of a key amino acid of the human 5-HT(2B) serotonin receptor important for sarpogrelate binding
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IDA
retrieved
8 April 2019
stated in
The pharmacology and distribution of human 5‐hydroxytryptamine2B (5‐HT2b) receptor gene products: comparison with 5‐HT2a and 5‐HT2c receptors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IDA
neurotransmitter receptor activity
determination method or standard
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IBA
G protein-coupled receptor activity
determination method or standard
IBA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IBA
G protein-coupled serotonin receptor activity
determination method or standard
IBA
IDA
IEA
6 references
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
retrieved
8 April 2019
stated in
Molecular and pharmacological characterization of serotonin 5-HT2A and 5-HT2B receptor subtypes in dog
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IDA
retrieved
8 April 2019
stated in
The human serotonin 5-HT2B receptor: pharmacological link between 5-HT2 and 5-HT1D receptors
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IDA
retrieved
8 April 2019
stated in
The pharmacology and distribution of human 5‐hydroxytryptamine2B (5‐HT2b) receptor gene products: comparison with 5‐HT2a and 5‐HT2c receptors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IBA
cell component
cytoplasm
determination method or standard
IDA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
retrieved
8 April 2019
stated in
Expression of serotonin receptors 2B and 4 in human prostate cancer tissue and effects of their antagonists on prostate cancer cell lines
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IDA
integral component of membrane
determination method or standard
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
membrane
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
plasma membrane
determination method or standard
IDA
TAS
IEA
9 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
retrieved
8 April 2019
stated in
The human serotonin 5-HT2B receptor: pharmacological link between 5-HT2 and 5-HT1D receptors
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IDA
retrieved
8 April 2019
stated in
The natural mutation encoding a C terminus-truncated 5-hydroxytryptamine 2B receptor is a gain of proliferative functions
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IDA
retrieved
8 April 2019
stated in
Agonist-directed trafficking of signalling at serotonin 5-HT2A, 5-HT2B and 5-HT2C-VSV receptors mediated Gq/11 activation and calcium mobilisation in CHO cells
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IDA
retrieved
8 April 2019
stated in
Molecular and pharmacological characterization of serotonin 5-HT2A and 5-HT2B receptor subtypes in dog
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IDA
retrieved
8 April 2019
stated in
Agonist actions of dihydroergotamine at 5-HT2B and 5-HT2C receptors and their possible relevance to antimigraine efficacy
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IDA
retrieved
8 April 2019
stated in
Serotonin and angiotensin receptors in cardiac fibroblasts coregulate adrenergic-dependent cardiac hypertrophy
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IDA
synapse
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
cell junction
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
neuron projection
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
integral component of plasma membrane
determination method or standard
IEA
1 reference
retrieved
21 June 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P41595&geneProductId=UniProtKB:P41595
determination method or standard
IEA
nucleoplasm
determination method or standard
IDA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IDA
integral component of plasma membrane
determination method or standard
IBA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IBA
dendrite
determination method or standard
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IBA
biological process
intestine smooth muscle contraction
determination method or standard
IMP
2 references
retrieved
8 April 2019
stated in
Functional evidence for a 5‐HT2B receptor mediating contraction of longitudinal muscle in human small intestine
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IMP
retrieved
8 April 2019
stated in
5-HT1D and 5-HT2B receptors mediate contraction of smooth muscle in human small intestine
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IMP
smooth muscle contraction
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
G protein-coupled receptor internalization
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
release of sequestered calcium ion into cytosol
determination method or standard
IDA
IMP
4 references
retrieved
8 April 2019
stated in
5-HT2B receptor-mediated calcium release from ryanodine-sensitive intracellular stores in human pulmonary artery endothelial cells
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IMP
retrieved
8 April 2019
stated in
Agonist-directed trafficking of signalling at serotonin 5-HT2A, 5-HT2B and 5-HT2C-VSV receptors mediated Gq/11 activation and calcium mobilisation in CHO cells
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IMP
retrieved
8 April 2019
stated in
Characterization of the 5-HT2b receptor in evaluation of aequorin detection of calcium mobilization for miniaturized GPCR high-throughput screening
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IMP
retrieved
8 April 2019
stated in
Molecular and pharmacological characterization of serotonin 5-HT2A and 5-HT2B receptor subtypes in dog
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IDA
regulation of behavior
determination method or standard
IEA
IMP
3 references
retrieved
8 April 2019
stated in
A population-specific HTR2B stop codon predisposes to severe impulsivity
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IMP
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
positive regulation of endothelial cell proliferation
determination method or standard
IEA
IMP
2 references
retrieved
8 April 2019
stated in
Depletion of serotonin and selective inhibition of 2B receptor suppressed tumor angiogenesis by inhibiting endothelial nitric oxide synthase and extracellular signal-regulated kinase 1/2 phosphorylation
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IMP
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
positive regulation of MAP kinase activity
determination method or standard
IDA
1 reference
retrieved
8 April 2019
stated in
The natural mutation encoding a C terminus-truncated 5-hydroxytryptamine 2B receptor is a gain of proliferative functions
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IDA
phosphorylation
determination method or standard
IMP
1 reference
retrieved
8 April 2019
stated in
Depletion of serotonin and selective inhibition of 2B receptor suppressed tumor angiogenesis by inhibiting endothelial nitric oxide synthase and extracellular signal-regulated kinase 1/2 phosphorylation
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IMP
positive regulation of cytokine production
determination method or standard
IDA
1 reference
retrieved
8 April 2019
stated in
Serotonin and angiotensin receptors in cardiac fibroblasts coregulate adrenergic-dependent cardiac hypertrophy
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IDA
vasoconstriction
determination method or standard
IEA
IMP
2 references
retrieved
8 April 2019
stated in
The natural mutation encoding a C terminus-truncated 5-hydroxytryptamine 2B receptor is a gain of proliferative functions
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IMP
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
ERK1 and ERK2 cascade
determination method or standard
IEA
IMP
2 references
retrieved
8 April 2019
stated in
Depletion of serotonin and selective inhibition of 2B receptor suppressed tumor angiogenesis by inhibiting endothelial nitric oxide synthase and extracellular signal-regulated kinase 1/2 phosphorylation
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IMP
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
positive regulation of phosphatidylinositol biosynthetic process
determination method or standard
IDA
1 reference
retrieved
8 April 2019
stated in
Pharmacological characterization of mitogen-activated protein kinase activation by recombinant human 5-HT2C, 5-HT2A, and 5-HT2B receptors
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IDA
cardiac muscle hypertrophy
determination method or standard
ISS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
ISS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
heart morphogenesis
determination method or standard
ISS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
ISS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
cellular calcium ion homeostasis
determination method or standard
IDA
2 references
retrieved
8 April 2019
stated in
Pharmacological evidence for a functional serotonin-2B receptor in a human uterine smooth muscle cell line
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IDA
retrieved
8 April 2019
stated in
Pharmacological characterization of mitogen-activated protein kinase activation by recombinant human 5-HT2C, 5-HT2A, and 5-HT2B receptors
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IDA
neural crest cell differentiation
determination method or standard
ISS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
ISS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
negative regulation of apoptotic process
determination method or standard
ISS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
ISS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
negative regulation of cell death
determination method or standard
IMP
1 reference
retrieved
8 April 2019
stated in
Serotonin promotes tumor growth in human hepatocellular cancer
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IMP
activation of phospholipase C activity
determination method or standard
IDA
2 references
retrieved
8 April 2019
stated in
Pharmacological evidence for a functional serotonin-2B receptor in a human uterine smooth muscle cell line
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IDA
retrieved
8 April 2019
stated in
Pharmacological characterization of mitogen-activated protein kinase activation by recombinant human 5-HT2C, 5-HT2A, and 5-HT2B receptors
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IDA
protein kinase C signaling
determination method or standard
IMP
1 reference
retrieved
8 April 2019
stated in
Serotonin promotes tumor growth in human hepatocellular cancer
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IMP
cGMP biosynthetic process
determination method or standard
IDA
1 reference
retrieved
1 January 2018
stated in
Agonist actions of dihydroergotamine at 5-HT2B and 5-HT2C receptors and their possible relevance to antimigraine efficacy
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P41595&geneProductId=UniProtKB:P41595
determination method or standard
IDA
cellular response to temperature stimulus
determination method or standard
ISS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
ISS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
positive regulation of GTPase activity
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
development of the heart
determination method or standard
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
positive regulation of nitric-oxide synthase activity
determination method or standard
IDA
1 reference
retrieved
8 April 2019
stated in
The natural mutation encoding a C terminus-truncated 5-hydroxytryptamine 2B receptor is a gain of proliferative functions
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IDA
protein kinase C-activating G protein-coupled receptor signaling pathway
determination method or standard
ISS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
ISS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
embryonic morphogenesis
determination method or standard
ISS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
ISS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
serotonin receptor signaling pathway
determination method or standard
IMP
1 reference
retrieved
8 April 2019
stated in
Agonist-directed trafficking of signalling at serotonin 5-HT2A, 5-HT2B and 5-HT2C-VSV receptors mediated Gq/11 activation and calcium mobilisation in CHO cells
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IMP
neural crest cell migration
determination method or standard
ISS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
ISS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
positive regulation of cell population proliferation
determination method or standard
IDA
IMP
2 references
retrieved
8 April 2019
stated in
Expression of serotonin receptors 2B and 4 in human prostate cancer tissue and effects of their antagonists on prostate cancer cell lines
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IMP
retrieved
8 April 2019
stated in
The natural mutation encoding a C terminus-truncated 5-hydroxytryptamine 2B receptor is a gain of proliferative functions
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IDA
positive regulation of ERK1 and ERK2 cascade
determination method or standard
IDA
1 reference
retrieved
8 April 2019
stated in
Pharmacological characterization of mitogen-activated protein kinase activation by recombinant human 5-HT2C, 5-HT2A, and 5-HT2B receptors
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IDA
positive regulation of I-kappaB kinase/NF-kappaB signaling
determination method or standard
IEP
1 reference
retrieved
8 April 2019
stated in
Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEP
phosphatidylinositol 3-kinase signaling
determination method or standard
IDA
1 reference
retrieved
8 April 2019
stated in
Pharmacological evidence for a functional serotonin-2B receptor in a human uterine smooth muscle cell line
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IDA
negative regulation of autophagy
determination method or standard
IMP
1 reference
retrieved
8 April 2019
stated in
Serotonin promotes tumor growth in human hepatocellular cancer
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IMP
positive regulation of cell division
determination method or standard
ISS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
ISS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
calcium-mediated signaling
determination method or standard
IMP
1 reference
retrieved
8 April 2019
stated in
5-HT2B receptor-mediated calcium release from ryanodine-sensitive intracellular stores in human pulmonary artery endothelial cells
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IMP
signal transduction
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
phospholipase C-activating G protein-coupled receptor signaling pathway
determination method or standard
IBA
1 reference
retrieved
21 June 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P41595&geneProductId=UniProtKB:P41595
determination method or standard
IBA
G protein-coupled serotonin receptor signaling pathway
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
G protein-coupled receptor signaling pathway
determination method or standard
IEA
IMP
TAS
4 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
TAS
retrieved
8 April 2019
stated in
The natural mutation encoding a C terminus-truncated 5-hydroxytryptamine 2B receptor is a gain of proliferative functions
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IMP
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
animal behavior
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IEA
cGMP-mediated signaling
determination method or standard
IDA
1 reference
retrieved
8 April 2019
stated in
Agonist actions of dihydroergotamine at 5-HT2B and 5-HT2C receptors and their possible relevance to antimigraine efficacy
GOA
curator
UniProt
UniProt protein ID
P41595
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IDA
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
determination method or standard
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IBA
chemical synaptic transmission
determination method or standard
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41595
determination method or standard
IBA
physically interacts with
lysergic acid diethylamide
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
17
language of work or name
English
retrieved
17 August 2016
5-carboxamidotryptamine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
4
language of work or name
English
retrieved
17 August 2016
serotonin
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
5
language of work or name
English
retrieved
17 August 2016
(+/-)-8-hydroxy-2-(di-N-propylamino)tetralin
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
7
language of work or name
English
retrieved
17 August 2016
AL-37350A
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
160
language of work or name
English
retrieved
17 August 2016
α-methyl-5-HT
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
152
language of work or name
English
retrieved
17 August 2016
(RS)-brolamfetamine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
163
language of work or name
English
retrieved
17 August 2016
BW723C86
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
161
language of work or name
English
retrieved
17 August 2016
cabergoline
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
37
language of work or name
English
retrieved
17 August 2016
CGS-12066A
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
109
language of work or name
English
retrieved
17 August 2016
4-iodo-2,5-dimethoxyphenylisopropylamine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
147
language of work or name
English
retrieved
17 August 2016
lorcaserin
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
2941
language of work or name
English
retrieved
17 August 2016
MK-212
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
165
language of work or name
English
retrieved
17 August 2016
norfenfluramine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
215
language of work or name
English
retrieved
17 August 2016
Org 12962
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
170
language of work or name
English
retrieved
17 August 2016
ORG-37684
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
171
language of work or name
English
retrieved
17 August 2016
pergolide
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
48
language of work or name
English
retrieved
17 August 2016
pindolol
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
91
language of work or name
English
retrieved
17 August 2016
quinpirole
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
2
language of work or name
English
retrieved
17 August 2016
quipazine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
173
language of work or name
English
retrieved
17 August 2016
ru-24969
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
23
language of work or name
English
retrieved
17 August 2016
1-(3-trifluoromethylphenyl)piperazine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
115
language of work or name
English
retrieved
17 August 2016
tryptamine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
125
language of work or name
English
retrieved
17 August 2016
VER-3323
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
168
language of work or name
English
retrieved
17 August 2016
brl-15572
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
10
language of work or name
English
retrieved
17 August 2016
ergotamine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
149
language of work or name
English
retrieved
17 August 2016
gr-127935
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
14
language of work or name
English
retrieved
17 August 2016
m-chlorophenylpiperazine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
142
language of work or name
English
retrieved
17 August 2016
methylergonovine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
150
language of work or name
English
retrieved
17 August 2016
methysergide
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
134
language of work or name
English
retrieved
17 August 2016
sb-216641
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
28
language of work or name
English
retrieved
17 August 2016
1-naphthylpiperazine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
3
language of work or name
English
retrieved
17 August 2016
agomelatine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
198
language of work or name
English
retrieved
17 August 2016
apomorphine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
33
language of work or name
English
retrieved
17 August 2016
bromocriptine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
35
language of work or name
English
retrieved
17 August 2016
clozapine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
38
language of work or name
English
retrieved
17 August 2016
fluoxetine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
203
language of work or name
English
retrieved
17 August 2016
glemanserin
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
186
language of work or name
English
retrieved
17 August 2016
haloperidol
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
86
language of work or name
English
retrieved
17 August 2016
ketanserin
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
88
language of work or name
English
retrieved
17 August 2016
L-741,626
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
177
language of work or name
English
retrieved
17 August 2016
lisuride
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
43
language of work or name
English
retrieved
17 August 2016
melatonin
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
224
language of work or name
English
retrieved
17 August 2016
mesulergine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
206
language of work or name
English
retrieved
17 August 2016
metergoline
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
133
language of work or name
English
retrieved
17 August 2016
metitepine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
89
language of work or name
English
retrieved
17 August 2016
(RS)-mianserin
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
135
language of work or name
English
retrieved
17 August 2016
seproxetine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
208
language of work or name
English
retrieved
17 August 2016
piboserod
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
225
language of work or name
English
retrieved
17 August 2016
piribedil
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
49
language of work or name
English
retrieved
17 August 2016
α-yohimbine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
136
language of work or name
English
retrieved
17 August 2016
ritanserin
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
97
language of work or name
English
retrieved
17 August 2016
roxindole
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
52
language of work or name
English
retrieved
17 August 2016
RS-102221
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
187
language of work or name
English
retrieved
17 August 2016
RS-127445
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
188
language of work or name
English
retrieved
17 August 2016
sarpogrelate
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
210
language of work or name
English
retrieved
17 August 2016
SB 204741
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
221
language of work or name
English
retrieved
17 August 2016
sb-206553
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
189
language of work or name
English
retrieved
17 August 2016
SB 242084
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
193
language of work or name
English
retrieved
17 August 2016
SB 243213
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
194
language of work or name
English
retrieved
17 August 2016
SB-277,011-A
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
143
language of work or name
English
retrieved
17 August 2016
SDZ SER-082
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
195
language of work or name
English
retrieved
17 August 2016
spiperone
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
99
language of work or name
English
retrieved
17 August 2016
spiramide
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
175
language of work or name
English
retrieved
17 August 2016
spiroxatrine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
53
language of work or name
English
retrieved
17 August 2016
terguride
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
56
language of work or name
English
retrieved
17 August 2016
trazodone
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
213
language of work or name
English
retrieved
17 August 2016
volinanserin
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
185
language of work or name
English
retrieved
17 August 2016
xanomeline
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
57
language of work or name
English
retrieved
17 August 2016
yohimbine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
102
language of work or name
English
retrieved
17 August 2016
zimeldine
object of statement has role
antagonist
1 reference
stated in
Open Targets Platform
retrieved
14 August 2023
reference URL
https://platform.opentargets.org/drug/CHEMBL37744
Gene Atlas image
PBB GE HTR2B 206638 at fs.png
732 × 530; 11 KB
0 references
has part(s)
GPCR, rhodopsin-like, 7TM
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P41595
Identifiers
RefSeq protein ID
NP_000858
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
3357
NP_001307687
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
3357
XP_005246577
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
3357
XP_006712545
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
3357
UniProt protein ID
P41595
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P41595
Ensembl protein ID
ENSP00000258400
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000258400
Freebase ID
/m/03d36df
1 reference
stated in
Freebase Data Dumps
publication date
28 October 2013
Microsoft Academic ID
2781061528
0 references
2908955445
0 references
PDB structure ID
4NC3
1 reference
stated in
UniProt
UniProt protein ID
P41595
retrieved
9 August 2016
language of work or name
English
4IB4
1 reference
stated in
UniProt
UniProt protein ID
P41595
retrieved
9 August 2016
language of work or name
English
Transporter Classification Database ID
9.A.14.3.7
2 references
stated in
Transporter Classification database
retrieved
13 March 2020
stated in
Transporter Classification database
retrieved
29 April 2020
Sitelinks
Wikipedia
(11 entries)
edit
cywiki
HTR2B
dewiki
5-HT2B-Rezeptor
enwiki
5-HT2B receptor
eswiki
Receptor 5-HT2B
fawiki
گیرنده ۲ بی سروتونین
plwiki
Receptor 5-HT2B
ruwiki
5-HT2B-рецептор
shwiki
5-HT2B receptor
srwiki
5-HT2B receptor
ukwiki
HTR2B
zhwiki
5-HT2B受體
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
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Multilingual sites
(0 entries)
edit
Retrieved from "
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5-hydroxytryptamine receptor 2B
(Q4639596)
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