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hypericin(Q425409)

From Wikidata

chemical compound

1:6:8:10:11:13-hexahydroxy-3:4-dimethyl-meso-naphthodianthrene-7:14-dione
hypericum red

Language	Label	Description	Also known as
default for all languages	No label defined
English	hypericin	chemical compound	1:6:8:10:11:13-hexahydroxy-3:4-dimethyl-meso-naphthodianthrene-7:14-dione hypericum red

Statements

type of chemical entity

0 references

aromatic polyketide

0 references

bisanthrone polyketide

0 references

chemical structure

Hypericin.svg
1,195 × 1,179; 28 KB

1 reference

imported from Wikimedia project

German Wikipedia

0 references

chemical formula

C₃₀H₁₆O₈

1 reference

language of work or name

hypericin(English)

19 November 2016

canonical SMILES

CC1=CC(=C2C3=C1C4=C5C(=C(C=C4C)O)C(=O)C6=C(C=C(C7=C6C5=C3C8=C7C(=CC(=C8C2=O)O)O)O)O)O

1 reference

language of work or name

hypericin(English)

19 November 2016

Cortinarius austrovenetus

1 reference

Pigments of Fungi, Part 8. Bianthraquinones from Dermocybe austroveneta

Hypericum perforatum

78 references

Characterisation of extracts of Hypericum perforatum L. using an on-line HPLC system with UV/visible and fluorescence detection prior to and after photochemical conversion of the effluent

Catalytic inhibition of human DNA topoisomerase IIalpha by hypericin, a naphthodianthrone from St. John's wort (Hypericum perforatum).

Analysis and stability of Hyperici oleum

Antidepressant Activity of Hypericum Perforatum and Hyperforin: the Neglected Possibility

Biochemical activities of extracts from Hypericum perforatum L. 5th communication: dopamine-beta-hydroxylase-product quantification by HPLC and inhibition by hypericins and flavonoids

Comparative chemical composition and variability of biological activity of methanolic extracts from Hypericum perforatum L.

Comparative evaluation of St. John's wort from different Italian regions

Comparison of German St. John's wort products according to hyperforin and total hypericin content.

Determination of hypericin and pseudohypericin in pharmaceutical preparations by liquid chromatography with fluorescence detection

Determination of Major Constituents in St. John's Wort Under Different Extraction Conditions

Determination of naphthodianthrones in plant extracts from Hypericum perforatum L. by liquid chromatography–electrospray mass spectrometry

Determination of St. John's Wort Components in Dietary Supplements and Functional Foods by Liquid Chromatography

Determining hyperforin and hypericin content in eight brands of St. John's wort.

Development of a simple, rapid and reproducible HPLC assay for the simultaneous determination of hypericins and stabilized hyperforin in commercial St. John's wort preparations

Differential effects of light and nitrogen on production of hypericins and leaf glands in Hypericum perforatum

Effect of acute drought stress and time of harvest on phytochemistry and dry weight of St. John's wort leaves and flowers

Effect of light on hypericins contents in fresh flowering top parts and in an extract of St. John's Wort (Hypericum perforatum).

Effects of a Methanolic Extract and a Hyperforin-Enriched CO2Extract of St. John's Wort (Hypericum perforatum) on Intracerebral Field Potentials in the Freely Moving Rat (Tele-Stereo-EEG)

Effects of Visible and Ultraviolet Light on the Production of Hypericins and Flavonoids in Cell Cultures ofHypericum perforatum

Evaluation of chemical stability of St. John's wort commercial extract and some preparations

Extracts of St. John's wort and various constituents affect beta-adrenergic binding in rat frontal cortex

Factors affecting growth of cell suspension cultures of hypericum perforatum L. (St. John's wort) and production of hypericin

Fast high-performance liquid chromatographic analysis of naphthodianthrones and phloroglucinols from Hypericum perforatum extracts

High performance liquid chromatographic analysis of St. John's wort with photodiode array detection.

High-performance liquid chromatographic determination of the biologically active principle hypericin in phytotherapeutic vegetable extracts and alcoholic beverages

High-Performance Liquid Chromatography On-Line Coupled to High-Field NMR and Mass Spectrometry for Structure Elucidation of Constituents ofHypericum perforatumL.

HPLC-DAD and TLC-Densitometry for quantification of hypericin inHypericum perforatum L. Extracts

Hyperforin, Possibly the Major Non-Nitrogenous Secondary Metabolite of Hypericum perforatum L

Hypericin and Pseudohypericin in Cell Cultures of VariousHypericumSpecies and Chemotypes

Hypericin and pseudohypericin in some Hypericum species

Hypericin content of Nova Scotia biotypes of Hypericum perforatum L.

Hypericin content variation in Hypericum perforatum in Australia

Hypericum perforatum--chemical profiling and quantitative results of St. John's Wort products by an improved high-performance liquid chromatography method

Hypericum perforatum L. - chemotype without rutin from Italy

Hypericum perforatum subspecies angustifolium shows a protective activity on the consequences of unavoidable stress exposure at lower doses than Hypericum perforatum perforatum.

Identification by high-performance liquid chromatography–diode array detection–mass spectrometry and quantification by high-performance liquid chromatography–UV absorbance detection of active constituents of Hypericum perforatum

Improved procedure for the quality control of Hypericum perforatum L.

Induction of hypericins in Hypericum perforatum in response to chromium

Influence of nitrogen on the production of hypericins by St. John’s wort

Initiation of Shoot Organ Cultures ofHypericum perforatumand Formation of Hypericin Derivatives

In vitro and in vivo activation of hypericin with the incoherent light source PDT 1200 SOA (520-750 nm) and with solar simulated radiation (290-2500 nm).

Jasmonic acid-induced hypericin production in cell suspension cultures of Hypericum perforatum L. (St. John's wort).

On the nature of ?soluble? hypericin inHypericum species

Ontogenetic Variation Regarding Hypericin and Hyperforin Levels in Four Accessions ofHypericum perforatumL.

Pharmaceutical quality of hypericum extracts

Pharmacokinetics of Hypericin and Pseudohypericin after Oral Intake of the Hypericum Perforatum Extract LI 160 in Healthy Volunteers

Phenolic compounds from Hypericum perforatum

Pressurized liquid extraction of medicinal plants

Production of hypericin, pseudohypericin and flavonoids in cell cultures of various Hypericum species and their chemotypes

Pseudohypericin and hypericin in St. John's wort extracts. Breakdown of pseudohypericin

Quantitative analysis of the active components and the by-products of eight dry extracts of Hypericum perforatum L. (St John's Wort).

Quantitative changes of dianthrones, hyperforin and flavonoids content in the flower ontogenesis of Hypericum perforatum

Quantitative determination of biologically active constituents in medicinal plant crude extracts by thin-layer chromatography—densitometry

Quantitative evaluation of some species of St. John's wort for their level of hypericins by the HPLC method

Quantitative phytochemical analyses of six hypericum species growing in slovenia

RAPID ISOCRATIC HPLC ANALYSIS OF HYPERICINS

Regional differences in hypericin and pseudohypericin concentrations and five morphological traits among Hypericum perforatum plants in the northwestern United States

Sedative activity in mice of a hydroalcohol extract ofHypericum perforatum L.

Separation of hypericins and hyperforins in extracts of Hypericum perforatum L. using non-aqueous capillary electrophoresis with reversed electro-osmotic flow

Significance of Genetic and Environmental Aspects in the Field Cultivation ofHypericum perforatum

Simultaneous Determination of the Predominant Hyperforins and Hypericins in St. John's Wort (Hypericum perforatum L.) by Liquid Chromatography

Solubilized Hypericin and Pseudohypericin fromHypericum perforatumExert Antidepressant Activity in the Forced Swimming Test3

Step by step removal of hyperforin and hypericin: activity profile of different Hypericum preparations in behavioral models

Stimulation of the production of hypericins by mannan in Hypericum perforatum shoot cultures

The analysis of the kinetics of extraction of resinoids and hypericines from the amber, Hypericum perforatum L

The content of hypericins and phloroglucinols in Hypericum perforatum L. seedlings at early stage of development

THE DEVELOPMENT AND EVALUATION OF AN HPLC-DAD METHOD FOR THE ANALYSIS OF THE PHENOLIC FRACTIONS FROM IN VIVO AND IN VITRO BIOMASS OF HYPERICUM SPECIES

The spectral properties of Hypericum perforatum leaves: the implications for its photoactivated defences

Variation in Hypericins from Wild Populations of Hypericum perforatum L. in the Pacific Northwest of the U.S.A1

Note Variations in Hypericin Concentrations in Hypericum perforatum L. and Commercial Products

Cytotoxic activity of Hypericum perforatum L. on K562 erythroleukemic cells: differential effects between methanolic extract and hypericin

Seasonal variation in hypericin content of Hypericum perforatum L. (St. John's Wort).

Phytochemical analysis and genetic characterization of six Hypericum species from Serbia

High performance liquid chromatography/electrospray mass spectrometry of Hypericum perforatum extracts

Evaluation of major active components in St. John's Wort dietary supplements by high-performance liquid chromatography with photodiode array detection and electrospray mass spectrometric confirmation

Pharmaceutical Quality of Hypericum Extracts

Optimization of extraction conditions for active components in Hypericum perforatum using response surface methodology

Investigations on the Infraspecific Variability of Hypericum perforatum L.

Hypericum maculatum

8 references

Phytochemical analysis and genetic characterization of six Hypericum species from Serbia

Flavonoids and silicon in certain plant pollen

Hypericin and Pseudohypericin in Cell Cultures of VariousHypericumSpecies and Chemotypes

Hypericin and pseudohypericin in some Hypericum species

Production of hypericin, pseudohypericin and flavonoids in cell cultures of various Hypericum species and their chemotypes

Quantitative evaluation of some species of St. John's wort for their level of hypericins by the HPLC method

Quantitative phytochemical analyses of six hypericum species growing in slovenia

Seasonal variation in hypericin content of Hypericum perforatum L. (St. John's Wort).

Hypericum tetrapterum

5 references

Phytochemical analysis and genetic characterization of six Hypericum species from Serbia

Hypericin and pseudohypericin in some Hypericum species

Quantitative evaluation of some species of St. John's wort for their level of hypericins by the HPLC method

Quantitative phytochemical analyses of six hypericum species growing in slovenia

Seasonal variation in hypericin content of Hypericum perforatum L. (St. John's Wort).

Thielavia subthermophila

1 reference

Light-independent metabolomics of endophytic Thielavia subthermophila provides insight into microbial hypericin biosynthesis

Fagopyrum esculentum

1 reference

The effect of purified extract of Fagopyrum esculentum (buckwheat) on protein kinases involved in signal transduction pathways.

Hypericum ascyron

1 reference

Quantitative evaluation of some species of St. John's wort for their level of hypericins by the HPLC method

Hypericum balearicum

1 reference

Production of hypericin, pseudohypericin and flavonoids in cell cultures of various Hypericum species and their chemotypes

Hypericum elodes

1 reference

Detection of hypericins in the "red glands" of Hypericum elodes by ESI-MS/MS.

Hypericum glandulosum

1 reference

Production of hypericin, pseudohypericin and flavonoids in cell cultures of various Hypericum species and their chemotypes

Hypericum grandifolium

1 reference

HPLC-MS analysis and anti-oedematogenic activity of Hypericum grandifolium Choisy (Hypericaceae).

Hypericum humifusum

3 references

Quantitative phytochemical analyses of six hypericum species growing in slovenia

Hypericin and pseudohypericin in some Hypericum species

Seasonal variation in hypericin content of Hypericum perforatum L. (St. John's Wort).

Hypericum montanum

3 references

Hypericin and pseudohypericin in some Hypericum species

Quantitative phytochemical analyses of six hypericum species growing in slovenia

Seasonal variation in hypericin content of Hypericum perforatum L. (St. John's Wort).

Hypericum scabrum

1 reference

Quantitative evaluation of some species of St. John's wort for their level of hypericins by the HPLC method

Hypericum tomentosum

1 reference

Production of hypericin, pseudohypericin and flavonoids in cell cultures of various Hypericum species and their chemotypes

Hypericum venustum

1 reference

Phenolic constituents and the in vitro antioxidant activity of the flowers of Hypericum venustum

Rumex tianschanicus

1 reference

Chemical composition of the hybrid Rumex K-1

Hypericum coris

2 references

Hypericin and pseudohypericin in some Hypericum species

Seasonal variation in hypericin content of Hypericum perforatum L. (St. John's Wort).

Hypericum pulchrum

2 references

Hypericin and pseudohypericin in some Hypericum species

Seasonal variation in hypericin content of Hypericum perforatum L. (St. John's Wort).

Hypericum erectum

1 reference

Phytochemical analysis and genetic characterization of six Hypericum species from Serbia

Hypericum sampsonii

1 reference

Phytochemical analysis and genetic characterization of six Hypericum species from Serbia

Hypericum faberi

1 reference

Phytochemical analysis and genetic characterization of six Hypericum species from Serbia

Hypericum wightianum

1 reference

Phytochemical analysis and genetic characterization of six Hypericum species from Serbia

Hypericum barbatum

2 references

Phytochemical analysis and genetic characterization of six Hypericum species from Serbia

Hypericin and pseudohypericin in some Hypericum species

Hypericum linarioides

2 references

Phytochemical analysis and genetic characterization of six Hypericum species from Serbia

Hypericin and pseudohypericin in some Hypericum species

Hypericum rumeliacum

2 references

Phytochemical analysis and genetic characterization of six Hypericum species from Serbia

Hypericin and pseudohypericin in some Hypericum species

Hypericum triquetrifolium

3 references

Antioxidant activity of methanolic extract of Hypericum triquetrifolium Turra aerial part

Determination of hypericin content in Hypericum triquetrifolium Turra (Hypericaceae) growing wild in Jordan

Hypericin and pseudohypericin in some Hypericum species

Hypericum hirsutum

4 references

Quantitative evaluation of some species of St. John's wort for their level of hypericins by the HPLC method

Quantitative phytochemical analyses of six hypericum species growing in slovenia

Hypericin and pseudohypericin in some Hypericum species

Isolation and activity of the photodynamic pigment hypericin

Hypericum bithynicum

2 references

Hypericin and pseudohypericin in some Hypericum species

Production of hypericin, pseudohypericin and flavonoids in cell cultures of various Hypericum species and their chemotypes

Hypericum elegans

2 references

Hypericin and pseudohypericin in some Hypericum species

Quantitative evaluation of some species of St. John's wort for their level of hypericins by the HPLC method

Hypericum olympicum

1 reference

Hypericin and pseudohypericin in some Hypericum species

Hypericum cerastoides

1 reference

Hypericin and pseudohypericin in some Hypericum species

Hypericum origanifolium

1 reference

Hypericin and pseudohypericin in some Hypericum species

Hypericum montbretii

1 reference

Hypericin and pseudohypericin in some Hypericum species

Hypericum richeri

1 reference

Hypericin and pseudohypericin in some Hypericum species

Hypericum thasium

1 reference

Hypericin and pseudohypericin in some Hypericum species

Hypericum annulatum

1 reference

Hypericin and pseudohypericin in some Hypericum species

Hypericum empetrifolium

1 reference

Hypericin and pseudohypericin in some Hypericum species

Hypericum umbellatum

1 reference

Hypericin and pseudohypericin in some Hypericum species

Hypericum rochelii

1 reference

Hypericin and pseudohypericin in some Hypericum species

Hypericum attenuatum

1 reference

Hypericin and pseudohypericin in some Hypericum species

Hypericum polyphyllum

1 reference

Hypericin and pseudohypericin in some Hypericum species

Hypericum cerastioides

1 reference

Hypericin and pseudohypericin in some Hypericum species

Hypericum perfoliatum

1 reference

Hypericin and pseudohypericin in some Hypericum species

Hypericum aucheri

1 reference

Hypericin and pseudohypericin in some Hypericum species

504.084517dalton

1 reference

language of work or name

hypericin(English)

5 October 2016

subject has role

1 reference

Medical Subject Headings

MeSH descriptor ID

15 March 2018

antiviral agent

1 reference

Medical Subject Headings

MeSH descriptor ID

15 March 2018

enzyme inhibitor

1 reference

Medical Subject Headings

MeSH descriptor ID

15 March 2018

1 reference

Medical Subject Headings

MeSH descriptor ID

15 March 2018

immunosuppressive drug

1 reference

Medical Subject Headings

MeSH descriptor ID

15 March 2018

radiosensitizer

1 reference

Medical Subject Headings

MeSH descriptor ID

15 March 2018

Commons category

Hypericin

0 references

Identifiers

InChI=1S/C30H16O8/c1-7-3-9(31)19-23-15(7)16-8(2)4-10(32)20-24(16)28-26-18(12(34)6-14(36)22(26)30(20)38)17-11(33)5-13(35)21(29(19)37)25(17)27(23)28/h3-6,31-36H,1-2H3

1 reference

language of work or name

hypericin(English)

19 November 2016

BTXNYTINYBABQR-UHFFFAOYSA-N

2 references

language of work or name

hypericin(English)

19 November 2016

ChEBI release 2020-09-01

CAS Registry Number

2 references

Global Substance Registration System

language of work or name

hypericin(English)

19 November 2016

BTXNYTINYBABQR-UHFFFAOYSA-N

CAS Common Chemistry

9 April 2021

https://commonchemistry.cas.org/detail?cas_rn=548-04-9

1 reference

language of work or name

Hypericin(English)

19 November 2016

reason for deprecated rank

deprecated identifier value

1 reference

language of work or name

hypericin(English)

19 November 2016

Reaxys registry number

1917913

1 reference

language of work or name

hypericin(English)

5 October 2016

926160

0 references

mapping relation type

2 references

language of work or name

HYPERICIN(English)

19 November 2016

matched by identifier from

International Chemical Identifier

InChI=1S/C30H16O8/c1-7-3-9(31)19-23-15(7)16-8(2)4-10(32)20-24(16)28-26-18(12(34)6-14(36)22(26)30(20)38)17-11(33)5-13(35)21(29(19)37)25(17)27(23)28/h3-6,31-36H,1-2H3

1 reference

language of work or name

HYPERICIN(English)

19 November 2016

2 references

based on heuristic

inferred from InChIKey

matched by identifier from

BTXNYTINYBABQR-UHFFFAOYSA-N

splash10-0a4i-0000590000-d6f4544a5f160b2a5b67

0 references

splash10-0aq3-0001900000-4120181a887058e912cc

0 references

NMRShiftDB structure ID

1 reference

matched by identifier from

BTXNYTINYBABQR-UHFFFAOYSA-N

DSSTox substance ID

2 references

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

matched by identifier from

BTXNYTINYBABQR-UHFFFAOYSA-N

DSSTOX compound identifier

0 references

1 reference

Global Substance Registration System

language of work or name

hypericin(English)

19 November 2016

ECHA Substance Infocard ID

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

27 December 2018

1,3,4,6,8,13-hexahydroxy-10,11-dimethylphenanthro[1,10,9,8-opqra]perylene-7,14-dione(English)

CAS no.: 548-04-9(English)

1 reference

imported from Wikimedia project

Japanese Wikipedia

MeSH descriptor ID

1 reference

Medical Subject Headings

MeSH descriptor ID

14 March 2018

1 reference

Global Substance Registration System

language of work or name

hypericin(English)

19 November 2016

1 reference

matched by identifier from

BTXNYTINYBABQR-UHFFFAOYSA-N

Human Metabolome Database ID

2 references

based on heuristic

inferred from InChIKey

matched by identifier from

BTXNYTINYBABQR-UHFFFAOYSA-N

3 references

language of work or name

hypericin(English)

5 October 2016

based on heuristic

inferred from InChIKey

matched by identifier from

BTXNYTINYBABQR-UHFFFAOYSA-N

2 references

Global Substance Registration System

language of work or name

hypericin(English)

19 November 2016

matched by identifier from

BTXNYTINYBABQR-UHFFFAOYSA-N

Probes And Drugs ID

0 references

1 reference

language of work or name

hypericin(English)

5 October 2016

0 references

1 reference

Freebase Data Dumps

publication date

28 October 2013

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

Wikipedia(21 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(1 entry)

commonswikiCategory:Hypericin

Retrieved from "https://www.wikidata.org/w/index.php?title=Q425409&oldid=2433235641"

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