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5-hydroxytryptamine receptor 1A
(Q21115043)
Item
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From Wikidata
mammalian protein found in Homo sapiens
Serotonin receptor 1A
5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
G-21
guanine nucleotide-binding regulatory protein-coupled receptor
5-HT1a receptor
HTR1A
edit
Language
Label
Description
Also known as
default for all languages
No label defined
–
English
5-hydroxytryptamine receptor 1A
mammalian protein found in Homo sapiens
Serotonin receptor 1A
5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
G-21
guanine nucleotide-binding regulatory protein-coupled receptor
5-HT1a receptor
HTR1A
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P08908
part of
5-hydroxytryptamine 1A receptor
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P08908
GPCR, rhodopsin-like, 7TM, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P08908
encoded by
HTR1A
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P08908
molecular function
G protein-coupled receptor activity
determination method or standard
IEA
2 references
retrieved
16 July 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P08908
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P08908&geneProductId=UniProtKB:P08908
determination method or standard
IEA
retrieved
16 July 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P08908&geneProductId=UniProtKB:P08908
determination method or standard
IEA
signal transducer activity
determination method or standard
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P08908
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P08908&geneProductId=UniProtKB:P08908
determination method or standard
IEA
G protein-coupled serotonin receptor activity
determination method or standard
IDA
IEA
IMP
TAS
5 references
retrieved
16 July 2018
stated in
Increase in Serotonin-1A Autoreceptors in the Midbrain of Suicide Victims with Major Depression—Postmortem Evidence for Decreased Serotonin Activity
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P08908&geneProductId=UniProtKB:P08908
determination method or standard
TAS
retrieved
16 July 2018
stated in
Role of glycosphingolipids in the function of human serotonin1A receptors
GOA
curator
UniProt
UniProt protein ID
P08908
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P08908&geneProductId=UniProtKB:P08908
determination method or standard
IMP
retrieved
16 July 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P08908&geneProductId=UniProtKB:P08908
determination method or standard
IEA
retrieved
16 July 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P08908&geneProductId=UniProtKB:P08908
determination method or standard
IEA
retrieved
16 July 2018
stated in
Expression of 5HT1a receptors on activated human T cells. Regulation of cyclic AMP levels and T cell proliferation by 5-hydroxytryptamine
GOA
curator
UniProt
UniProt protein ID
P08908
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P08908&geneProductId=UniProtKB:P08908
determination method or standard
IDA
protein binding
determination method or standard
IPI
2 references
retrieved
8 April 2019
stated in
Dynamic modulation of FGFR1-5-HT1A heteroreceptor complexes. Agonist treatment enhances participation of FGFR1 and 5-HT1A homodimers and recruitment of β-arrestin2
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IPI
retrieved
8 April 2019
stated in
Fibroblast growth factor receptor 1- 5-hydroxytryptamine 1A heteroreceptor complexes and their enhancement of hippocampal plasticity
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IPI
serotonin binding
determination method or standard
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IBA
neurotransmitter receptor activity
determination method or standard
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IBA
receptor-receptor interaction
determination method or standard
IDA
1 reference
retrieved
8 April 2019
stated in
Dynamic modulation of FGFR1-5-HT1A heteroreceptor complexes. Agonist treatment enhances participation of FGFR1 and 5-HT1A homodimers and recruitment of β-arrestin2
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IDA
G protein-coupled receptor activity
determination method or standard
IBA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P08908
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IBA
G protein-coupled serotonin receptor activity
determination method or standard
IBA
IDA
IEA
IMP
TAS
6 references
retrieved
8 April 2019
stated in
Increase in Serotonin-1A Autoreceptors in the Midbrain of Suicide Victims with Major Depression—Postmortem Evidence for Decreased Serotonin Activity
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
TAS
retrieved
8 April 2019
stated in
Role of glycosphingolipids in the function of human serotonin1A receptors
GOA
curator
UniProt
UniProt protein ID
P08908
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IMP
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IEA
retrieved
8 April 2019
stated in
Expression of 5HT1a receptors on activated human T cells. Regulation of cyclic AMP levels and T cell proliferation by 5-hydroxytryptamine
GOA
curator
UniProt
UniProt protein ID
P08908
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IBA
cell component
integral component of membrane
determination method or standard
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P08908
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IEA
membrane
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P08908
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IEA
plasma membrane
determination method or standard
TAS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P08908
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IEA
integral component of plasma membrane
determination method or standard
IDA
IEA
TAS
3 references
retrieved
16 July 2018
stated in
The genomic clone G-21 which resembles a beta-adrenergic receptor sequence encodes the 5-HT1A receptor
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P08908&geneProductId=UniProtKB:P08908
determination method or standard
TAS
retrieved
16 July 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P08908&geneProductId=UniProtKB:P08908
determination method or standard
IEA
retrieved
16 July 2018
stated in
Role of glycosphingolipids in the function of human serotonin1A receptors
GOA
curator
UniProt
UniProt protein ID
P08908
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P08908&geneProductId=UniProtKB:P08908
determination method or standard
IDA
integral component of plasma membrane
determination method or standard
IBA
IDA
IEA
TAS
4 references
retrieved
8 April 2019
stated in
The genomic clone G-21 which resembles a beta-adrenergic receptor sequence encodes the 5-HT1A receptor
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
TAS
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IEA
retrieved
8 April 2019
stated in
Role of glycosphingolipids in the function of human serotonin1A receptors
GOA
curator
UniProt
UniProt protein ID
P08908
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IBA
dendrite
determination method or standard
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IBA
biological process
G protein-coupled receptor signaling pathway
determination method or standard
IEA
IMP
TAS
5 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
TAS
retrieved
8 April 2019
stated in
Activation of 5-HT1A receptors expressed in NIH-3T3 cells induces focus formation and potentiates EGF effect on DNA synthesis
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
TAS
retrieved
8 April 2019
stated in
Role of glycosphingolipids in the function of human serotonin1A receptors
GOA
curator
UniProt
UniProt protein ID
P08908
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IMP
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P08908
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IEA
regulation of behavior
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IEA
vasoconstriction
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IEA
adenylate cyclase-inhibiting serotonin receptor signaling pathway
determination method or standard
IDA
1 reference
retrieved
16 July 2018
stated in
Expression of 5HT1a receptors on activated human T cells. Regulation of cyclic AMP levels and T cell proliferation by 5-hydroxytryptamine
GOA
curator
UniProt
UniProt protein ID
P08908
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P08908&geneProductId=UniProtKB:P08908
determination method or standard
IDA
serotonin metabolic process
determination method or standard
ISS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P08908
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
ISS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IEA
behavioral fear response
determination method or standard
ISS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P08908
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
ISS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IEA
regulation of dopamine metabolic process
determination method or standard
ISS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P08908
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
ISS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IEA
regulation of serotonin secretion
determination method or standard
ISS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P08908
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
ISS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IEA
exploration behavior
determination method or standard
ISS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P08908
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
ISS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IEA
serotonin receptor signaling pathway
determination method or standard
ISS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P08908
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
ISS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IEA
positive regulation of cell population proliferation
determination method or standard
TAS
1 reference
retrieved
8 April 2019
stated in
Activation of 5-HT1A receptors expressed in NIH-3T3 cells induces focus formation and potentiates EGF effect on DNA synthesis
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
TAS
regulation of hormone secretion
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IEA
cell population proliferation
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IEA
signal transduction
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P08908
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IEA
animal behavior
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P08908
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IEA
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
determination method or standard
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IBA
adenylate cyclase-inhibiting serotonin receptor signaling pathway
determination method or standard
IBA
IDA
2 references
retrieved
8 April 2019
stated in
Expression of 5HT1a receptors on activated human T cells. Regulation of cyclic AMP levels and T cell proliferation by 5-hydroxytryptamine
GOA
curator
UniProt
UniProt protein ID
P08908
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IBA
chemical synaptic transmission
determination method or standard
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08908
determination method or standard
IBA
physically interacts with
flibanserin
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
8182
language of work or name
English
retrieved
17 August 2016
frovatriptan
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
7191
language of work or name
English
retrieved
17 August 2016
LP-12
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
8434
language of work or name
English
retrieved
17 August 2016
LP-211
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
8436
language of work or name
English
retrieved
17 August 2016
LP-44
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
8435
language of work or name
English
retrieved
17 August 2016
1-naphthylpiperazine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
3
language of work or name
English
retrieved
17 August 2016
5-carboxamidotryptamine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
4
language of work or name
English
retrieved
17 August 2016
serotonin
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
5
language of work or name
English
retrieved
17 August 2016
(+/-)-8-hydroxy-2-(di-N-propylamino)tetralin
has use
agonist
2 references
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
7
language of work or name
English
retrieved
17 August 2016
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
31
language of work or name
English
retrieved
17 August 2016
aripiprazole
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
34
language of work or name
English
retrieved
17 August 2016
bmy-14802
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
8
language of work or name
English
retrieved
17 August 2016
cabergoline
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
37
language of work or name
English
retrieved
17 August 2016
clozapine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
38
language of work or name
English
retrieved
17 August 2016
CP 93129
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
11
language of work or name
English
retrieved
17 August 2016
donitriptan
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
39
language of work or name
English
retrieved
17 August 2016
eletriptan
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
40
language of work or name
English
retrieved
17 August 2016
EMDT
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
12
language of work or name
English
retrieved
17 August 2016
flesinoxan
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
1
language of work or name
English
retrieved
17 August 2016
lisuride
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
43
language of work or name
English
retrieved
17 August 2016
lysergic acid diethylamide
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
17
language of work or name
English
retrieved
17 August 2016
LY293284
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
19
language of work or name
English
retrieved
17 August 2016
LY334370
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
20
language of work or name
English
retrieved
17 August 2016
nafadotride
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
44
language of work or name
English
retrieved
17 August 2016
naratriptan
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
45
language of work or name
English
retrieved
17 August 2016
F-15599
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
3924
language of work or name
English
retrieved
17 August 2016
ocaperidone
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
46
language of work or name
English
retrieved
17 August 2016
olanzapine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
47
language of work or name
English
retrieved
17 August 2016
quetiapine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
50
language of work or name
English
retrieved
17 August 2016
quinpirole
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
2
language of work or name
English
retrieved
17 August 2016
rizatriptan
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
51
language of work or name
English
retrieved
17 August 2016
ru-24969
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
23
language of work or name
English
retrieved
17 August 2016
S-14506
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
24
language of work or name
English
retrieved
17 August 2016
S-14671
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
25
language of work or name
English
retrieved
17 August 2016
spiroxatrine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
53
language of work or name
English
retrieved
17 August 2016
sumatriptan
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
54
language of work or name
English
retrieved
17 August 2016
tandospirone
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
55
language of work or name
English
retrieved
17 August 2016
U92016A
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
30
language of work or name
English
retrieved
17 August 2016
xanomeline
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
57
language of work or name
English
retrieved
17 August 2016
zalospirone
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
58
language of work or name
English
retrieved
17 August 2016
zolmitriptan
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
60
language of work or name
English
retrieved
17 August 2016
apomorphine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
33
language of work or name
English
retrieved
17 August 2016
BMY-7378
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
9
language of work or name
English
retrieved
17 August 2016
brl-15572
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
10
language of work or name
English
retrieved
17 August 2016
bromocriptine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
35
language of work or name
English
retrieved
17 August 2016
buspirone
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
36
language of work or name
English
retrieved
17 August 2016
fluparoxan
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
41
language of work or name
English
retrieved
17 August 2016
gr-127935
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
14
language of work or name
English
retrieved
17 August 2016
ipsapirone
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
42
language of work or name
English
retrieved
17 August 2016
pergolide
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
48
language of work or name
English
retrieved
17 August 2016
piribedil
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
49
language of work or name
English
retrieved
17 August 2016
roxindole
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
52
language of work or name
English
retrieved
17 August 2016
S-15535
has use
agonist
2 references
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
26
language of work or name
English
retrieved
17 August 2016
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
32
language of work or name
English
retrieved
17 August 2016
sb-216641
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
28
language of work or name
English
retrieved
17 August 2016
terguride
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
56
language of work or name
English
retrieved
17 August 2016
vilazodone
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
7427
language of work or name
English
retrieved
17 August 2016
vortioxetine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
7351
language of work or name
English
retrieved
17 August 2016
ziprasidone
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
59
language of work or name
English
retrieved
17 August 2016
(+)-butaclamol
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
62
language of work or name
English
retrieved
17 August 2016
chlorpromazine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
83
language of work or name
English
retrieved
17 August 2016
cyamemazine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
84
language of work or name
English
retrieved
17 August 2016
fluspirilene
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
85
language of work or name
English
retrieved
17 August 2016
haloperidol
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
86
language of work or name
English
retrieved
17 August 2016
iloperidone
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
87
language of work or name
English
retrieved
17 August 2016
apiose
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
68
language of work or name
English
retrieved
17 August 2016
ketanserin
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
88
language of work or name
English
retrieved
17 August 2016
mesoridazine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
7227
language of work or name
English
retrieved
17 August 2016
metitepine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
89
language of work or name
English
retrieved
17 August 2016
NAN 190
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
73
language of work or name
English
retrieved
17 August 2016
pimozide
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
90
language of work or name
English
retrieved
17 August 2016
pindolol
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
91
language of work or name
English
retrieved
17 August 2016
pipamperone
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
92
language of work or name
English
retrieved
17 August 2016
pizotyline
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
93
language of work or name
English
retrieved
17 August 2016
raclopride
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
94
language of work or name
English
retrieved
17 August 2016
repinotan
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
95
language of work or name
English
retrieved
17 August 2016
risperidone
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
96
language of work or name
English
retrieved
17 August 2016
ritanserin
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
97
language of work or name
English
retrieved
17 August 2016
Robalzotan
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
72
language of work or name
English
retrieved
17 August 2016
sertindole
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
98
language of work or name
English
retrieved
17 August 2016
spiperone
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
99
language of work or name
English
retrieved
17 August 2016
thioridazine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
100
language of work or name
English
retrieved
17 August 2016
tiospirone
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
101
language of work or name
English
retrieved
17 August 2016
WAY-100135
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
79
language of work or name
English
retrieved
17 August 2016
WAY-100635
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
80
language of work or name
English
retrieved
17 August 2016
yohimbine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
102
language of work or name
English
retrieved
17 August 2016
zotepine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
103
language of work or name
English
retrieved
17 August 2016
xaliproden
object of statement has role
agonist
1 reference
stated in
Open Targets Platform
retrieved
14 August 2023
reference URL
https://platform.opentargets.org/drug/CHEMBL1512580
zimeldine
object of statement has role
antagonist
1 reference
stated in
Open Targets Platform
retrieved
14 August 2023
reference URL
https://platform.opentargets.org/drug/CHEMBL37744
aripiprazole lauroxil
object of statement has role
Partial agonist
1 reference
stated in
Open Targets Platform
retrieved
14 August 2023
reference URL
https://platform.opentargets.org/drug/CHEMBL2219425
gepirone
object of statement has role
agonist
1 reference
stated in
Open Targets Platform
retrieved
14 August 2023
reference URL
https://platform.opentargets.org/drug/CHEMBL284092
buspirone hydrochloride
object of statement has role
Partial agonist
1 reference
stated in
Open Targets Platform
retrieved
14 August 2023
reference URL
https://platform.opentargets.org/drug/CHEMBL1200399
has part(s)
GPCR, rhodopsin-like, 7TM
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P08908
Commons category
5-HT1A serotonin receptor
0 references
topic's main category
Category:5-HT1A serotonin receptor
0 references
Identifiers
RefSeq protein ID
NP_000515
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
3350
UniProt protein ID
P08908
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P08908
Ensembl protein ID
ENSP00000316244
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000316244
ENSP00000423433
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000423433
Freebase ID
/m/03cx8d7
0 references
Guide to Pharmacology Target ID
1
1 reference
Wikimedia import URL
https://www.wikidata.org/w/index.php?title=Wikidata:Property_proposal/Guide_to_Pharmacology_Target_ID&oldid=709819452
Microsoft Academic ID
2781093953
0 references
2910224462
0 references
OpenAlex ID
C2781093953
1 reference
stated in
OpenAlex
retrieved
26 January 2022
reference URL
https://docs.openalex.org/download-snapshot/snapshot-data-format
archive URL
https://web.archive.org/web/20220125070108/https://docs.openalex.org/download-snapshot/snapshot-data-format
archive date
25 January 2022
Transporter Classification Database ID
9.A.14.3.14
2 references
stated in
Transporter Classification database
retrieved
13 March 2020
stated in
Transporter Classification database
retrieved
29 April 2020
Sitelinks
Wikipedia
(14 entries)
edit
arwiki
مستقبل 5-HT1A
dewiki
5-HT1A-Rezeptor
enwiki
5-HT1A receptor
eswiki
Receptor 5-HT1A
frwiki
Récepteur 5-HT1A
huwiki
5-HT1A-receptor
plwiki
Receptor 5-HT1A
ptwiki
Receptor 5-HT1A
ruwiki
5-HT1A-рецептор
shwiki
5-HT1A receptor
srwiki
5-HT1A receptor
trwiki
5-HT1A reseptörü
ukwiki
HTR1A
zhwiki
5-HT1A受体
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
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Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
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Multilingual sites
(0 entries)
edit
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