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Adrenoceptor alpha 2C
(Q4734891)
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From Wikidata
mammalian protein found in Homo sapiens
adrenergic, alpha-2C-, receptor
ADRA2C
alpha-2 adrenergic receptor subtype C4
alpha2-AR-C4
alpha-2CAR
alpha-2C adrenoceptor
alpha-2C adrenergic receptor
alpha-2C adrenoreceptor
edit
Language
Label
Description
Also known as
default for all languages
No label defined
–
English
Adrenoceptor alpha 2C
mammalian protein found in Homo sapiens
adrenergic, alpha-2C-, receptor
ADRA2C
alpha-2 adrenergic receptor subtype C4
alpha2-AR-C4
alpha-2CAR
alpha-2C adrenoceptor
alpha-2C adrenergic receptor
alpha-2C adrenoreceptor
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P18825
part of
Alpha 2C adrenoceptor
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P18825
GPCR, rhodopsin-like, 7TM, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P18825
encoded by
ADRA2C
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P18825
molecular function
G protein-coupled receptor activity
determination method or standard
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P18825
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IEA
epinephrine binding
determination method or standard
IDA
1 reference
retrieved
8 April 2019
stated in
Delayed transactivation of the receptor for nerve growth factor is required for sustained signaling and differentiation by alpha2-adrenergic receptors in transfected PC12 cells
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IDA
protein homodimerization activity
determination method or standard
IDA
1 reference
retrieved
8 April 2019
stated in
Alpha2A- and alpha2C-adrenergic receptors form homo- and heterodimers: the heterodimeric state impairs agonist-promoted GRK phosphorylation and beta-arrestin recruitment
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IDA
signal transducer activity
determination method or standard
IEA
1 reference
retrieved
31 October 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P18825
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P18825&geneProductId=UniProtKB:P18825
determination method or standard
IEA
adrenergic receptor activity
determination method or standard
IEA
1 reference
retrieved
16 July 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P18825&geneProductId=UniProtKB:P18825
determination method or standard
IEA
protein binding
determination method or standard
IPI
1 reference
retrieved
8 April 2019
stated in
Interaction of the amyloid precursor like protein 1 with the alpha2A-adrenergic receptor increases agonist-mediated inhibition of adenylate cyclase
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IPI
alpha-2A adrenergic receptor binding
determination method or standard
IPI
1 reference
retrieved
8 April 2019
stated in
Alpha2A- and alpha2C-adrenergic receptors form homo- and heterodimers: the heterodimeric state impairs agonist-promoted GRK phosphorylation and beta-arrestin recruitment
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IPI
alpha2-adrenergic receptor activity
determination method or standard
IDA
IEA
TAS
3 references
retrieved
8 April 2019
stated in
Molecular cloning, sequencing and functional study of the promoter region of the human α2C4-adrenergic receptor gene
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
TAS
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IEA
retrieved
8 April 2019
stated in
Delayed transactivation of the receptor for nerve growth factor is required for sustained signaling and differentiation by alpha2-adrenergic receptors in transfected PC12 cells
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IDA
protein heterodimerization activity
determination method or standard
IPI
1 reference
retrieved
8 April 2019
stated in
Alpha2A- and alpha2C-adrenergic receptors form homo- and heterodimers: the heterodimeric state impairs agonist-promoted GRK phosphorylation and beta-arrestin recruitment
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IPI
adrenergic receptor activity
determination method or standard
IBA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IBA
cell component
cytoplasm
determination method or standard
IDA
1 reference
retrieved
8 April 2019
stated in
Alpha2A- and alpha2C-adrenergic receptors form homo- and heterodimers: the heterodimeric state impairs agonist-promoted GRK phosphorylation and beta-arrestin recruitment
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IDA
axon terminus
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IEA
integral component of membrane
determination method or standard
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P18825
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IEA
endosome
determination method or standard
TAS
1 reference
retrieved
8 April 2019
stated in
Role of arrestins in endocytosis and signaling of alpha2-adrenergic receptor subtypes
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
TAS
membrane
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P18825
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IEA
plasma membrane
determination method or standard
TAS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P18825
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IEA
integral component of plasma membrane
determination method or standard
IDA
TAS
2 references
retrieved
16 July 2018
stated in
Molecular cloning, sequencing and functional study of the promoter region of the human α2C4-adrenergic receptor gene
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P18825&geneProductId=UniProtKB:P18825
determination method or standard
TAS
retrieved
16 July 2018
stated in
Alpha2A- and alpha2C-adrenergic receptors form homo- and heterodimers: the heterodimeric state impairs agonist-promoted GRK phosphorylation and beta-arrestin recruitment
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P18825&geneProductId=UniProtKB:P18825
determination method or standard
IDA
axon
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IEA
glutamatergic synapse
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IEA
integral component of postsynaptic membrane
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IEA
integral component of postsynaptic density membrane
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IEA
integral component of plasma membrane
determination method or standard
IBA
IDA
TAS
3 references
retrieved
8 April 2019
stated in
Molecular cloning, sequencing and functional study of the promoter region of the human α2C4-adrenergic receptor gene
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
TAS
retrieved
8 April 2019
stated in
Alpha2A- and alpha2C-adrenergic receptors form homo- and heterodimers: the heterodimeric state impairs agonist-promoted GRK phosphorylation and beta-arrestin recruitment
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IBA
soma
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IEA
biological process
G protein-coupled receptor signaling pathway
determination method or standard
TAS
IEA
5 references
retrieved
5 June 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P18825&geneProductId=UniProtKB:P18825
determination method or standard
TAS
retrieved
5 June 2018
stated in
Molecular cloning, sequencing and functional study of the promoter region of the human α2C4-adrenergic receptor gene
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P18825&geneProductId=UniProtKB:P18825
determination method or standard
TAS
retrieved
5 June 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P18825
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P18825&geneProductId=UniProtKB:P18825
determination method or standard
IEA
retrieved
5 June 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P18825&geneProductId=UniProtKB:P18825
determination method or standard
IEA
retrieved
5 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P18825&geneProductId=UniProtKB:P18825
determination method or standard
IEA
activation of protein kinase B activity
determination method or standard
IDA
1 reference
retrieved
8 April 2019
stated in
Delayed transactivation of the receptor for nerve growth factor is required for sustained signaling and differentiation by alpha2-adrenergic receptors in transfected PC12 cells
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IDA
negative regulation of epinephrine secretion
determination method or standard
NAS
1 reference
retrieved
8 April 2019
stated in
Interaction of the amyloid precursor like protein 1 with the alpha2A-adrenergic receptor increases agonist-mediated inhibition of adenylate cyclase
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
NAS
regulation of sensory perception of pain
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IEA
regulation of smooth muscle contraction
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IEA
regulation of insulin secretion
determination method or standard
TAS
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
TAS
female pregnancy
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IEA
cell-cell signaling
determination method or standard
TAS
1 reference
retrieved
8 April 2019
stated in
Molecular cloning, sequencing and functional study of the promoter region of the human α2C4-adrenergic receptor gene
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
TAS
negative regulation of norepinephrine secretion
determination method or standard
NAS
TAS
2 references
retrieved
8 April 2019
stated in
Interaction of the ubiquitin carboxyl terminal esterase L1 with alpha(2)-adrenergic receptors inhibits agonist-mediated p44/42 MAP kinase activation
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
TAS
retrieved
8 April 2019
stated in
Interaction of the amyloid precursor like protein 1 with the alpha2A-adrenergic receptor increases agonist-mediated inhibition of adenylate cyclase
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
NAS
negative regulation of uterine smooth muscle contraction
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IEA
adenylate cyclase-activating adrenergic receptor signaling pathway
determination method or standard
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IBA
regulation of vasoconstriction
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IEA
positive regulation of neuron differentiation
determination method or standard
IDA
1 reference
retrieved
8 April 2019
stated in
Delayed transactivation of the receptor for nerve growth factor is required for sustained signaling and differentiation by alpha2-adrenergic receptors in transfected PC12 cells
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IDA
positive regulation of vasoconstriction
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IEA
signal transduction
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P18825
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IEA
platelet activation
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IEA
positive regulation of MAPK cascade
determination method or standard
IDA
1 reference
retrieved
8 April 2019
stated in
Delayed transactivation of the receptor for nerve growth factor is required for sustained signaling and differentiation by alpha2-adrenergic receptors in transfected PC12 cells
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IDA
adrenergic receptor signaling pathway
determination method or standard
IDA
1 reference
retrieved
8 April 2019
stated in
Delayed transactivation of the receptor for nerve growth factor is required for sustained signaling and differentiation by alpha2-adrenergic receptors in transfected PC12 cells
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IDA
G protein-coupled receptor signaling pathway
determination method or standard
IDA
IEA
TAS
5 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P18825
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IEA
retrieved
8 April 2019
stated in
Delayed transactivation of the receptor for nerve growth factor is required for sustained signaling and differentiation by alpha2-adrenergic receptors in transfected PC12 cells
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IDA
receptor transactivation
determination method or standard
IDA
1 reference
retrieved
8 April 2019
stated in
Delayed transactivation of the receptor for nerve growth factor is required for sustained signaling and differentiation by alpha2-adrenergic receptors in transfected PC12 cells
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IDA
adenylate cyclase-modulating G protein-coupled receptor signaling pathway
determination method or standard
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18825
determination method or standard
IBA
physically interacts with
apraclonidine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
7117
language of work or name
English
retrieved
17 August 2016
guanabenz
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
5443
language of work or name
English
retrieved
17 August 2016
dexmedetomidine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
521
language of work or name
English
retrieved
17 August 2016
norepinephrine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
505
language of work or name
English
retrieved
17 August 2016
brimonidine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
520
language of work or name
English
retrieved
17 August 2016
clonidine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
516
language of work or name
English
retrieved
17 August 2016
guanfacine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
522
language of work or name
English
retrieved
17 August 2016
oxymetazoline
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
124
language of work or name
English
retrieved
17 August 2016
pergolide
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
48
language of work or name
English
retrieved
17 August 2016
xylazine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
523
language of work or name
English
retrieved
17 August 2016
apomorphine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
33
language of work or name
English
retrieved
17 August 2016
brl-44408
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
525
language of work or name
English
retrieved
17 August 2016
bromocriptine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
35
language of work or name
English
retrieved
17 August 2016
cabergoline
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
37
language of work or name
English
retrieved
17 August 2016
chlorpromazine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
83
language of work or name
English
retrieved
17 August 2016
lisuride
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
43
language of work or name
English
retrieved
17 August 2016
lurasidone
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
7461
language of work or name
English
retrieved
17 August 2016
mirtazapine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
7241
language of work or name
English
retrieved
17 August 2016
phentolamine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
502
language of work or name
English
retrieved
17 August 2016
piribedil
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
49
language of work or name
English
retrieved
17 August 2016
prazosin
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
503
language of work or name
English
retrieved
17 August 2016
α-yohimbine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
136
language of work or name
English
retrieved
17 August 2016
roxindole
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
52
language of work or name
English
retrieved
17 August 2016
spiroxatrine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
53
language of work or name
English
retrieved
17 August 2016
terguride
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
56
language of work or name
English
retrieved
17 August 2016
tolazoline
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
7310
language of work or name
English
retrieved
17 August 2016
WB-4101
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
499
language of work or name
English
retrieved
17 August 2016
yohimbine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
102
language of work or name
English
retrieved
17 August 2016
levonordefrin
object of statement has role
agonist
1 reference
stated in
Open Targets Platform
retrieved
14 August 2023
reference URL
https://platform.opentargets.org/drug/CHEMBL677
epinephrine
object of statement has role
agonist
1 reference
stated in
Open Targets Platform
retrieved
14 August 2023
reference URL
https://platform.opentargets.org/drug/CHEMBL679
norepinephrine
object of statement has role
agonist
1 reference
stated in
Open Targets Platform
retrieved
14 August 2023
reference URL
https://platform.opentargets.org/drug/CHEMBL1437
(−)-ephedrine
object of statement has role
agonist
1 reference
stated in
Open Targets Platform
retrieved
14 August 2023
reference URL
https://platform.opentargets.org/drug/CHEMBL211456
apraclonidine hydrochloride
object of statement has role
agonist
1 reference
stated in
Open Targets Platform
retrieved
14 August 2023
reference URL
https://platform.opentargets.org/drug/CHEMBL1200379
dipivefrin hydrochloride
object of statement has role
agonist
1 reference
stated in
Open Targets Platform
retrieved
14 August 2023
reference URL
https://platform.opentargets.org/drug/CHEMBL1200833
oxymetazoline hydrochloride
object of statement has role
agonist
1 reference
stated in
Open Targets Platform
retrieved
14 August 2023
reference URL
https://platform.opentargets.org/drug/CHEMBL1200791
phenoxybenzamine hydrochloride
object of statement has role
antagonist
1 reference
stated in
Open Targets Platform
retrieved
14 August 2023
reference URL
https://platform.opentargets.org/drug/CHEMBL1200787
dexmedetomidine hydrochloride
object of statement has role
agonist
1 reference
stated in
Open Targets Platform
retrieved
14 August 2023
reference URL
https://platform.opentargets.org/drug/CHEMBL2106195
has part(s)
GPCR, rhodopsin-like, 7TM
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P18825
Identifiers
RefSeq protein ID
NP_000674
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
152
UniProt protein ID
P18825
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P18825
Ensembl protein ID
ENSP00000386069
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000386069
ENSP00000426268
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000426268
Sitelinks
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(0 entries)
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(0 entries)
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Multilingual sites
(0 entries)
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