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Cocaine abusers have an overexpression of alpha-synuclein in dopamine neurons.
(Q44396203)
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From Wikidata
scientific article published in April 2003
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English
Cocaine abusers have an overexpression of alpha-synuclein in dopamine neurons.
scientific article published in April 2003
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12684441
retrieved
2 December 2017
title
Cocaine abusers have an overexpression of alpha-synuclein in dopamine neurons
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
6742069
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742069&resulttype=core&format=json
retrieved
12 May 2020
main subject
dopamine
0 references
overexpression
1 reference
based on heuristic
inferred from title
Synuclein
1 reference
based on heuristic
inferred from title
author
Deborah Mash
series ordinal
1
object named as
Deborah C Mash
1 reference
stated in
Europe PubMed Central
PMC publication ID
6742069
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742069&resulttype=core&format=json
retrieved
12 May 2020
Abraham Lieberman
series ordinal
6
object named as
Abraham Lieberman
1 reference
stated in
Europe PubMed Central
PMC publication ID
6742069
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742069&resulttype=core&format=json
retrieved
12 May 2020
author name string
Qinjie Ouyang
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
6742069
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742069&resulttype=core&format=json
retrieved
12 May 2020
John Pablo
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
6742069
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742069&resulttype=core&format=json
retrieved
12 May 2020
Margaret Basile
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
6742069
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742069&resulttype=core&format=json
retrieved
12 May 2020
Sari Izenwasser
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
6742069
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742069&resulttype=core&format=json
retrieved
12 May 2020
Richard J Perrin
series ordinal
7
1 reference
stated in
Europe PubMed Central
PMC publication ID
6742069
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742069&resulttype=core&format=json
retrieved
12 May 2020
publication date
1 April 2003
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12684441
retrieved
2 December 2017
language of work or name
English
0 references
published in
Journal of Neuroscience
1 reference
stated in
Europe PubMed Central
PMC publication ID
6742069
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742069&resulttype=core&format=json
retrieved
12 May 2020
volume
23
1 reference
stated in
Europe PubMed Central
PMC publication ID
6742069
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742069&resulttype=core&format=json
retrieved
12 May 2020
issue
7
1 reference
stated in
Europe PubMed Central
PMC publication ID
6742069
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742069&resulttype=core&format=json
retrieved
12 May 2020
page(s)
2564-2571
1 reference
stated in
Europe PubMed Central
PMC publication ID
6742069
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742069&resulttype=core&format=json
retrieved
12 May 2020
cites work
Cytotoxic and genotoxic potential of dopamine
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Alpha-synuclein expression in substantia nigra and cortex in Parkinson's disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Choreoathetoid movements in cocaine dependence
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Synucleins in synaptic plasticity and neurodegenerative disorders
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Increased expression of rat synuclein in the substantia nigra pars compacta identified by mRNA differential display in a model of developmental target injury
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Q64797127
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Q64791476
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A measure of striatal function predicts motor stereotypy.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A Drosophila model of Parkinson's disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Overexpression of human alpha-synuclein causes dopamine neuron death in rat primary culture and immortalized mesencephalon-derived cells.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Q64767196
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Expression of mutant alpha-synuclein causes increased susceptibility to dopamine toxicity
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Regulation of the vesicular monoamine transporter-2: a novel mechanism for cocaine and other psychostimulants
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Direct binding and functional coupling of alpha-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Kinetic Stabilization of the α-Synuclein Protofibril by a Dopamine-α-Synuclein Adduct
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
α-synuclein and cytosolic dopamine: Stabilizing a bad situation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Where does parkinson disease pathology begin in the brain?
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Dopamine-dependent neurotoxicity of alpha-synuclein: a mechanism for selective neurodegeneration in Parkinson disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Dopamine transport function is elevated in cocaine users
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Radiolabeling of dopamine uptake sites in mouse striatum: comparison of binding sites for cocaine, mazindol, and GBR 12935
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Long-term frontal brain metabolic changes in cocaine abusers
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The rat brain synucleins; family of proteins transiently associated with neuronal membrane
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Emerging patterns of cocaine use and the epidemic of cocaine overdose deaths in Dade County, Florida.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cerebral atrophy in habitual cocaine abusers: a planimetric CT study
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cocaine receptors labeled by [3H]2 beta-carbomethoxy-3 beta-(4-fluorophenyl)tropane.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cocaine receptors on dopamine transporters are related to self-administration of cocaine
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Synuclein: a neuron-specific protein localized to the nucleus and presynaptic nerve terminal
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cocaine-induced psychosis and sudden death in recreational cocaine users
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Agonal status affects the metabolic activity of nerve endings isolated from postmortem human brain
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Characterization of a novel protein regulated during the critical period for song learning in the zebra finch.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Molecular alterations in the neostriatum of human cocaine addicts
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
High affinity cocaine recognition sites on the dopamine transporter are elevated in fatal cocaine overdose victims
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Differing neurotoxic potencies of methamphetamine, mazindol, and cocaine in mesencephalic cultures
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Methamphetamine neurotoxicity involves vacuolation of endocytic organelles and dopamine-dependent intracellular oxidative stress.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Dissimilar patterns of degeneration in brain following four different addictive stimulants.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cocaine use increases [3H]WIN 35428 binding sites in human striatum
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Molecular characterization of the dopamine transporter.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Euphorigenic doses of cocaine reduce [123I]beta-CIT SPECT measures of dopamine transporter availability in human cocaine addicts
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Role of oxidation in the neurotoxic effects of intrastriatal dopamine injections
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Cocaine-associated agitated delirium and the neuroleptic malignant syndrome
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Neuropathology of Parkinson's disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Striatal dopamine, dopamine transporter, and vesicular monoamine transporter in chronic cocaine users
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Psychomotor and electroencephalographic sequelae of cocaine dependence
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Clinical and MRI evaluation of psychostimulant neurotoxicity.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Fatal excited delirium following cocaine use: epidemiologic findings provide new evidence for mechanisms of cocaine toxicity
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Binding of Abeta to alpha- and beta-synucleins: identification of segments in alpha-synuclein/NAC precursor that bind Abeta and NAC
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
α-Synuclein in Lewy bodies
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
AlaSOPro mutation in the gene encoding α-synuclein in Parkinson's disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Self‐oligomerization of NACP, the precursor protein of the non‐amyloid β/A4 protein (Aβ) component of Alzheimer's disease amyloid, observed in the presence of a C‐terminal Aβ fragment (residues 25–35)
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Regulation of Phospholipase D2: Selective Inhibition of Mammalian Phospholipase D Isoenzymes by α- and β-Synucleins
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson’s disease and dementia with Lewy bodies
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Elevated Striatal Dopamine Transporters During Acute Cocaine Abstinence as Measured by [123I]β-CIT SPECT
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Expression Pattern of Synucleins (Non‐Aβ Component of Alzheimer's Disease Amyloid Precursor Protein/α‐Synuclein) During Murine Brain Development
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Relapse to drug-seeking: neural and molecular mechanisms
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Brain dopamine transporter messenger RNA and binding sites in cocaine users: a postmortem study.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The Synuclein Family
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Novel alpha-synuclein-immunoreactive proteins in brain samples from the Contursi kindred, Parkinson's, and Alzheimer's disease.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/12684441
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1523/JNEUROSCI.23-07-02564.2003
1 reference
stated in
Europe PubMed Central
PMC publication ID
6742069
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742069&resulttype=core&format=json
retrieved
12 May 2020
PMC publication ID
6742069
1 reference
stated in
Europe PubMed Central
PMC publication ID
6742069
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742069&resulttype=core&format=json
retrieved
12 May 2020
PubMed publication ID
12684441
1 reference
stated in
Europe PubMed Central
PMC publication ID
6742069
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6742069&resulttype=core&format=json
retrieved
12 May 2020
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Cocaine abusers have an overexpression of alpha-synuclein in dopamine neurons.
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