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Hyperforin
(Q412742)
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From Wikidata
chemical compound
edit
Language
Label
Description
Also known as
default for all languages
No label defined
–
English
Hyperforin
chemical compound
Statements
instance of
type of chemical entity
0 references
subclass of
4-Hydroxy-8-methyl-3,5,7-tris(3-methylbut-2-enyl)-8-(4-methylpent-3-enyl)-1-(2-methylpropanoyl)bicyclo[3.3.1]non-3-ene-2,9-dione
1 reference
based on heuristic
inferred from InChIKey
chemical structure
Hyperforin-skeletal.png
963 × 1,033; 20 KB
0 references
stereoisomer of
(1S,5S,7S,8R)-4-hydroxy-8-methyl-3,5,7-tris(3-methylbut-2-enyl)-8-(4-methylpent-3-enyl)-1-(2-methylpropanoyl)bicyclo[3.3.1]non-3-ene-2,9-dione
2 references
based on heuristic
inferred from InChIKey
based on heuristic
inferred from InChI
ent-Hyperforin
1 reference
based on heuristic
inferred from InChI
chemical formula
C₃₅H₅₂O₄
2 references
imported from Wikimedia project
German Wikipedia
stated in
PubChem
canonical SMILES
CCCC(=O)C12C(=O)C(=C(C(C1=O)(CC(C2(C)CCC=C(C)C)CC=C(C)C)CC=C(C)C)O)CC=C(C)C
1 reference
stated in
PubChem
isomeric SMILES
CC(C)=CCC[C@]1(C)[C@@H](CC=C(C)C)C[C@@]2(CC=C(C)C)C(=O)[C@]1(C(=O)C(C)C)C(=O)C(CC=C(C)C)=C2O
0 references
found in taxon
Hypericum perforatum
55 references
stated in
Current St John's wort research from mode of action to clinical efficacy
stated in
Treatment with Hypericum perforatum L. does not trigger decreased resistance in Staphylococcus aureus against antibiotics and Hyperforin
stated in
High performance liquid chromatography/electrospray mass spectrometry of Hypericum perforatum extracts
stated in
Identification of the major constituents of Hypericum perforatum by LC/SPE/NMR and/or LC/MS.
stated in
Hypericum perforatum--chemical profiling and quantitative results of St. John's Wort products by an improved high-performance liquid chromatography method
stated in
Improved procedure for the quality control of Hypericum perforatum L.
stated in
Quantitative analysis of the active components and the by-products of eight dry extracts of Hypericum perforatum L. (St John's Wort).
stated in
Fast high-performance liquid chromatographic analysis of naphthodianthrones and phloroglucinols from Hypericum perforatum extracts
stated in
Comparative evaluation of St. John's wort from different Italian regions
stated in
Evaluation of major active components in St. John's Wort dietary supplements by high-performance liquid chromatography with photodiode array detection and electrospray mass spectrometric confirmation
stated in
Identification by high-performance liquid chromatography–diode array detection–mass spectrometry and quantification by high-performance liquid chromatography–UV absorbance detection of active constituents of Hypericum perforatum
stated in
Adhyperforin as a contributor to the effect of Hypericum perforatum L. in biochemical models of antidepressant activity
stated in
Step by step removal of hyperforin and hypericin: activity profile of different Hypericum preparations in behavioral models
stated in
The structure of hyperforin
stated in
The content of hypericins and phloroglucinols in Hypericum perforatum L. seedlings at early stage of development
stated in
Hypericum perforatum L. - chemotype without rutin from Italy
stated in
High performance liquid chromatographic analysis of St. John's wort with photodiode array detection.
stated in
Evaluation of chemical stability of St. John's wort commercial extract and some preparations
stated in
Development of a simple, rapid and reproducible HPLC assay for the simultaneous determination of hypericins and stabilized hyperforin in commercial St. John's wort preparations
stated in
Separation of hypericins and hyperforins in extracts of Hypericum perforatum L. using non-aqueous capillary electrophoresis with reversed electro-osmotic flow
stated in
Supercritical extraction of herbs I: Saw Palmetto, St John's Wort, Kava Root, and Echinacea
stated in
Clinical significance of hyperforin for the efficacy of Hypericum extracts on depressive disorders of different severities
stated in
Comparison of German St. John's wort products according to hyperforin and total hypericin content.
stated in
High-Performance Liquid Chromatography On-Line Coupled to High-Field NMR and Mass Spectrometry for Structure Elucidation of Constituents ofHypericum perforatumL.
stated in
Supercritical fluid extraction and high-performance liquid chromatographic determination of phloroglucinols in St. John's Wort (Hypericum perforatum L.).
stated in
Quantitative changes of dianthrones, hyperforin and flavonoids content in the flower ontogenesis of Hypericum perforatum
stated in
Phenolic compounds from Hypericum perforatum
stated in
Hypericum perforatum subspecies angustifolium shows a protective activity on the consequences of unavoidable stress exposure at lower doses than Hypericum perforatum perforatum.
stated in
Effect of acute drought stress and time of harvest on phytochemistry and dry weight of St. John's wort leaves and flowers
stated in
Significance of Genetic and Environmental Aspects in the Field Cultivation ofHypericum perforatum
stated in
Quantitative phytochemical analyses of six hypericum species growing in slovenia
stated in
Adhyperforin: A Homologue of Hyperforin from Hypericum perforatum
stated in
Analysis and stability of Hyperici oleum
stated in
Hyperforin, Possibly the Major Non-Nitrogenous Secondary Metabolite of Hypericum perforatum L
stated in
Antidepressant Activity of Hypericum Perforatum and Hyperforin: the Neglected Possibility
stated in
Activity Profiles of Two Hyperforin-Containing Hypericum Extracts in Behavioral Models
stated in
Effects of a Methanolic Extract and a Hyperforin-Enriched CO2Extract of St. John's Wort (Hypericum perforatum) on Intracerebral Field Potentials in the Freely Moving Rat (Tele-Stereo-EEG)
stated in
Oral Bioavailability of Hyperforin from Hypericum Extracts in Rats and Human Volunteers
stated in
Determination of Major Constituents in St. John's Wort Under Different Extraction Conditions
stated in
THE DEVELOPMENT AND EVALUATION OF AN HPLC-DAD METHOD FOR THE ANALYSIS OF THE PHENOLIC FRACTIONS FROM IN VIVO AND IN VITRO BIOMASS OF HYPERICUM SPECIES
stated in
Determining hyperforin and hypericin content in eight brands of St. John's wort.
stated in
A Simple and Reliable Semipreparative High-Performance Liquid Chromatography Technique for the Isolation of Marker-Grade Hyperforin from Hypericum perforatum L. Extract
stated in
Simultaneous Determination of the Predominant Hyperforins and Hypericins in St. John's Wort (Hypericum perforatum L.) by Liquid Chromatography
stated in
Determination of St. John's Wort Components in Dietary Supplements and Functional Foods by Liquid Chromatography
stated in
Pharmaceutical quality of hypericum extracts
stated in
Isolation, purity analysis and stability of hyperforin as a standard material from Hypericum perforatum L.
stated in
Ontogenetic Variation Regarding Hypericin and Hyperforin Levels in Four Accessions ofHypericum perforatumL.
stated in
Hyperforin a constituent of St John's wort (Hypericum perforatum L.) extract induces apoptosis by triggering activation of caspases and with hypericin synergistically exerts cytotoxicity towards human malignant cell lines
stated in
Inhibition of tumour cell growth by hyperforin, a novel anticancer drug from St. John's wort that acts by induction of apoptosis.
stated in
Biosynthesis of hyperforin in Hypericum perforatum
stated in
Studies on the antioxidative activity of phloroglucinol derivatives isolated from hypericum species
stated in
Bisanthraquinone glycosides of Hypericum perforatum with binding inhibition to CRH-1 receptors
stated in
Pharmaceutical Quality of Hypericum Extracts
stated in
Variability in the content of the constituents of Hypericum perforatum L. and some commercial extracts
stated in
Investigations on the Infraspecific Variability of Hypericum perforatum L.
Hypericaceae
1 reference
stated in
Hyperforin, an Anti-Inflammatory Constituent from St. John's Wort, Inhibits Microsomal Prostaglandin E(2) Synthase-1 and Suppresses Prostaglandin E(2) Formation in vivo
Hypericum barbatum
1 reference
stated in
Phytochemical analysis and genetic characterization of six Hypericum species from Serbia
Hypericum hirsutum
1 reference
stated in
Phytochemical analysis and genetic characterization of six Hypericum species from Serbia
Hypericum linarioides
1 reference
stated in
Phytochemical analysis and genetic characterization of six Hypericum species from Serbia
Hypericum maculatum
1 reference
stated in
Phytochemical analysis and genetic characterization of six Hypericum species from Serbia
Hypericum rumeliacum
1 reference
stated in
Phytochemical analysis and genetic characterization of six Hypericum species from Serbia
Hypericum tetrapterum
1 reference
stated in
Phytochemical analysis and genetic characterization of six Hypericum species from Serbia
Hypericum androsaemum
1 reference
stated in
Variability in phenolic composition of Hypericum androsaemum
Hypericum calycinum
2 references
stated in
The first prenylation step in hyperforin biosynthesis.
stated in
Biosynthesis of the hyperforin skeleton in Hypericum calycinum cell cultures
Hypericum grandifolium
1 reference
stated in
HPLC-MS analysis and anti-oedematogenic activity of Hypericum grandifolium Choisy (Hypericaceae).
Hypericum venustum
1 reference
stated in
Phenolic constituents and the in vitro antioxidant activity of the flowers of Hypericum venustum
Hypericum henryi
1 reference
stated in
Polycyclic Polyprenylated Acylphloroglucinol Congeners Possessing Diverse Structures from Hypericum henryi
Hypericum elodes
1 reference
stated in
Detection of hypericins in the "red glands" of Hypericum elodes by ESI-MS/MS.
mass
536.386560144
dalton
1 reference
based on heuristic
inferred from SMILES
said to be the same as
hyperforin
0 references
Commons category
Hyperforin
0 references
Identifiers
InChI
InChI=1S/C35H52O4/c1-22(2)13-12-19-33(11)27(16-14-23(3)4)21-34(20-18-25(7)8)30(37)28(17-15-24(5)6)31(38)35(33,32(34)39)29(36)26(9)10/h13-15,18,26-27,37H,12,16-17,19-21H2,1-11H3/t27-,33+,34+,35-/m0/s1
0 references
InChIKey
KGSZHKRKHXOAMG-HQKKAZOISA-N
0 references
CAS Registry Number
11079-53-1
1 reference
imported from Wikimedia project
German Wikipedia
ChemSpider ID
16736597
1 reference
imported from Wikimedia project
English Wikipedia
PubChem CID
441298
1 reference
matched by identifier from
InChIKey
InChIKey
KGSZHKRKHXOAMG-HQKKAZOISA-N
Reaxys registry number
6785663
0 references
ChEBI ID
5834
reason for deprecated rank
cannot be confirmed by other sources
1 reference
imported from Wikimedia project
English Wikipedia
SureChEMBL ID
15557965
1 reference
matched by identifier from
InChIKey
InChIKey
KGSZHKRKHXOAMG-HQKKAZOISA-N
UniChem compound ID
331103
1 reference
stated in
UniChem
HSDB ID
7646
1 reference
stated in
Hazardous Substances Data Bank
HSDB ID
7646
publication date
28 October 2019
title
HYPERFORIN
(English)
retrieved
10 May 2021
DSSTox substance ID
DTXSID90891409
0 references
DSSTOX compound identifier
DTXCID301030528
0 references
EC number
601-000-9
1 reference
stated in
ECHA Substance Infocard database
ECHA Substance Infocard ID
100.112.565
retrieved
27 December 2018
title
Bicyclo[3.3.1]non-3-ene-2,9-dione, 4-hydroxy-6-methyl-1,3,7-tris(3-methyl-2-buten-1-yl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-penten-1-yl)-, (1R,5S,6R,7S)-
(English)
quotation
CAS no.: 11079-53-1
(English)
ECHA Substance Infocard ID
100.112.565
1 reference
stated in
ECHA Substance Infocard database
ECHA Substance Infocard ID
100.112.565
retrieved
27 December 2018
title
Bicyclo[3.3.1]non-3-ene-2,9-dione, 4-hydroxy-6-methyl-1,3,7-tris(3-methyl-2-buten-1-yl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-penten-1-yl)-, (1R,5S,6R,7S)-
(English)
quotation
CAS no.: 11079-53-1
(English)
Nikkaji ID
J15.315J
1 reference
imported from Wikimedia project
Japanese Wikipedia
Wikimedia import URL
https://ja.wikipedia.org/w/index.php?title=ハイパフォリン&oldid=60368343
DrugBank ID
DB01892
0 references
Human Metabolome Database ID
HMDB0030463
0 references
KNApSAcK ID
C00034542
0 references
UNII
RM741E34FP
0 references
Probes And Drugs ID
PD015600
0 references
KEGG ID
C07608
1 reference
imported from Wikimedia project
English Wikipedia
Freebase ID
/m/043v8h
1 reference
stated in
Freebase Data Dumps
publication date
28 October 2013
Microsoft Academic ID
2778350159
0 references
NALT ID
46555
0 references
OpenAlex ID
C2778350159
1 reference
stated in
OpenAlex
retrieved
26 January 2022
reference URL
https://docs.openalex.org/download-snapshot/snapshot-data-format
Römpp online ID
RD-08-02589
1 reference
imported from Wikimedia project
German Wikipedia
Sitelinks
Wikipedia
(14 entries)
edit
azbwiki
هیپرفورین
dewiki
Hyperforin
enwiki
Hyperforin
eswiki
Hiperforina
fawiki
هیپرفورین
fiwiki
Hyperforiini
huwiki
Hiperforin
itwiki
Iperforina
jawiki
ハイパフォリン
plwiki
Hiperforyna
ruwiki
Гиперфорин
shwiki
Hiperforin
srwiki
Hiperforin
ukwiki
Гіперфорин
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(1 entry)
edit
commonswiki
Category:Hyperforin
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