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Biochemical and biological analysis of Mek1 phosphorylation site mutants
(Q34446879)
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English
Biochemical and biological analysis of Mek1 phosphorylation site mutants
scientific article
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
7612960
retrieved
2 August 2017
title
Biochemical and biological analysis of Mek1 phosphorylation site mutants
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
7612960
retrieved
2 August 2017
main subject
phosphorylation
1 reference
based on heuristic
inferred from title
author name string
W Huang
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
7612960
retrieved
2 August 2017
D S Kessler
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
7612960
retrieved
2 August 2017
R L Erikson
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
7612960
retrieved
2 August 2017
publication date
1 March 1995
1 reference
stated in
Europe PubMed Central
PubMed publication ID
7612960
retrieved
2 August 2017
published in
Molecular Biology of the Cell
1 reference
stated in
Europe PubMed Central
PubMed publication ID
7612960
retrieved
2 August 2017
volume
6
1 reference
stated in
Europe PubMed Central
PubMed publication ID
7612960
retrieved
2 August 2017
issue
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
7612960
retrieved
2 August 2017
page(s)
237-245
1 reference
stated in
Europe PubMed Central
PubMed publication ID
7612960
retrieved
2 August 2017
cites work
The cdc2-related protein p40MO15 is the catalytic subunit of a protein kinase that can activate p33cdk2 and p34cdc2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
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6 July 2018
Signal transduction via the MAP kinases: proceed at your own RSK.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
A conserved kinase cascade for MAP kinase activation in yeast.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Metabolic labeling of mitogen-activated protein kinase kinase in A431 cells demonstrates phosphorylation on serine and threonine residues
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEK1 and MEK2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Mos stimulates MAP kinase in Xenopus oocytes and activates a MAP kinase kinase in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Molecular structure of a protein-tyrosine/threonine kinase activating p42 mitogen-activated protein (MAP) kinase: MAP kinase kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
CAK, the p34cdc2 activating kinase, contains a protein identical or closely related to p40MO15.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
The MO15 gene encodes the catalytic subunit of a protein kinase that activates cdc2 and other cyclin-dependent kinases (CDKs) through phosphorylation of Thr161 and its homologues
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Requirement for Raf and MAP kinase function during the meiotic maturation of Xenopus oocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Mammalian Ras interacts directly with the serine/threonine kinase Raf
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
The mitogen-activated protein kinase signal transduction pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Raf-1 protein kinase is important for progesterone-induced Xenopus oocyte maturation and acts downstream of mos
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Raf-1 forms a stable complex with Mek1 and activates Mek1 by serine phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Mos induces the in vitro activation of mitogen-activated protein kinases in lysates of frog oocytes and mammalian somatic cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Requirement for the MAP kinase kinase/MAP kinase cascade in Xenopus oocyte maturation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Identification of the sites in MAP kinase kinase-1 phosphorylated by p74raf-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Activation of MEK family kinases requires phosphorylation of two conserved Ser/Thr residues.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Enzymatic characteristics of the c-Raf-1 protein kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Constitutive activation of Mek1 by mutation of serine phosphorylation sites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
A cyclin associated with the CDK-activating kinase MO15
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
A novel cyclin associates with MO15/CDK7 to form the CDK-activating kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Transformation of mammalian cells by constitutively active MAP kinase kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
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6 July 2018
Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Expression and activity of p40MO15, the catalytic subunit of cdk-activating kinase, during Xenopus oogenesis and embryogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Critical Tyrosine Residues Regulate the Enzymatic and Biological Activity of Raf-1 Kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
An osmosensing signal transduction pathway in yeast.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Nucleotide sequence of the yeast regulatory gene STE7 predicts a protein homologous to protein kinases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Purification of maturation-promoting factor, an intracellular regulator of early mitotic events
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
A gene which encodes a predicted protein kinase can restore some functions of the ras gene in fission yeast.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Function of c-mos proto-oncogene product in meiotic maturation in Xenopus oocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
A novel genetic system to detect protein-protein interactions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
byr2, a Schizosaccharomyces pombe gene encoding a protein kinase capable of partial suppression of the ras1 mutant phenotype
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
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6 July 2018
ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
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6 July 2018
Identification of substrate recognition determinants for human ERK1 and ERK2 protein kinases
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
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6 July 2018
Molecular cloning of a GTPase activating protein specific for the Krev-1 protein p21rap1
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
In vitro effects on microtubule dynamics of purified Xenopus M phase-activated MAP kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Order of action of components in the yeast pheromone response pathway revealed with a dominant allele of the STE11 kinase and the multiple phosphorylation of the STE7 kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Ordered phosphorylation of p42mapk by MAP kinase kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Meiotic initiation by the mos protein in Xenopus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Phorbol ester stimulates a protein-tyrosine/threonine kinase that phosphorylates and activates the Erk-1 gene product
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Erks: their fifteen minutes has arrived
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Activation of the MAP kinase pathway by the protein kinase raf
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Activation of mitogen-activated protein kinase kinase by v-Raf in NIH 3T3 cells and in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Raf-1 activates MAP kinase-kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
The phorbol ester-dependent activator of the mitogen-activated protein kinase p42mapk is a kinase with specificity for the threonine and tyrosine regulatory sites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Xenopus MAP kinase activator: identification and function as a key intermediate in the phosphorylation cascade
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
A purified S6 kinase kinase from Xenopus eggs activates S6 kinase II and autophosphorylates on serine, threonine, and tyrosine residues
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
Human T-cell mitogen-activated protein kinase kinases are related to yeast signal transduction kinases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
6 July 2018
MEK2 is a kinase related to MEK1 and is differentially expressed in murine tissues.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
27 October 2018
An osmosensing signal transduction pathway in mammalian cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
27 October 2018
Action of progesterone and related steroids on oocyte maturation in Xenopus laevis. An in vitro study
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=301184
retrieved
27 October 2018
Dissection of the protein kinase cascade by which nerve growth factor activates MAP kinases
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/7612960
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1091/MBC.6.3.237
1 reference
stated in
Europe PubMed Central
PubMed publication ID
7612960
retrieved
2 August 2017
PMC publication ID
301184
1 reference
stated in
Europe PubMed Central
PubMed publication ID
7612960
retrieved
2 August 2017
PubMed publication ID
7612960
1 reference
stated in
Europe PubMed Central
PubMed publication ID
7612960
retrieved
2 August 2017
ResearchGate publication ID
15586105
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