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Attenuation of the norepinephrine transporter activity and trafficking via interactions with alpha-synuclein(Q24323344)

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English	Attenuation of the norepinephrine transporter activity and trafficking via interactions with alpha-synuclein	scientific article

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Attenuation of the norepinephrine transporter activity and trafficking via interactions with alpha-synuclein(English)

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Synuclein alpha

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GOA release 2020-03-11

negative regulation of norepinephrine uptake

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GOA release 2020-03-11

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author name string

Christophe Wersinger

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Alexis Jeannotte

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Anita Sidhu

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publication date

December 2006

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language of work or name

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European Journal of Neuroscience

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24

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11

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3141-52

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Role of serotonergic and noradrenergic systems in the pathophysiology of depression and anxiety disorders

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Ultrastructural localization of the norepinephrine transporter in superficial and deep layers of the rat prelimbic prefrontal cortex and its spatial relationship to probable dopamine terminals

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Circuits and systems in stress. I. Preclinical studies

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Immunolocalization of the cocaine- and antidepressant-sensitive l-norepinephrine transporter

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Neurochemical interaction between dopaminergic and noradrenergic neurons in the medial prefrontal cortex

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Localization and dynamic regulation of biogenic amine transporters in the mammalian central nervous system

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Pathology of Parkinson's disease. Changes other than the nigrostriatal pathway

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The locus coeruleus: neurobiology of a central noradrenergic nucleus

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Proteomic analysis of human norepinephrine transporter complexes reveals associations with protein phosphatase 2A anchoring subunit and 14-3-3 proteins

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Noradrenergic mechanisms in neurodegenerative diseases: a theory

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Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration

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Snaring the function of alpha-synuclein

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alpha-Synuclein regulation of the dopaminergic transporter: a possible role in the pathogenesis of Parkinson's disease

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Comparative analyses of alpha-synuclein expression levels in rat brain tissues and transfected cells

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Genetic deletion of the norepinephrine transporter decreases vulnerability to seizures

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Brain substrates for increased drug seeking during protracted withdrawal

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The role of alpha-synuclein in neurodegenerative diseases

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Ca(2+)-dependent enhancement of [3H]noradrenaline uptake in PC12 cells through calmodulin-dependent kinases

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Section III. The norepinephrine system

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Biosynthesis, N-glycosylation, and surface trafficking of biogenic amine transporter proteins

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Locus coeruleus and regulation of behavioral flexibility and attention

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The role of the locus coeruleus in the development of Parkinson's disease

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Chronic and acute regulation of Na+/Cl–-dependent neurotransmitter transporters: drugs, substrates, presynaptic receptors, and signaling systems

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The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease

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Attenuation of dopamine transporter activity by alpha-synuclein

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Differential localization of alpha-, beta- and gamma-synucleins in the rat CNS

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Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1

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Mutations in the lipid-binding domain of α-synuclein confer overlapping, yet distinct, functional properties in the regulation of dopamine transporter activity

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Trypsin disrupts the trafficking of the human dopamine transporter by alpha-synuclein and its A30P mutant

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Disruption of the interaction of alpha-synuclein with microtubules enhances cell surface recruitment of the dopamine transporter

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Expression cloning of a cocaine- and antidepressant-sensitive human noradrenaline transporter

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Plasma membrane monoamine transporters: structure, regulation and function

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The role of alpha-synuclein in Parkinson's disease: insights from animal models

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Pathogenesis of Parkinson's disease: dopamine, vesicles and alpha-synuclein

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Intravenous cocaine induced-activity and behavioural sensitization in norepinephrine-, but not dopamine-transporter knockout mice

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Distribution of α‐ and γ‐synucleins in the adult rat brain and their modification by high‐dose cocaine treatment

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Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation.

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Regulated internalization and phosphorylation of the native norepinephrine transporter in response to phorbol esters. Evidence for localization in lipid rafts and lipid raft-mediated internalization

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A combinatorial code for the interaction of alpha-synuclein with membranes

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Lipid rafts mediate the synaptic localization of alpha-synuclein.

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10.1111/J.1460-9568.2006.05181.X

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