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Delayed transactivation of the receptor for nerve growth factor is required for sustained signaling and differentiation by alpha2-adrenergic receptors in transfected PC12 cells(Q24292770)

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English	Delayed transactivation of the receptor for nerve growth factor is required for sustained signaling and differentiation by alpha2-adrenergic receptors in transfected PC12 cells	scientific article

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Delayed transactivation of the receptor for nerve growth factor is required for sustained signaling and differentiation by alpha2-adrenergic receptors in transfected PC12 cells(English)

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Adrenoceptor alpha 2B

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GOA release 2020-03-11

Adrenoceptor alpha 2C

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GOA release 2020-03-11

Adrenoceptor alpha 2A

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GOA release 2020-03-11

adrenergic receptor signaling pathway

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GOA release 2020-03-11

author name string

Georgios Karkoulias

1

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Christodoulos Flordellis

2

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language of work or name

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publication date

May 2007

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Cellular Signalling

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19

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5

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945-57

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Neuronal differentiation signals are controlled by nerve growth factor receptor/Trk binding sites for SHC and PLC gamma.

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Different mechanisms for inhibition of cell proliferation via cell cycle proteins in PC12 cells by nerve growth factor and staurosporine

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A radioactive binding assay for inhibitors of trkA kinase

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WAF1, a potential mediator of p53 tumor suppression

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A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein beta gamma subunits

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Trk receptors use redundant signal transduction pathways involving SHC and PLC-gamma 1 to mediate NGF responses

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alpha(2)-Adrenergic receptors activate MAPK and Akt through a pathway involving arachidonic acid metabolism by cytochrome P450-dependent epoxygenase, matrix metalloproteinase activation and subtype-specific transactivation of EGFR.

1 reference

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Localization and trafficking of alpha2-adrenergic receptor subtypes in cells and tissues

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Central adenosine A(2A) receptors: an overview

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Two alpha(2)-adrenergic receptor subtypes, alpha(2A) and alpha(2C), inhibit transmitter release in the brain of gene-targeted mice

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d-amphetamine and l-5-hydroxytryptophan-induced behaviours in mice with genetically-altered expression of the α2C-adrenergic receptor subtype

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EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor

1 reference

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Ras-dependent activation of MAP kinase pathway mediated by G-protein beta gamma subunits.

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Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

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EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF

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Alpha2A-adrenoceptors are important modulators of the effects of D-amphetamine on startle reactivity and brain monoamines

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Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor

1 reference

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Activation of Trk neurotrophin receptors in the absence of neurotrophins

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Cell cycle arrest mediated by the MEK/mitogen-activated protein kinase pathway

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Constitutive overexpression of CDK2 inhibits neuronal differentiation of rat pheochromocytoma PC12 cells

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Gbetagamma subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated Ras activation

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Differential Coupling of α1-, α2-, and β-Adrenergic Receptors to Mitogen-activated Protein Kinase Pathways and Differentiation in Transfected PC12 Cells

1 reference

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Activation of Trk neurotrophin receptor signaling by pituitary adenylate cyclase-activating polypeptides

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Cyclic AMP induces transactivation of the receptors for epidermal growth factor and nerve growth factor, thereby modulating activation of MAP kinase, Akt, and neurite outgrowth in PC12 cells

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Subtype-specific neuronal differentiation of PC12 cells transfected with alpha2-adrenergic receptors

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Signal characteristics of G protein-transactivated EGF receptor

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Relationship Between the Nerve Growth Factor-Regulated Clone 73 Gene Product and the 58-Kilodalton Neuronal Intermediate Filament Protein (Peripherin)

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1 reference

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1 reference

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p21--negative regulator of the cell cycle

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1 reference

14 December 2024

https://opencitations.net/index/api/v1/citations/10.1016/S0165-6147(97)01063-8

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10.1016/J.CELLSIG.2006.11.003

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