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sodium voltage-gated channel alpha subunit 1(Q21126314)

From Wikidata

mammalian protein found in Homo sapiens

sodium channel voltage gated type 1 alpha subunit
sodium channel protein type 1 subunit alpha
SCN1A
voltage-gated sodium channel subunit alpha Nav1.1
sodium channel protein, brain I alpha subunit
sodium channel, voltage-gated, type I, alpha subunit
sodium channel protein type I subunit alpha
sodium channel, voltage-gated, type I, alpha polypeptide
Sodium channel protein brain I subunit alpha
NAV1.1 Voltage-Gated Sodium Channel

Language	Label	Description	Also known as
default for all languages	No label defined
English	sodium voltage-gated channel alpha subunit 1	mammalian protein found in Homo sapiens	sodium channel voltage gated type 1 alpha subunit sodium channel protein type 1 subunit alpha SCN1A voltage-gated sodium channel subunit alpha Nav1.1 sodium channel protein, brain I alpha subunit sodium channel, voltage-gated, type I, alpha subunit sodium channel protein type I subunit alpha sodium channel, voltage-gated, type I, alpha polypeptide Sodium channel protein brain I subunit alpha NAV1.1 Voltage-Gated Sodium Channel

Statements

1 reference

13 November 2019

UniProt protein ID

Voltage gated sodium channel, alpha-1 subunit

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P35498

Voltage-dependent channel domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P35498

Voltage gated sodium channel

1 reference

Transporter Classification Database ID

2 October 2019

based on heuristic

hierarchical database ID heuristic

Sodium ion transport-associated domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ion transport domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Voltage-gated Na+ ion channel, cytoplasmic domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

sodium channel activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

voltage-gated ion channel activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

ion channel activity

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

voltage-gated sodium channel activity

determination method or standard

5 references

8 April 2019

Mutations of SCN1A, encoding a neuronal sodium channel, in two families with GEFS+2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

voltage-gated sodium channel complex

determination method or standard

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35498&geneProductId=UniProtKB:P35498

determination method or standard

integral component of membrane

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

determination method or standard

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

determination method or standard

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

plasma membrane

determination method or standard

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

determination method or standard

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

intercalated disc

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

determination method or standard

2 references

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

determination method or standard

1 reference

16 July 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35498&geneProductId=UniProtKB:P35498

determination method or standard

node of Ranvier

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

sodium channel complex

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

axon initial segment

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

voltage-gated sodium channel complex

determination method or standard

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

determination method or standard

2 references

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

biological process

membrane depolarization during action potential

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

sodium ion transmembrane transport

determination method or standard

1 reference

16 July 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35498&geneProductId=UniProtKB:P35498

determination method or standard

regulation of ion transmembrane transport

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

determination method or standard

2 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

transmembrane transport

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

ion transmembrane transport

determination method or standard

1 reference

16 July 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P35498&geneProductId=UniProtKB:P35498

determination method or standard

sodium ion transport

determination method or standard

5 references

8 April 2019

Mutations of SCN1A, encoding a neuronal sodium channel, in two families with GEFS+2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

cardiac muscle cell action potential involved in contraction

determination method or standard

1 reference

8 April 2019

Variants of Transient Receptor Potential Melastatin Member 4 in Childhood Atrioventricular Block

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

action potential

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

adult walking behavior

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

neuronal action potential propagation

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

neuronal action potential

determination method or standard

2 references

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

regulation of membrane potential

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

neuromuscular process controlling posture

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

detection of mechanical stimulus involved in sensory perception of pain

determination method or standard

2 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

sodium ion transmembrane transport

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35498

determination method or standard

physically interacts with

channel blocker

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

object of statement has role

channel blocker

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL861

object of statement has role

channel blocker

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1201242

object of statement has role

channel blocker

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1200

object of statement has role

channel blocker

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1068

object of statement has role

channel blocker

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL29741

dichlorobenzyl alcohol

object of statement has role

channel blocker

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL3184437

object of statement has role

channel blocker

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL2107771

object of statement has role

channel blocker

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL3678076

object of statement has role

channel blocker

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL79

object of statement has role

channel blocker

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL750

object of statement has role

channel blocker

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL220492

chloroprocaine hydrochloride

object of statement has role

channel blocker

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL944

eslicarbazepine

object of statement has role

channel blocker

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL315985

quinidine gluconate

object of statement has role

channel blocker

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1200437

disopyramide phosphate

object of statement has role

channel blocker

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1201020

dyclonine hydrochloride

object of statement has role

channel blocker

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1200478

mepivacaine hydrochloride

object of statement has role

channel blocker

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1200440

(RS)-mexiletine hydrochloride

object of statement has role

channel blocker

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1200606

orphenadrine citrate

object of statement has role

channel blocker

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1200395

procainamide hydrochloride

object of statement has role

channel blocker

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL605

propafenone hydrochloride

object of statement has role

channel blocker

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1201063

benoxinate hydrochloride

object of statement has role

channel blocker

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1200654

prilocaine hydrochloride

object of statement has role

channel blocker

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1200586

http://purl.uniprot.org/uniprot/P35498

1 reference

Identifiers.org

Voltage-gated Na+ ion channel, cytoplasmic domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P35498

Ion transport domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P35498

Sodium ion transport-associated

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P35498

Identifiers

MeSH descriptor ID

subject named as

NAV1.1 Voltage-Gated Sodium Channel

0 references

D12.776.157.530.400.875.750.100

0 references

D12.776.543.550.450.875.750.100

0 references

D12.776.543.585.400.875.750.100

0 references

D12.776.631.960.100

0 references

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000303540

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000303540

ENSP00000364554

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000364554

ENSP00000386312

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000386312

ENSP00000489986

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000489986

ENSP00000490184

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000490184

ENSP00000490288

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000490288

ENSP00000490612

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000490612

ENSP00000490692

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000490692

ENSP00000490780

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000490780

ENSP00000490799

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000490799

ENSP00000490895

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000490895

ENSP00000491573

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000491573

ENSP00000493054

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000493054

ENSP00000492945

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000492945

ENSP00000492917

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000492917

ENSP00000500336

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000500336

PDB structure ID

0 references

Transporter Classification Database ID

2 references

Transporter Classification database

13 March 2020

Transporter Classification database

29 April 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q21126314&oldid=2023008737"

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