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Glutamate ionotropic receptor NMDA type subunit 3A(Q21118868)

From Wikidata

mammalian protein found in Homo sapiens

NMDAR3A
GRIN3A
NMDAR-L
glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
glutamate receptor ionotropic, NMDA 3A
NR3A
glutamate [NMDA] receptor subunit 3A
N-methyl-D-aspartate receptor subtype 3A

Language	Label	Description	Also known as
default for all languages	No label defined
English	Glutamate ionotropic receptor NMDA type subunit 3A	mammalian protein found in Homo sapiens	NMDAR3A GRIN3A NMDAR-L glutamate receptor, ionotropic, N-methyl-D-aspartate 3A glutamate receptor ionotropic, NMDA 3A NR3A glutamate [NMDA] receptor subunit 3A N-methyl-D-aspartate receptor subtype 3A

Statements

1 reference

13 November 2019

UniProt protein ID

Periplasmic binding protein-like I

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8TCU5

ionotropic glutamate receptor, metazoa

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8TCU5

0 references

Ionotropic glutamate receptor domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ionotropic glutamate receptor, L-glutamate and glycine-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

glycine binding

determination method or standard

1 reference

8 April 2019

Characterisation of the human NMDA receptor subunit NR3A glycine binding site

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

identical protein binding

determination method or standard

1 reference

8 April 2019

Analysis of NR3A receptor subunits in human native NMDA receptors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

protein phosphatase 2A binding

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

ion channel activity

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

extracellularly glutamate-gated ion channel activity

determination method or standard

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8TCU5&geneProductId=UniProtKB:Q8TCU5

determination method or standard

calcium channel activity

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

ionotropic glutamate receptor activity

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

protein binding

determination method or standard

2 references

8 April 2019

Analysis of NR3A receptor subunits in human native NMDA receptors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

8 April 2019

The NMDAR subunit NR3A interacts with microtubule-associated protein 1S in the brain

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

NMDA glutamate receptor activity

determination method or standard

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

8 April 2019

Pharmacological characterization of glycine-activated currents in HEK 293 cells expressing N-methyl-D-aspartate NR1 and NR3 subunits

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

signaling receptor activity

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

determination method or standard

2 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

8 April 2019

The NMDAR subunit NR3A interacts with microtubule-associated protein 1S in the brain

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

integral component of membrane

determination method or standard

2 references

8 April 2019

Cloning and expression of the human N-methyl-D-aspartate receptor subunit NR3A

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

NMDA selective glutamate receptor complex

determination method or standard

1 reference

8 April 2019

Analysis of NR3A receptor subunits in human native NMDA receptors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

neuron projection

determination method or standard

1 reference

8 April 2019

The NMDAR subunit NR3A interacts with microtubule-associated protein 1S in the brain

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

postsynaptic density

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

postsynaptic membrane

determination method or standard

2 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

determination method or standard

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

8 April 2019

Analysis of NR3A receptor subunits in human native NMDA receptors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

determination method or standard

2 references

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

8 April 2019

The NMDAR subunit NR3A interacts with microtubule-associated protein 1S in the brain

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

plasma membrane

determination method or standard

1 reference

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8TCU5&geneProductId=UniProtKB:Q8TCU5

determination method or standard

plasma membrane

determination method or standard

2 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

glutamatergic synapse

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

biological process

calcium ion transport

determination method or standard

2 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

dendrite development

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

response to ethanol

determination method or standard

2 references

8 April 2019

Enhanced ethanol inhibition of recombinant N-methyl-D-aspartate receptors by magnesium: role of NR3A subunits

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

8 April 2019

Pharmacological characterization of glycine-activated currents in HEK 293 cells expressing N-methyl-D-aspartate NR1 and NR3 subunits

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

prepulse inhibition

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

determination method or standard

2 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

calcium ion transmembrane transport

determination method or standard

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

ionotropic glutamate receptor signaling pathway

determination method or standard

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

ion transmembrane transport

determination method or standard

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

excitatory postsynaptic potential

determination method or standard

1 reference

27 March 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8TCU5&geneProductId=UniProtKB:Q8TCU5

determination method or standard

signal transduction

determination method or standard

1 reference

27 March 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8TCU5&geneProductId=UniProtKB:Q8TCU5

determination method or standard

regulation of postsynaptic membrane potential

determination method or standard

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

regulation of synaptic vesicle exocytosis

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TCU5

determination method or standard

physically interacts with

object of statement has role

channel blocker

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL467084

object of statement has role

positive allosteric modullator

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1255840

object of statement has role

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL2107771

object of statement has role

negative allosteric modulator

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL395091

object of statement has role

negative allosteric modulator

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL742

object of statement has role

channel blocker

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL41306

ketamine hydrochloride

object of statement has role

negative allosteric modulator

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1714

amantadine hydrochloride

object of statement has role

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1569

orphenadrine citrate

object of statement has role

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1200395

Ionotropic glutamate receptor domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8TCU5

Ionotropic glutamate receptor, L-glutamate and glycine-binding domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8TCU5

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000355155

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000355155

Transporter Classification Database ID

1 reference

based on heuristic

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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