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Glutamate ionotropic receptor NMDA type subunit 2B(Q21115816)

From Wikidata

mammalian protein found in Homo sapiens

glutamate receptor subunit epsilon-2
glutamate [NMDA] receptor subunit epsilon-2
N-methyl-D-aspartate receptor subunit 3
NMDAR2B
GRIN2B
N-methyl D-aspartate receptor subtype 2B
NR2B
hNR3
NR3
glutamate receptor ionotropic, NMDA 2B
glutamate receptor, ionotropic, N-methyl D-aspartate 2B

Language	Label	Description	Also known as
default for all languages	No label defined
English	Glutamate ionotropic receptor NMDA type subunit 2B	mammalian protein found in Homo sapiens	glutamate receptor subunit epsilon-2 glutamate [NMDA] receptor subunit epsilon-2 N-methyl-D-aspartate receptor subunit 3 NMDAR2B GRIN2B N-methyl D-aspartate receptor subtype 2B NR2B hNR3 NR3 glutamate receptor ionotropic, NMDA 2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B

Statements

1 reference

13 November 2019

UniProt protein ID

Periplasmic binding protein-like I

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q13224

ionotropic glutamate receptor, metazoa

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q13224

0 references

Receptor, ligand binding region, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ionotropic glutamate receptor domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Glutamate [NMDA] receptor, epsilon subunit, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ionotropic glutamate receptor, L-glutamate and glycine-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

zinc ion binding

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

glycine binding

determination method or standard

1 reference

8 April 2019

Subunit-specific roles of glycine-binding domains in activation of NR1/NR3 N-methyl-D-aspartate receptors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

metal ion binding

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

ion channel activity

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

protein binding

determination method or standard

8 references

8 April 2019

Analysis of NR3A receptor subunits in human native NMDA receptors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

8 April 2019

A Novel Human CAMK2A Mutation Disrupts Dendritic Morphology and Synaptic Transmission, and Causes ASD-Related Behaviors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

8 April 2019

Subunit-specific roles of glycine-binding domains in activation of NR1/NR3 N-methyl-D-aspartate receptors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

8 April 2019

Proteome-wide analysis of phospho-regulated PDZ domain interactions

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

8 April 2019

Identification of a small-molecule inhibitor of the PICK1 PDZ domain that inhibits hippocampal LTP and LTD.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

8 April 2019

Large-scale interaction profiling of PDZ domains through proteomic peptide-phage display using human and viral phage peptidomes

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

8 April 2019

Phosphorylation status of the NR2B subunit of NMDA receptor regulates its interaction with calcium/calmodulin-dependent protein kinase II

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

8 April 2019

Selectivity and promiscuity of the first and second PDZ domains of PSD-95 and synapse-associated protein 102

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

ionotropic glutamate receptor activity

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

extracellularly glutamate-gated ion channel activity

determination method or standard

1 reference

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13224&geneProductId=UniProtKB:Q13224

determination method or standard

NMDA glutamate receptor activity

determination method or standard

3 references

31 October 2017

Cloning and functional characterization of human heteromeric N-methyl-D-aspartate receptors

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13224&geneProductId=UniProtKB:Q13224

determination method or standard

31 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13224&geneProductId=UniProtKB:Q13224

determination method or standard

31 October 2017

Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13224&geneProductId=UniProtKB:Q13224

determination method or standard

glutamate binding

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

glutamate-gated calcium ion channel activity

determination method or standard

2 references

8 April 2019

Mechanistic Insight into NMDA Receptor Dysregulation by Rare Variants in the GluN2A and GluN2B Agonist Binding Domains

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

8 April 2019

Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

amyloid-beta binding

determination method or standard

1 reference

8 April 2019

Amyloid-β Receptors: The Good, the Bad, and the Prion Protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

NMDA glutamate receptor activity

determination method or standard

5 references

8 April 2019

Cloning and functional characterization of human heteromeric N-methyl-D-aspartate receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

8 April 2019

Fyn-mediated phosphorylation of NR2B Tyr-1336 controls calpain-mediated NR2B cleavage in neurons and heterologous systems

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

8 April 2019

Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

signaling receptor activity

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

integral component of membrane

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

postsynaptic membrane

determination method or standard

1 reference

31 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13224&geneProductId=UniProtKB:Q13224

determination method or standard

determination method or standard

2 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

NMDA selective glutamate receptor complex

determination method or standard

4 references

31 October 2017

Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13224&geneProductId=UniProtKB:Q13224

determination method or standard

31 October 2017

Subunit-specific roles of glycine-binding domains in activation of NR1/NR3 N-methyl-D-aspartate receptors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13224&geneProductId=UniProtKB:Q13224

determination method or standard

31 October 2017

Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13224&geneProductId=UniProtKB:Q13224

determination method or standard

31 October 2017

Biochemical evidence for the co-association of three N-methyl-D-aspartate (NMDA) R2 subunits in recombinant NMDA receptors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13224&geneProductId=UniProtKB:Q13224

determination method or standard

determination method or standard

2 references

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

8 April 2019

Fyn-mediated phosphorylation of NR2B Tyr-1336 controls calpain-mediated NR2B cleavage in neurons and heterologous systems

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

neuron projection

determination method or standard

1 reference

8 April 2019

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

intracellular anatomical structure

determination method or standard

1 reference

31 October 2017

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13224&geneProductId=UniProtKB:Q13224

determination method or standard

integral component of plasma membrane

determination method or standard

3 references

8 April 2019

Cloning and functional characterization of human heteromeric N-methyl-D-aspartate receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

8 April 2019

Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

8 April 2019

Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

postsynaptic density

determination method or standard

2 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

plasma membrane

determination method or standard

3 references

31 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13224&geneProductId=UniProtKB:Q13224

determination method or standard

31 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13224&geneProductId=UniProtKB:Q13224

determination method or standard

31 October 2017

Mechanistic Insight into NMDA Receptor Dysregulation by Rare Variants in the GluN2A and GluN2B Agonist Binding Domains

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13224&geneProductId=UniProtKB:Q13224

determination method or standard

determination method or standard

1 reference

8 April 2019

Fyn-mediated phosphorylation of NR2B Tyr-1336 controls calpain-mediated NR2B cleavage in neurons and heterologous systems

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

plasma membrane

determination method or standard

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

8 April 2019

Mechanistic Insight into NMDA Receptor Dysregulation by Rare Variants in the GluN2A and GluN2B Agonist Binding Domains

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

NMDA selective glutamate receptor complex

determination method or standard

6 references

8 April 2019

Fyn-mediated phosphorylation of NR2B Tyr-1336 controls calpain-mediated NR2B cleavage in neurons and heterologous systems

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

8 April 2019

Biochemical evidence for the co-association of three N-methyl-D-aspartate (NMDA) R2 subunits in recombinant NMDA receptors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

8 April 2019

Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

8 April 2019

Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

8 April 2019

Subunit-specific roles of glycine-binding domains in activation of NR1/NR3 N-methyl-D-aspartate receptors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

postsynaptic membrane

determination method or standard

2 references

8 April 2019

Memory enhancement by targeting Cdk5 regulation of NR2B.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

synaptic membrane

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

postsynaptic density membrane

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

biological process

glutamate receptor signaling pathway

determination method or standard

1 reference

8 April 2019

Cloning and functional characterization of human heteromeric N-methyl-D-aspartate receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

ephrin receptor signaling pathway

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

determination method or standard

2 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

learning or memory

determination method or standard

1 reference

31 October 2017

Genetic enhancement of learning and memory in mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13224&geneProductId=UniProtKB:Q13224

determination method or standard

response to ethanol

determination method or standard

1 reference

8 April 2019

Enhanced ethanol inhibition of recombinant N-methyl-D-aspartate receptors by magnesium: role of NR3A subunits

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

chemical synaptic transmission

determination method or standard

1 reference

8 April 2019

Genetic enhancement of learning and memory in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

ionotropic glutamate receptor signaling pathway

determination method or standard

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

excitatory postsynaptic potential

determination method or standard

1 reference

31 October 2017

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13224&geneProductId=UniProtKB:Q13224

determination method or standard

regulation of ion transmembrane transport

determination method or standard

1 reference

31 October 2017

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13224&geneProductId=UniProtKB:Q13224

determination method or standard

determination method or standard

2 references

31 October 2017

Cloning and functional characterization of human heteromeric N-methyl-D-aspartate receptors

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13224&geneProductId=UniProtKB:Q13224

determination method or standard

31 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13224&geneProductId=UniProtKB:Q13224

determination method or standard

calcium-mediated signaling

determination method or standard

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

protein heterotetramerization

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

regulation of molecular function

determination method or standard

1 reference

31 October 2017

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13224&geneProductId=UniProtKB:Q13224

determination method or standard

calcium ion transmembrane import into cytosol

determination method or standard

2 references

8 April 2019

Mechanistic Insight into NMDA Receptor Dysregulation by Rare Variants in the GluN2A and GluN2B Agonist Binding Domains

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

8 April 2019

Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

multicellular organism development

determination method or standard

1 reference

8 April 2019

Fyn-mediated phosphorylation of NR2B Tyr-1336 controls calpain-mediated NR2B cleavage in neurons and heterologous systems

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

brain development

determination method or standard

1 reference

8 April 2019

Fyn-mediated phosphorylation of NR2B Tyr-1336 controls calpain-mediated NR2B cleavage in neurons and heterologous systems

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

learning or memory

determination method or standard

2 references

8 April 2019

Genetic enhancement of learning and memory in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

regulation of synaptic plasticity

determination method or standard

1 reference

8 April 2019

Fyn-mediated phosphorylation of NR2B Tyr-1336 controls calpain-mediated NR2B cleavage in neurons and heterologous systems

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

excitatory postsynaptic potential

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

long-term potentiation

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

excitatory chemical synaptic transmission

determination method or standard

1 reference

8 April 2019

Fyn-mediated phosphorylation of NR2B Tyr-1336 controls calpain-mediated NR2B cleavage in neurons and heterologous systems

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

positive regulation of neuron death

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

negative regulation of dendritic spine maintenance

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

positive regulation of cysteine-type endopeptidase activity

determination method or standard

1 reference

8 April 2019

Fyn-mediated phosphorylation of NR2B Tyr-1336 controls calpain-mediated NR2B cleavage in neurons and heterologous systems

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

regulation of NMDA receptor activity

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13224

determination method or standard

physically interacts with

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

L-aspartic acid

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

homoquinolinic acid

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

Tetrazolylglycine

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

N-methyl-D-aspartic acid

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

5,7-dichlorokynurenic acid

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

channel blocker

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

channel blocker

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

channel blocker

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

channel blocker

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

object of statement has role

channel blocker

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL467084

object of statement has role

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL2068839

object of statement has role

positive allosteric modullator

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1255840

object of statement has role

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL2107771

object of statement has role

negative allosteric modulator

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL395091

object of statement has role

negative allosteric modulator

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL742

object of statement has role

channel blocker

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL41306

ketamine hydrochloride

object of statement has role

negative allosteric modulator

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1714

amantadine hydrochloride

object of statement has role

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1569

orphenadrine citrate

object of statement has role

1 reference

Open Targets Platform

14 August 2023

https://platform.opentargets.org/drug/CHEMBL1200395

Ionotropic glutamate receptor, L-glutamate and glycine-binding domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q13224

Glutamate [NMDA] receptor, epsilon subunit, C-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q13224

Receptor, ligand binding region

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q13224

Ionotropic glutamate receptor domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q13224

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000477455

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000477455

ENSP00000486411

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000486411

ENSP00000486677

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000486677

ENSP00000489997

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000489997

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Transporter Classification Database ID

1 reference

based on heuristic

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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