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5-hydroxytryptamine receptor 2C
(Q21108118)
Item
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From Wikidata
mammalian protein found in Homo sapiens
serotonin 5-HT-2C receptor
5-HT-1C
5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTR2C
serotonin 5-HT-1C receptor
5-hydroxytryptamine receptor 1C
Serotonin receptor 2C
5-HT1C
edit
Language
Label
Description
Also known as
default for all languages
No label defined
–
English
5-hydroxytryptamine receptor 2C
mammalian protein found in Homo sapiens
serotonin 5-HT-2C receptor
5-HT-1C
5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTR2C
serotonin 5-HT-1C receptor
5-hydroxytryptamine receptor 1C
Serotonin receptor 2C
5-HT1C
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P28335
part of
5-hydroxytryptamine 2C receptor
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P28335
GPCR, rhodopsin-like, 7TM, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P28335
encoded by
HTR2C
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P28335
molecular function
1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding
determination method or standard
IDA
1 reference
retrieved
8 April 2019
stated in
Pharmacological characterization of mitogen-activated protein kinase activation by recombinant human 5-HT2C, 5-HT2A, and 5-HT2B receptors
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IDA
G protein-coupled receptor activity
determination method or standard
IEA
2 references
retrieved
21 June 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P28335&geneProductId=UniProtKB:P28335
determination method or standard
IEA
retrieved
21 June 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P28335&geneProductId=UniProtKB:P28335
determination method or standard
IEA
signal transducer activity
determination method or standard
IEA
1 reference
retrieved
1 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P28335&geneProductId=UniProtKB:P28335
determination method or standard
IEA
G protein-coupled serotonin receptor activity
determination method or standard
IDA
IEA
3 references
retrieved
21 June 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P28335&geneProductId=UniProtKB:P28335
determination method or standard
IEA
retrieved
21 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P28335&geneProductId=UniProtKB:P28335
determination method or standard
IEA
retrieved
21 June 2018
stated in
The pharmacology and distribution of human 5‐hydroxytryptamine2B (5‐HT2b) receptor gene products: comparison with 5‐HT2a and 5‐HT2c receptors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P28335&geneProductId=UniProtKB:P28335
determination method or standard
IDA
Gq/11-coupled serotonin receptor activity
determination method or standard
IDA
1 reference
retrieved
8 April 2019
stated in
Agonist-directed trafficking of signalling at serotonin 5-HT2A, 5-HT2B and 5-HT2C-VSV receptors mediated Gq/11 activation and calcium mobilisation in CHO cells
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IDA
serotonin binding
determination method or standard
IDA
3 references
retrieved
8 April 2019
stated in
Molecular determinants for the interaction of the valvulopathic anorexigen norfenfluramine with the 5-HT2B receptor
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IDA
retrieved
8 April 2019
stated in
Pharmacological characterization of mitogen-activated protein kinase activation by recombinant human 5-HT2C, 5-HT2A, and 5-HT2B receptors
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IDA
retrieved
8 April 2019
stated in
The pharmacology and distribution of human 5‐hydroxytryptamine2B (5‐HT2b) receptor gene products: comparison with 5‐HT2a and 5‐HT2c receptors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IDA
neurotransmitter receptor activity
determination method or standard
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IBA
G protein-coupled receptor activity
determination method or standard
IBA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IBA
G protein-coupled serotonin receptor activity
determination method or standard
IBA
IDA
IEA
4 references
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IEA
retrieved
8 April 2019
stated in
The pharmacology and distribution of human 5‐hydroxytryptamine2B (5‐HT2b) receptor gene products: comparison with 5‐HT2a and 5‐HT2c receptors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IBA
cell component
integral component of membrane
determination method or standard
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IEA
membrane
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IEA
plasma membrane
determination method or standard
IDA
TAS
IEA
4 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IEA
retrieved
8 April 2019
stated in
Agonist-directed trafficking of signalling at serotonin 5-HT2A, 5-HT2B and 5-HT2C-VSV receptors mediated Gq/11 activation and calcium mobilisation in CHO cells
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IDA
retrieved
8 April 2019
stated in
Agonist actions of dihydroergotamine at 5-HT2B and 5-HT2C receptors and their possible relevance to antimigraine efficacy
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IDA
integral component of plasma membrane
determination method or standard
IEA
IMP
2 references
retrieved
21 June 2018
stated in
Agonist-directed trafficking of signalling at serotonin 5-HT2A, 5-HT2B and 5-HT2C-VSV receptors mediated Gq/11 activation and calcium mobilisation in CHO cells
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P28335&geneProductId=UniProtKB:P28335
determination method or standard
IMP
retrieved
21 June 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P28335&geneProductId=UniProtKB:P28335
determination method or standard
IEA
intracellular anatomical structure
determination method or standard
IEA
1 reference
retrieved
10 September 2018
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P28335&geneProductId=UniProtKB:P28335
determination method or standard
IEA
integral component of plasma membrane
determination method or standard
IBA
IEA
IMP
3 references
retrieved
8 April 2019
stated in
Agonist-directed trafficking of signalling at serotonin 5-HT2A, 5-HT2B and 5-HT2C-VSV receptors mediated Gq/11 activation and calcium mobilisation in CHO cells
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IMP
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IBA
dendrite
determination method or standard
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IBA
biological process
release of sequestered calcium ion into cytosol
determination method or standard
IMP
1 reference
retrieved
21 June 2018
stated in
Agonist-directed trafficking of signalling at serotonin 5-HT2A, 5-HT2B and 5-HT2C-VSV receptors mediated Gq/11 activation and calcium mobilisation in CHO cells
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P28335&geneProductId=UniProtKB:P28335
determination method or standard
IMP
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
determination method or standard
ISS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
ISS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IEA
phospholipase C-activating serotonin receptor signaling pathway
determination method or standard
ISS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
ISS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IEA
locomotory behavior
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IEA
positive regulation of phosphatidylinositol biosynthetic process
determination method or standard
IDA
1 reference
retrieved
8 April 2019
stated in
Pharmacological characterization of mitogen-activated protein kinase activation by recombinant human 5-HT2C, 5-HT2A, and 5-HT2B receptors
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IDA
cellular calcium ion homeostasis
determination method or standard
IDA
1 reference
retrieved
8 April 2019
stated in
Pharmacological characterization of mitogen-activated protein kinase activation by recombinant human 5-HT2C, 5-HT2A, and 5-HT2B receptors
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IDA
behavioral fear response
determination method or standard
ISS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
ISS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IEA
regulation of nervous system process
determination method or standard
ISS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
ISS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IEA
cGMP biosynthetic process
determination method or standard
IDA
1 reference
retrieved
1 January 2018
stated in
Agonist actions of dihydroergotamine at 5-HT2B and 5-HT2C receptors and their possible relevance to antimigraine efficacy
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P28335&geneProductId=UniProtKB:P28335
determination method or standard
IDA
phospholipase C-activating G protein-coupled receptor signaling pathway
determination method or standard
IDA
1 reference
retrieved
21 June 2018
stated in
Agonist actions of dihydroergotamine at 5-HT2B and 5-HT2C receptors and their possible relevance to antimigraine efficacy
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P28335&geneProductId=UniProtKB:P28335
determination method or standard
IDA
serotonin receptor signaling pathway
determination method or standard
IMP
1 reference
retrieved
8 April 2019
stated in
Agonist-directed trafficking of signalling at serotonin 5-HT2A, 5-HT2B and 5-HT2C-VSV receptors mediated Gq/11 activation and calcium mobilisation in CHO cells
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IMP
feeding behavior
determination method or standard
ISS
IEA
TAS
4 references
retrieved
8 April 2019
stated in
Eating disorder and epilepsy in mice lacking 5-HT2c serotonin receptors
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
ISS
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IEA
positive regulation of ERK1 and ERK2 cascade
determination method or standard
IDA
1 reference
retrieved
8 April 2019
stated in
Pharmacological characterization of mitogen-activated protein kinase activation by recombinant human 5-HT2C, 5-HT2A, and 5-HT2B receptors
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IDA
regulation of corticotropin-releasing hormone secretion
determination method or standard
ISS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
ISS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IEA
regulation of appetite
determination method or standard
ISS
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
ISS
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IEA
positive regulation of fat cell differentiation
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IEA
signal transduction
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IEA
chemical synaptic transmission
determination method or standard
TAS
1 reference
retrieved
21 June 2018
stated in
Sound-induced seizures in serotonin 5-HT2c receptor mutant mice
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P28335&geneProductId=UniProtKB:P28335
determination method or standard
TAS
G protein-coupled receptor signaling pathway
determination method or standard
IEA
TAS
3 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IEA
animal behavior
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IEA
cGMP-mediated signaling
determination method or standard
IDA
1 reference
retrieved
8 April 2019
stated in
Agonist actions of dihydroergotamine at 5-HT2B and 5-HT2C receptors and their possible relevance to antimigraine efficacy
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IDA
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
determination method or standard
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IBA
phospholipase C-activating G protein-coupled receptor signaling pathway
determination method or standard
IBA
IDA
2 references
retrieved
8 April 2019
stated in
Agonist actions of dihydroergotamine at 5-HT2B and 5-HT2C receptors and their possible relevance to antimigraine efficacy
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IBA
chemical synaptic transmission
determination method or standard
IBA
TAS
2 references
retrieved
8 April 2019
stated in
Sound-induced seizures in serotonin 5-HT2c receptor mutant mice
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
TAS
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IBA
release of sequestered calcium ion into cytosol
determination method or standard
IBA
IMP
2 references
retrieved
8 April 2019
stated in
Agonist-directed trafficking of signalling at serotonin 5-HT2A, 5-HT2B and 5-HT2C-VSV receptors mediated Gq/11 activation and calcium mobilisation in CHO cells
GOA
curator
UniProt
UniProt protein ID
P28335
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IMP
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28335
determination method or standard
IBA
physically interacts with
lorcaserin
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
2941
language of work or name
English
retrieved
17 August 2016
5-carboxamidotryptamine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
4
language of work or name
English
retrieved
17 August 2016
serotonin
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
5
language of work or name
English
retrieved
17 August 2016
N,N-dimethyl-5-methoxytryptamine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
145
language of work or name
English
retrieved
17 August 2016
5-methoxytryptamine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
107
language of work or name
English
retrieved
17 August 2016
(+/-)-8-hydroxy-2-(di-N-propylamino)tetralin
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
7
language of work or name
English
retrieved
17 August 2016
AL-37350A
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
160
language of work or name
English
retrieved
17 August 2016
α-methyl-5-HT
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
152
language of work or name
English
retrieved
17 August 2016
aripiprazole
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
34
language of work or name
English
retrieved
17 August 2016
(RS)-brolamfetamine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
163
language of work or name
English
retrieved
17 August 2016
BW723C86
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
161
language of work or name
English
retrieved
17 August 2016
cabergoline
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
37
language of work or name
English
retrieved
17 August 2016
CGS-12066A
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
109
language of work or name
English
retrieved
17 August 2016
4-iodo-2,5-dimethoxyphenylisopropylamine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
147
language of work or name
English
retrieved
17 August 2016
lysergic acid diethylamide
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
17
language of work or name
English
retrieved
17 August 2016
methylergonovine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
150
language of work or name
English
retrieved
17 August 2016
MK-212
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
165
language of work or name
English
retrieved
17 August 2016
Org 12962
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
170
language of work or name
English
retrieved
17 August 2016
ORG-37684
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
171
language of work or name
English
retrieved
17 August 2016
oxymetazoline
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
124
language of work or name
English
retrieved
17 August 2016
quinpirole
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
2
language of work or name
English
retrieved
17 August 2016
quipazine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
173
language of work or name
English
retrieved
17 August 2016
ru-24969
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
23
language of work or name
English
retrieved
17 August 2016
1-(3-trifluoromethylphenyl)piperazine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
115
language of work or name
English
retrieved
17 August 2016
tryptamine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
125
language of work or name
English
retrieved
17 August 2016
VER-3323
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
168
language of work or name
English
retrieved
17 August 2016
YM348
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
230
language of work or name
English
retrieved
17 August 2016
brl-15572
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
10
language of work or name
English
retrieved
17 August 2016
bromocriptine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
35
language of work or name
English
retrieved
17 August 2016
ergotamine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
149
language of work or name
English
retrieved
17 August 2016
gr-127935
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
14
language of work or name
English
retrieved
17 August 2016
m-chlorophenylpiperazine
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
142
language of work or name
English
retrieved
17 August 2016
lisuride
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
43
language of work or name
English
retrieved
17 August 2016
pergolide
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
48
language of work or name
English
retrieved
17 August 2016
sb-216641
has use
agonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
28
language of work or name
English
retrieved
17 August 2016
agomelatine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
198
language of work or name
English
retrieved
17 August 2016
apomorphine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
33
language of work or name
English
retrieved
17 August 2016
chlorpromazine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
83
language of work or name
English
retrieved
17 August 2016
cyamemazine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
84
language of work or name
English
retrieved
17 August 2016
(S)-duloxetine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
202
language of work or name
English
retrieved
17 August 2016
glemanserin
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
186
language of work or name
English
retrieved
17 August 2016
ketanserin
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
88
language of work or name
English
retrieved
17 August 2016
mesoridazine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
7227
language of work or name
English
retrieved
17 August 2016
methysergide
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
134
language of work or name
English
retrieved
17 August 2016
mirtazapine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
7241
language of work or name
English
retrieved
17 August 2016
perphenazine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
209
language of work or name
English
retrieved
17 August 2016
ritanserin
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
97
language of work or name
English
retrieved
17 August 2016
roxindole
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
52
language of work or name
English
retrieved
17 August 2016
RS-102221
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
187
language of work or name
English
retrieved
17 August 2016
RS-127445
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
188
language of work or name
English
retrieved
17 August 2016
sarpogrelate
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
210
language of work or name
English
retrieved
17 August 2016
SB 204741
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
221
language of work or name
English
retrieved
17 August 2016
sb-206553
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
189
language of work or name
English
retrieved
17 August 2016
SB 242084
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
193
language of work or name
English
retrieved
17 August 2016
SB 243213
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
194
language of work or name
English
retrieved
17 August 2016
SDZ SER-082
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
195
language of work or name
English
retrieved
17 August 2016
spiperone
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
99
language of work or name
English
retrieved
17 August 2016
spiramide
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
175
language of work or name
English
retrieved
17 August 2016
terguride
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
56
language of work or name
English
retrieved
17 August 2016
thioridazine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
100
language of work or name
English
retrieved
17 August 2016
trazodone
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
213
language of work or name
English
retrieved
17 August 2016
trifluoperazine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
214
language of work or name
English
retrieved
17 August 2016
volinanserin
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
185
language of work or name
English
retrieved
17 August 2016
vortioxetine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
7351
language of work or name
English
retrieved
17 August 2016
xanomeline
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
57
language of work or name
English
retrieved
17 August 2016
clozapine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
38
language of work or name
English
retrieved
17 August 2016
loxapine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
205
language of work or name
English
retrieved
17 August 2016
mesulergine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
206
language of work or name
English
retrieved
17 August 2016
metergoline
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
133
language of work or name
English
retrieved
17 August 2016
metitepine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
89
language of work or name
English
retrieved
17 August 2016
(RS)-mianserin
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
135
language of work or name
English
retrieved
17 August 2016
olanzapine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
47
language of work or name
English
retrieved
17 August 2016
risperidone
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
96
language of work or name
English
retrieved
17 August 2016
sertindole
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
98
language of work or name
English
retrieved
17 August 2016
tiospirone
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
101
language of work or name
English
retrieved
17 August 2016
ziprasidone
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
59
language of work or name
English
retrieved
17 August 2016
zotepine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
103
language of work or name
English
retrieved
17 August 2016
idalopirdine
has use
antagonist
1 reference
stated in
IUPHAR/BPS Guide to PHARMACOLOGY
Guide to Pharmacology Ligand ID
8689
language of work or name
English
retrieved
17 August 2016
has part(s)
GPCR, rhodopsin-like, 7TM
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P28335
Identifiers
RefSeq protein ID
NP_000859
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
3358
NP_001243689
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
3358
NP_001243690
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
3358
UniProt protein ID
P28335
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
P28335
Ensembl protein ID
ENSP00000276198
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000276198
ENSP00000361018
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000361018
ENSP00000361019
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000361019
Sitelinks
Wikipedia
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Wikibooks
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(0 entries)
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Wikiquote
(0 entries)
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Wikisource
(0 entries)
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Wikiversity
(0 entries)
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Wikivoyage
(0 entries)
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Wiktionary
(0 entries)
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Multilingual sites
(0 entries)
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Retrieved from "
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5-hydroxytryptamine receptor 2C
(Q21108118)
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