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Nuclear receptor subfamily 0, group B, member 1
(Q15314643)
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From Wikidata
mammalian protein found in Mus musculus
nuclear receptor subfamily 0 group B member 1
adrenal hypoplasia congenita-like protein
nuclear receptor DAX-1
adrenal hypoplasia, congenital homolog
Nr0b1
edit
Language
Label
Description
Also known as
default for all languages
No label defined
–
English
Nuclear receptor subfamily 0, group B, member 1
mammalian protein found in Mus musculus
nuclear receptor subfamily 0 group B member 1
adrenal hypoplasia congenita-like protein
nuclear receptor DAX-1
adrenal hypoplasia, congenital homolog
Nr0b1
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q61066
part of
Nuclear hormone receptor-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q61066
Nuclear receptor subfamily 0 group B member 1
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q61066
membrane protein
1 reference
based on heuristic
inferred from GOA cell component → membrane
Nuclear hormone receptor, ligand-binding domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Nuclear receptor repeat, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
house mouse
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q61066
encoded by
Nr0b1
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q61066
molecular function
DNA binding
determination method or standard
IEA
ISO
3 references
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
ISO
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IEA
protein homodimerization activity
determination method or standard
IEA
ISO
2 references
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
ISO
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IEA
transcription corepressor activity
determination method or standard
IGI
IEA
ISO
3 references
retrieved
24 April 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61066&geneProductId=UniProtKB:Q61066
determination method or standard
ISO
retrieved
24 April 2018
stated in
The atypical orphan nuclear receptor DAX-1 interacts with orphan nuclear receptor Nur77 and represses its transactivation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61066&geneProductId=UniProtKB:Q61066
determination method or standard
IGI
retrieved
24 April 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61066&geneProductId=UniProtKB:Q61066
determination method or standard
IEA
protein domain specific binding
determination method or standard
IEA
ISO
2 references
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
ISO
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IEA
DNA hairpin binding
determination method or standard
IEA
ISO
2 references
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
ISO
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IEA
steroid hormone receptor activity
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IEA
nuclear receptor activity
determination method or standard
IEA
ISO
2 references
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
ISO
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IEA
protein binding
determination method or standard
IPI
7 references
retrieved
8 April 2019
stated in
Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells
GOA
curator
UniProt
UniProt protein ID
Q61066
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IPI
retrieved
8 April 2019
stated in
Dax1 associates with Esrrb and regulates its function in embryonic stem cells
GOA
curator
UniProt
UniProt protein ID
Q61066
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IPI
retrieved
8 April 2019
stated in
Esrrb directly binds to Gata6 promoter and regulates its expression with Dax1 and Ncoa3
GOA
curator
UniProt
UniProt protein ID
Q61066
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IPI
retrieved
8 April 2019
stated in
The atypical orphan nuclear receptor DAX-1 interacts with orphan nuclear receptor Nur77 and represses its transactivation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IPI
retrieved
8 April 2019
stated in
A protein interaction network for pluripotency of embryonic stem cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IPI
retrieved
8 April 2019
stated in
An Oct4-centered protein interaction network in embryonic stem cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IPI
retrieved
8 April 2019
stated in
A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IPI
RNA binding
determination method or standard
IDA
IEA
ISO
3 references
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
ISO
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IEA
retrieved
8 April 2019
stated in
Orphan receptor DAX-1 is a shuttling RNA binding protein associated with polyribosomes via mRNA
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IDA
AF-2 domain binding
determination method or standard
ISO
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
ISO
transcription factor binding
determination method or standard
IEA
IPI
ISO
4 references
retrieved
24 April 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61066&geneProductId=UniProtKB:Q61066
determination method or standard
ISO
retrieved
24 April 2018
stated in
Esrrb directly binds to Gata6 promoter and regulates its expression with Dax1 and Ncoa3
GOA
curator
UniProt
UniProt protein ID
Q61066
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61066&geneProductId=UniProtKB:Q61066
determination method or standard
IPI
retrieved
24 April 2018
stated in
Dax1 associates with Esrrb and regulates its function in embryonic stem cells
GOA
curator
UniProt
UniProt protein ID
Q61066
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61066&geneProductId=UniProtKB:Q61066
determination method or standard
IPI
retrieved
24 April 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61066&geneProductId=UniProtKB:Q61066
determination method or standard
IEA
sequence-specific DNA binding
determination method or standard
IDA
1 reference
retrieved
24 April 2018
stated in
Esrrb directly binds to Gata6 promoter and regulates its expression with Dax1 and Ncoa3
GOA
curator
UniProt
UniProt protein ID
Q61066
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61066&geneProductId=UniProtKB:Q61066
determination method or standard
IDA
double-stranded DNA binding
determination method or standard
ISO
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
ISO
transcription corepressor activity
determination method or standard
IBA
IEA
IGI
ISO
4 references
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
ISO
retrieved
8 April 2019
stated in
The atypical orphan nuclear receptor DAX-1 interacts with orphan nuclear receptor Nur77 and represses its transactivation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IGI
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IBA
transcription factor binding
determination method or standard
IBA
IEA
IPI
ISO
5 references
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
ISO
retrieved
8 April 2019
stated in
Dax1 associates with Esrrb and regulates its function in embryonic stem cells
GOA
curator
UniProt
UniProt protein ID
Q61066
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IPI
retrieved
8 April 2019
stated in
Esrrb directly binds to Gata6 promoter and regulates its expression with Dax1 and Ncoa3
GOA
curator
UniProt
UniProt protein ID
Q61066
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IPI
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IBA
sequence-specific DNA binding
determination method or standard
IBA
IDA
2 references
retrieved
8 April 2019
stated in
Esrrb directly binds to Gata6 promoter and regulates its expression with Dax1 and Ncoa3
GOA
curator
UniProt
UniProt protein ID
Q61066
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IBA
cell component
cytoplasm
determination method or standard
IDA
IEA
ISO
6 references
retrieved
24 April 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61066&geneProductId=UniProtKB:Q61066
determination method or standard
ISO
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q61066
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61066&geneProductId=UniProtKB:Q61066
determination method or standard
IEA
retrieved
24 April 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61066&geneProductId=UniProtKB:Q61066
determination method or standard
IEA
retrieved
24 April 2018
stated in
Role of the LXXLL-motif and activation function 2 domain in subcellular localization of Dax-1 (dosage-sensitive sex reversal-adrenal hypoplasia congenita critical region on the X chromosome, gene 1)
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61066&geneProductId=UniProtKB:Q61066
determination method or standard
IDA
retrieved
24 April 2018
stated in
Novel role for the orphan nuclear receptor Dax1 in embryogenesis, different from steroidogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61066&geneProductId=UniProtKB:Q61066
determination method or standard
IDA
retrieved
24 April 2018
stated in
Nr0b1 and its network partners are expressed early in murine embryos prior to steroidogenic axis organogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61066&geneProductId=UniProtKB:Q61066
determination method or standard
IDA
membrane
determination method or standard
IEA
ISO
2 references
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
ISO
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IEA
nucleus
determination method or standard
IDA
IEA
ISO
6 references
retrieved
24 April 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61066&geneProductId=UniProtKB:Q61066
determination method or standard
ISO
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q61066
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61066&geneProductId=UniProtKB:Q61066
determination method or standard
IEA
retrieved
24 April 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61066&geneProductId=UniProtKB:Q61066
determination method or standard
IEA
retrieved
24 April 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61066&geneProductId=UniProtKB:Q61066
determination method or standard
IEA
retrieved
24 April 2018
stated in
Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61066&geneProductId=UniProtKB:Q61066
determination method or standard
IDA
retrieved
24 April 2018
stated in
Orphan receptor DAX-1 is a shuttling RNA binding protein associated with polyribosomes via mRNA
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61066&geneProductId=UniProtKB:Q61066
determination method or standard
IDA
polysomal ribosome
determination method or standard
IDA
IEA
ISO
3 references
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
ISO
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IEA
retrieved
8 April 2019
stated in
Orphan receptor DAX-1 is a shuttling RNA binding protein associated with polyribosomes via mRNA
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IDA
microtubule organizing center
determination method or standard
IEA
ISO
2 references
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
ISO
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IEA
nuclear speck
determination method or standard
IEA
ISO
2 references
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
ISO
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IEA
intracellular membrane-bounded organelle
determination method or standard
IEA
ISO
2 references
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
ISO
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IEA
nucleus
determination method or standard
IBA
IDA
IEA
ISO
7 references
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
ISO
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q61066
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IEA
retrieved
8 April 2019
stated in
Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IDA
retrieved
8 April 2019
stated in
Orphan receptor DAX-1 is a shuttling RNA binding protein associated with polyribosomes via mRNA
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IBA
cytoplasm
determination method or standard
IBA
IDA
IEA
ISO
7 references
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
ISO
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q61066
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IEA
retrieved
8 April 2019
stated in
Nr0b1 and its network partners are expressed early in murine embryos prior to steroidogenic axis organogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IDA
retrieved
8 April 2019
stated in
Role of the LXXLL-motif and activation function 2 domain in subcellular localization of Dax-1 (dosage-sensitive sex reversal-adrenal hypoplasia congenita critical region on the X chromosome, gene 1)
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IDA
retrieved
8 April 2019
stated in
Novel role for the orphan nuclear receptor Dax1 in embryogenesis, different from steroidogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IBA
biological process
response to immobilization stress
determination method or standard
IMP
1 reference
retrieved
8 April 2019
stated in
Interaction between Dax-1 and steroidogenic factor-1 in vivo: increased adrenal responsiveness to ACTH in the absence of Dax-1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IMP
protein localization
determination method or standard
IEA
ISO
2 references
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
ISO
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IEA
cell differentiation
determination method or standard
IGI
1 reference
retrieved
14 February 2019
stated in
Nuclear receptors Sf1 and Dax1 function cooperatively to mediate somatic cell differentiation during testis development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IGI
male gonad development
determination method or standard
IEA
IMP
ISO
3 references
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
ISO
retrieved
8 April 2019
stated in
Dax1 is required for testis determination
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IMP
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IEA
negative regulation of intracellular steroid hormone receptor signaling pathway
determination method or standard
IEA
ISO
2 references
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
ISO
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IEA
regulation of transcription, DNA-templated
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IEA
Leydig cell differentiation
determination method or standard
IMP
1 reference
retrieved
8 April 2019
stated in
Blockage of the rete testis and efferent ductules by ectopic Sertoli and Leydig cells causes infertility in Dax1-deficient male mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IMP
negative regulation of cell differentiation
determination method or standard
IMP
1 reference
retrieved
14 February 2019
stated in
Novel role for the orphan nuclear receptor Dax1 in embryogenesis, different from steroidogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IMP
Sertoli cell differentiation
determination method or standard
IMP
1 reference
retrieved
8 April 2019
stated in
Blockage of the rete testis and efferent ductules by ectopic Sertoli and Leydig cells causes infertility in Dax1-deficient male mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IMP
adrenal gland development
determination method or standard
IGI
IEA
ISO
4 references
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
ISO
retrieved
8 April 2019
stated in
Interaction between Dax-1 and steroidogenic factor-1 in vivo: increased adrenal responsiveness to ACTH in the absence of Dax-1
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IGI
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IEA
male sex determination
determination method or standard
IGI
IMP
3 references
retrieved
8 April 2019
stated in
Dax1 is required for testis determination
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IMP
retrieved
8 April 2019
stated in
Gonadal sex reversal in mutant Dax1 XY mice: a failure to upregulate Sox9 in pre-Sertoli cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IMP
retrieved
8 April 2019
stated in
Gonadal sex reversal in mutant Dax1 XY mice: a failure to upregulate Sox9 in pre-Sertoli cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IGI
transcription, DNA-templated
determination method or standard
IEA
1 reference
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q61066
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61066&geneProductId=UniProtKB:Q61066
determination method or standard
IEA
sex-determination system
determination method or standard
IGI
1 reference
retrieved
8 April 2019
stated in
Dax1 antagonizes Sry action in mammalian sex determination
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IGI
spermatogenesis
determination method or standard
IMP
2 references
retrieved
8 April 2019
stated in
Sertoli cell-specific rescue of fertility, but not testicular pathology, in Dax1 (Ahch)-deficient male mice
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IMP
retrieved
8 April 2019
stated in
Role of Ahch in gonadal development and gametogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IMP
negative regulation of transcription, DNA-templated
determination method or standard
IDA
IEA
ISO
5 references
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
ISO
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IEA
retrieved
8 April 2019
stated in
Dax1 associates with Esrrb and regulates its function in embryonic stem cells
GOA
curator
UniProt
UniProt protein ID
Q61066
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IDA
retrieved
8 April 2019
stated in
Esrrb directly binds to Gata6 promoter and regulates its expression with Dax1 and Ncoa3
GOA
curator
UniProt
UniProt protein ID
Q61066
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IDA
retrieved
8 April 2019
stated in
Mixed lineage kinase 2 enhances trans-repression of Alien and nuclear receptors
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IDA
gonad development
determination method or standard
IEA
ISO
2 references
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
ISO
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IEA
steroid hormone mediated signaling pathway
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IEA
steroid biosynthetic process
determination method or standard
IEA
ISO
2 references
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
ISO
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IEA
intracellular receptor signaling pathway
determination method or standard
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IEA
negative regulation of DNA-binding transcription factor activity
determination method or standard
IEA
ISO
2 references
retrieved
24 April 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61066&geneProductId=UniProtKB:Q61066
determination method or standard
ISO
retrieved
24 April 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61066&geneProductId=UniProtKB:Q61066
determination method or standard
IEA
negative regulation of transcription by RNA polymerase II
determination method or standard
IGI
IMP
ISO
3 references
retrieved
24 April 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61066&geneProductId=UniProtKB:Q61066
determination method or standard
ISO
retrieved
24 April 2018
stated in
The atypical orphan nuclear receptor DAX-1 interacts with orphan nuclear receptor Nur77 and represses its transactivation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61066&geneProductId=UniProtKB:Q61066
determination method or standard
IMP
retrieved
24 April 2018
stated in
The atypical orphan nuclear receptor DAX-1 interacts with orphan nuclear receptor Nur77 and represses its transactivation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61066&geneProductId=UniProtKB:Q61066
determination method or standard
IGI
negative regulation of transcription by RNA polymerase II
determination method or standard
IBA
IGI
IMP
ISO
4 references
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
ISO
retrieved
8 April 2019
stated in
The atypical orphan nuclear receptor DAX-1 interacts with orphan nuclear receptor Nur77 and represses its transactivation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IMP
retrieved
8 April 2019
stated in
The atypical orphan nuclear receptor DAX-1 interacts with orphan nuclear receptor Nur77 and represses its transactivation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IGI
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IBA
negative regulation of DNA-binding transcription factor activity
determination method or standard
IBA
IEA
ISO
3 references
retrieved
8 April 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
ISO
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IBA
cell differentiation
determination method or standard
IGI
IMP
2 references
retrieved
8 April 2019
stated in
Novel role for the orphan nuclear receptor Dax1 in embryogenesis, different from steroidogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IMP
retrieved
8 April 2019
stated in
Nuclear receptors Sf1 and Dax1 function cooperatively to mediate somatic cell differentiation during testis development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61066
determination method or standard
IGI
has part(s)
Nuclear receptor repeat
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q61066
Nuclear hormone receptor, ligand-binding domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q61066
Identifiers
RefSeq protein ID
NP_031456
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
11614
UniProt protein ID
Q61066
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q61066
Ensembl protein ID
ENSMUSP00000026036
1 reference
stated in
ensembl Release 106
Ensembl protein ID
ENSMUSP00000026036
PDB structure ID
3F5C
1 reference
stated in
UniProt
UniProt protein ID
Q61066
retrieved
9 August 2016
language of work or name
English
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Nuclear receptor subfamily 0, group B, member 1
(Q15314643)
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