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APOB
(Q14890615)
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From Wikidata
protein-coding gene in the species Homo sapiens
FLDB
LDLCQ4
apoB-100
apoB-48
apolipoprotein B
FCHL2
edit
Language
Label
Description
Also known as
default for all languages
No label defined
–
English
APOB
protein-coding gene in the species Homo sapiens
FLDB
LDLCQ4
apoB-100
apoB-48
apolipoprotein B
FCHL2
Statements
instance of
gene
1 reference
stated in
ensembl Release 106
Ensembl gene ID
ENSG00000084674
subclass of
protein-coding gene
1 reference
stated in
Ensembl Release 87
Ensembl gene ID
ENSG00000084674
found in taxon
Homo sapiens
1 reference
stated in
ensembl Release 106
Ensembl gene ID
ENSG00000084674
encodes
Apolipoprotein B
1 reference
stated in
UniProt
retrieved
16 March 2017
UniProt protein ID
P04114
genetic association
metabolic disease
determination method or standard
genome-wide association study
TAS
1 reference
reference URL
https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_0014667&ncbiId=338
http://www.genome.gov/gwastudies/index.cfm?gene=APOB
stated in
Phenocarta
Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits
retrieved
25 May 2020
cardiovascular disease
determination method or standard
genome-wide association study
TAS
1 reference
reference URL
https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_1287&ncbiId=338
http://www.genome.gov/gwastudies/index.cfm?gene=APOB
stated in
Phenocarta
Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits
retrieved
25 May 2020
lipid metabolism disorder
determination method or standard
genome-wide association study
TAS
1 reference
reference URL
https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_3146&ncbiId=338
http://www.genome.gov/gwastudies/index.cfm?gene=APOB
stated in
Phenocarta
Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis
retrieved
25 May 2020
familial hypobetalipoproteinemia 1
5 references
stated in
UniProt
UniProt protein ID
P04114
retrieved
13 August 2019
stated in
ClinGen
retrieved
28 December 2020
reference URL
https://search.clinicalgenome.org/kb/gene-validity/--2020-02-26T17:00:00
stated in
ClinGen
retrieved
11 January 2021
reference URL
https://search.clinicalgenome.org/kb/gene-validity/e7382aae-83d5-4a23-b1fe-e3d6acea8584--2020-02-26T17:00:00
stated in
ClinGen
retrieved
25 January 2022
reference URL
https://search.clinicalgenome.org/kb/gene-validity/CGGV:assertion_e7382aae-83d5-4a23-b1fe-e3d6acea8584-2020-02-26T170000.000Z
stated in
Open Targets Platform
retrieved
24 August 2023
reference URL
https://platform.opentargets.org/evidence/ENSG00000084674/MONDO_0014252
based on heuristic
inferred from an Open Targets association score over 0.7
hypercholesterolemia, autosomal dominant, type b
4 references
stated in
ClinGen
retrieved
4 May 2020
reference URL
https://search.clinicalgenome.org/kb/gene-validity/1c26b83b-409e-47c7-9c53-6ca79472d6fc--2018-11-14T17:00:00
stated in
ClinGen
retrieved
28 December 2020
reference URL
https://search.clinicalgenome.org/kb/gene-validity/1c26b83b-409e-47c7-9c53-6ca79472d6fc--2018-11-14T18:00:00
stated in
ClinGen
retrieved
25 January 2022
reference URL
https://search.clinicalgenome.org/kb/gene-validity/CGGV:assertion_1c26b83b-409e-47c7-9c53-6ca79472d6fc-2018-11-14T180000.000Z
stated in
Open Targets Platform
retrieved
24 August 2023
reference URL
https://platform.opentargets.org/evidence/ENSG00000084674/MONDO_0007751
based on heuristic
inferred from an Open Targets association score over 0.7
hypercholesterolemia, familial, 2
0 references
familial hypercholesterolemia
1 reference
stated in
Open Targets Platform
retrieved
24 August 2023
reference URL
https://platform.opentargets.org/evidence/ENSG00000084674/EFO_0004911
based on heuristic
inferred from an Open Targets association score over 0.7
hypobetalipoproteinemia
1 reference
stated in
Open Targets Platform
retrieved
24 August 2023
reference URL
https://platform.opentargets.org/evidence/ENSG00000084674/MONDO_0017774
based on heuristic
inferred from an Open Targets association score over 0.7
chromosome
human chromosome 2
genomic assembly
genome assembly GRCh38
Genome assembly GRCh37
1 reference
stated in
ensembl Release 106
Ensembl gene ID
ENSG00000084674
strand orientation
reverse strand
genomic assembly
genome assembly GRCh38
Genome assembly GRCh37
1 reference
stated in
ensembl Release 106
Ensembl gene ID
ENSG00000084674
genomic start
21001429
chromosome
human chromosome 2
genomic assembly
genome assembly GRCh38
1 reference
stated in
ensembl Release 106
Ensembl gene ID
ENSG00000084674
21224301
chromosome
human chromosome 2
genomic assembly
Genome assembly GRCh37
1 reference
stated in
ensembl Release 106
Ensembl gene ID
ENSG00000084674
genomic end
21044073
chromosome
human chromosome 2
genomic assembly
genome assembly GRCh38
1 reference
stated in
ensembl Release 106
Ensembl gene ID
ENSG00000084674
21266945
chromosome
human chromosome 2
genomic assembly
Genome assembly GRCh37
1 reference
stated in
ensembl Release 106
Ensembl gene ID
ENSG00000084674
cytogenetic location
2p24.1
1 reference
stated in
NCBI Gene
retrieved
15 May 2022
Entrez Gene ID
338
molecular function
lipid transporter activity
determination method or standard
IEA
1 reference
retrieved
18 July 2017
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
protein binding
determination method or standard
IPI
8 references
retrieved
18 July 2017
stated in
Novel missense MTTP gene mutations causing abetalipoproteinemia
GOA
curator
UniProt
UniProt protein ID
P04114
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IPI
retrieved
18 July 2017
stated in
Novel Abetalipoproteinemia Missense Mutation Highlights the Importance of the N-Terminal β-Barrel in Microsomal Triglyceride Transfer Protein Function
GOA
curator
UniProt
UniProt protein ID
P04114
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IPI
retrieved
18 July 2017
stated in
TANGO1 and Mia2/cTAGE5 (TALI) cooperate to export bulky pre-chylomicrons/VLDLs from the endoplasmic reticulum
GOA
curator
UniProt
UniProt protein ID
P04114
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IPI
retrieved
18 July 2017
stated in
Proprotein convertase subtilisin/kexin type 9 interacts with apolipoprotein B and prevents its intracellular degradation, irrespective of the low-density lipoprotein receptor
GOA
curator
UniProt
UniProt protein ID
P04114
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IPI
retrieved
18 July 2017
stated in
LDL receptor/lipoprotein recognition: endosomal weakening of ApoB and ApoE binding to the convex face of the LR5 repeat
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IPI
retrieved
18 July 2017
stated in
A physical interaction network of dengue virus and human proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IPI
retrieved
18 July 2017
stated in
Identification of disulfide-linked apolipoprotein species in human lipoproteins
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IPI
retrieved
18 July 2017
stated in
Hepatitis C virus nonstructural proteins inhibit apolipoprotein B100 secretion
GOA
curator
AgBase
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IPI
phospholipid binding
determination method or standard
IDA
1 reference
retrieved
18 July 2017
stated in
Sulfhydryl chemistry and solubility properties of human plasma apolipoprotein B
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IDA
heparin binding
determination method or standard
IDA
IEA
2 references
retrieved
18 July 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P04114
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
retrieved
18 July 2017
stated in
The effect of heparin on structural and functional properties of low density lipoproteins
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IDA
lipid binding
determination method or standard
IEA
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
cholesterol transfer activity
determination method or standard
IMP
1 reference
retrieved
18 July 2017
stated in
Mutation in apolipoprotein B associated with hypobetalipoproteinemia despite decreased binding to the low density lipoprotein receptor
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IMP
lipase binding
determination method or standard
IPI
1 reference
retrieved
18 July 2017
stated in
Interaction between ApoB and Hepatic Lipase Mediates the Uptake of ApoB-containing Lipoproteins
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IPI
low-density lipoprotein particle receptor binding
determination method or standard
IMP
2 references
retrieved
18 July 2017
stated in
Association between a specific apolipoprotein B mutation and familial defective apolipoprotein B-100
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IMP
retrieved
18 July 2017
stated in
Mutation in apolipoprotein B associated with hypobetalipoproteinemia despite decreased binding to the low density lipoprotein receptor
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IMP
cell component
extracellular region
determination method or standard
IEA
TAS
2 references
retrieved
18 July 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
TAS
retrieved
18 July 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P04114
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
extracellular space
determination method or standard
IEA
ISS
2 references
retrieved
18 July 2017
stated in
Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
ISS
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
cytoplasm
determination method or standard
IDA
IEA
2 references
retrieved
18 July 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P04114
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
retrieved
18 July 2017
stated in
Proprotein convertase subtilisin/kexin type 9 interacts with apolipoprotein B and prevents its intracellular degradation, irrespective of the low-density lipoprotein receptor
GOA
curator
UniProt
UniProt protein ID
P04114
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IDA
early endosome
determination method or standard
TAS
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
TAS
endoplasmic reticulum
determination method or standard
IEA
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
endoplasmic reticulum lumen
determination method or standard
TAS
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
TAS
endoplasmic reticulum membrane
determination method or standard
TAS
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
TAS
smooth endoplasmic reticulum
determination method or standard
TAS
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
TAS
cytosol
determination method or standard
IDA
TAS
2 references
retrieved
18 July 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
TAS
retrieved
18 July 2017
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IDA
plasma membrane
determination method or standard
TAS
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
TAS
endosome membrane
determination method or standard
TAS
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
TAS
vesicle membrane
determination method or standard
IEA
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
clathrin-coated endocytic vesicle membrane
determination method or standard
TAS
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
TAS
endosome lumen
determination method or standard
TAS
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
TAS
vesicle lumen
determination method or standard
IEA
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
mature chylomicron
determination method or standard
IDA
1 reference
retrieved
18 July 2017
stated in
Assay of total plasma apolipoprotein B concentration in human subjects
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IDA
chylomicron remnant
determination method or standard
TAS
1 reference
retrieved
18 July 2017
stated in
Plasma lipoproteins: apolipoprotein structure and function
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
TAS
very-low-density lipoprotein particle
determination method or standard
IDA
IEA
4 references
retrieved
18 July 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P04114
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
retrieved
18 July 2017
stated in
Assay of total plasma apolipoprotein B concentration in human subjects
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IDA
retrieved
18 July 2017
stated in
Overexpression of human diacylglycerol acyltransferase 1, acyl-coa:cholesterol acyltransferase 1, or acyl-CoA:cholesterol acyltransferase 2 stimulates secretion of apolipoprotein B-containing lipoproteins in McA-RH7777 cells
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IDA
low-density lipoprotein particle
determination method or standard
IDA
IEA
3 references
retrieved
18 July 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P04114
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
retrieved
18 July 2017
stated in
Assay of total plasma apolipoprotein B concentration in human subjects
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IDA
intermediate-density lipoprotein particle
determination method or standard
IDA
1 reference
retrieved
18 July 2017
stated in
Mechanisms of inhibition by apolipoprotein C of apolipoprotein E-dependent cellular metabolism of human triglyceride-rich lipoproteins through the low density lipoprotein receptor pathway
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IDA
chylomicron
determination method or standard
IDA
IEA
3 references
retrieved
18 July 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P04114
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
retrieved
18 July 2017
stated in
Assay of total plasma apolipoprotein B concentration in human subjects
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IDA
retrieved
18 July 2017
stated in
Identification of disulfide-linked apolipoprotein species in human lipoproteins
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IDA
soma
determination method or standard
IDA
1 reference
retrieved
18 July 2017
stated in
Apolipoprotein B is a new target of the GDNF/RET and ET-3/EDNRB signalling pathways
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IDA
lysosomal lumen
determination method or standard
TAS
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
TAS
intracellular membrane-bounded organelle
determination method or standard
IDA
IEA
TAS
3 references
retrieved
18 July 2017
stated in
Apolipoprotein B
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
TAS
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
retrieved
18 July 2017
stated in
GOA
curator
Human Protein Atlas
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IDA
extracellular exosome
determination method or standard
IDA
1 reference
retrieved
18 July 2017
stated in
In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine
GOA
curator
UniProt
UniProt protein ID
P04114
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IDA
endoplasmic reticulum exit site
determination method or standard
IDA
1 reference
retrieved
18 July 2017
stated in
TANGO1 and Mia2/cTAGE5 (TALI) cooperate to export bulky pre-chylomicrons/VLDLs from the endoplasmic reticulum
GOA
curator
UniProt
UniProt protein ID
P04114
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IDA
endocytic vesicle lumen
determination method or standard
TAS
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
TAS
biological process
retinoid metabolic process
determination method or standard
TAS
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
TAS
in utero embryonic development
determination method or standard
IEA
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
toll-like receptor signaling pathway
determination method or standard
TAS
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
TAS
lipid metabolism
determination method or standard
IEA
2 references
retrieved
18 July 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P04114
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
triglyceride mobilization
determination method or standard
IEA
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
transport
determination method or standard
IEA
1 reference
retrieved
18 July 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P04114
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
lipid transport
determination method or standard
IEA
2 references
retrieved
18 July 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P04114
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
retrieved
18 July 2017
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
receptor-mediated endocytosis
determination method or standard
TAS
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
TAS
spermatogenesis
determination method or standard
IEA
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
nervous system development
determination method or standard
IEA
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
steroid metabolic process
determination method or standard
IEA
1 reference
retrieved
18 July 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P04114
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
cholesterol metabolic process
determination method or standard
IEA
IMP
2 references
retrieved
18 July 2017
stated in
Association between a specific apolipoprotein B mutation and familial defective apolipoprotein B-100
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IMP
retrieved
18 July 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P04114
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
fertilization
determination method or standard
IEA
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
response to virus
determination method or standard
IEP
1 reference
retrieved
18 July 2017
stated in
Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection
GOA
curator
UniProt
UniProt protein ID
P04114
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEP
response to carbohydrate
determination method or standard
IEA
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
post-embryonic development
determination method or standard
IEA
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
response to organic substance
determination method or standard
IEA
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
response to selenium ion
determination method or standard
IEA
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
positive regulation of gene expression
determination method or standard
IEA
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
positive regulation of macrophage derived foam cell differentiation
determination method or standard
IDA
3 references
retrieved
18 July 2017
stated in
Induction of dendritic cell-like phenotype in macrophages during foam cell formation
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IDA
retrieved
18 July 2017
stated in
C-reactive protein-bound enzymatically modified low-density lipoprotein does not transform macrophages into foam cells
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IDA
retrieved
18 July 2017
stated in
Chlamydia pneumoniae induces macrophage-derived foam cell formation via PPAR alpha and PPAR gamma-dependent pathways
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IDA
positive regulation of lipid storage
determination method or standard
IDA
1 reference
retrieved
18 July 2017
stated in
C-reactive protein-bound enzymatically modified low-density lipoprotein does not transform macrophages into foam cells
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IDA
positive regulation of cholesterol storage
determination method or standard
IDA
1 reference
retrieved
18 July 2017
stated in
Chlamydia pneumoniae induces macrophage-derived foam cell formation via PPAR alpha and PPAR gamma-dependent pathways
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IDA
lipid catabolic process
determination method or standard
IEA
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
triglyceride catabolic process
determination method or standard
IEA
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
cholesterol transport
determination method or standard
IEA
IMP
2 references
retrieved
18 July 2017
stated in
Association between a specific apolipoprotein B mutation and familial defective apolipoprotein B-100
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IMP
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
flagellated sperm motility
determination method or standard
IEA
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
response to estradiol
determination method or standard
IEA
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
response to lipopolysaccharide
determination method or standard
IEA
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
cholesterol efflux
determination method or standard
IEA
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
chylomicron remodeling
determination method or standard
TAS
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
TAS
low-density lipoprotein particle remodeling
determination method or standard
IMP
TAS
2 references
retrieved
18 July 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
TAS
retrieved
18 July 2017
stated in
Mutation in apolipoprotein B associated with hypobetalipoproteinemia despite decreased binding to the low density lipoprotein receptor
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IMP
chylomicron assembly
determination method or standard
TAS
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
TAS
very-low-density lipoprotein particle assembly
determination method or standard
IC
TAS
2 references
retrieved
18 July 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
TAS
retrieved
18 July 2017
stated in
Overexpression of human diacylglycerol acyltransferase 1, acyl-coa:cholesterol acyltransferase 1, or acyl-CoA:cholesterol acyltransferase 2 stimulates secretion of apolipoprotein B-containing lipoproteins in McA-RH7777 cells
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IC
chylomicron remnant clearance
determination method or standard
TAS
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
TAS
low-density lipoprotein particle clearance
determination method or standard
IMP
TAS
3 references
retrieved
18 July 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
TAS
retrieved
18 July 2017
stated in
Association between a specific apolipoprotein B mutation and familial defective apolipoprotein B-100
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IMP
retrieved
18 July 2017
stated in
Mutation in apolipoprotein B associated with hypobetalipoproteinemia despite decreased binding to the low density lipoprotein receptor
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IMP
very-low-density lipoprotein particle clearance
determination method or standard
TAS
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
TAS
lipoprotein metabolic process
determination method or standard
IEA
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
lipoprotein biosynthetic process
determination method or standard
IEA
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
lipoprotein catabolic process
determination method or standard
IEA
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
cholesterol homeostasis
determination method or standard
IEA
IMP
2 references
retrieved
18 July 2017
stated in
Association between a specific apolipoprotein B mutation and familial defective apolipoprotein B-100
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IMP
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
lipoprotein transport
determination method or standard
IEA
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
post-translational protein modification
determination method or standard
TAS
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
TAS
regulation of cholesterol biosynthetic process
determination method or standard
IEA
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
artery morphogenesis
determination method or standard
IEA
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
leukocyte migration
determination method or standard
TAS
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
TAS
membrane organization
determination method or standard
TAS
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
TAS
cellular response to tumor necrosis factor
determination method or standard
IEA
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
cellular response to prostaglandin stimulus
determination method or standard
IEA
1 reference
retrieved
18 July 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P04114
determination method or standard
IEA
HomoloGene ID
328
1 reference
stated in
NCBI Gene
retrieved
15 May 2022
Entrez Gene ID
338
Gene Atlas image
PBB GE APOB 205108 s at fs.png
732 × 530; 8 KB
0 references
ortholog
Apob
found in taxon
house mouse
2 references
stated in
HomoloGene build68
HomoloGene ID
328
stated in
Orthologous MAtrix
reference URL
https://omabrowser.org/oma/vps/P04114/
Apob
found in taxon
brown rat
2 references
stated in
HomoloGene build68
HomoloGene ID
328
stated in
Orthologous MAtrix
reference URL
https://omabrowser.org/oma/vps/P04114/
apoba
found in taxon
Danio rerio
1 reference
stated in
HomoloGene build68
HomoloGene ID
328
expressed in
jejunal mucosa
series ordinal
1
1 reference
stated in
Bgee
retrieved
7 June 2024
reference URL
https://www.bgee.org/gene/ENSG00000084674
liver
series ordinal
2
1 reference
stated in
Bgee
retrieved
7 June 2024
reference URL
https://www.bgee.org/gene/ENSG00000084674
mucosa of ileum
series ordinal
3
1 reference
stated in
Bgee
retrieved
7 June 2024
reference URL
https://www.bgee.org/gene/ENSG00000084674
right lobe of liver
series ordinal
4
1 reference
stated in
Bgee
retrieved
7 June 2024
reference URL
https://www.bgee.org/gene/ENSG00000084674
duodenum
series ordinal
5
1 reference
stated in
Bgee
retrieved
7 June 2024
reference URL
https://www.bgee.org/gene/ENSG00000084674
right ventricle
series ordinal
6
1 reference
stated in
Bgee
retrieved
7 June 2024
reference URL
https://www.bgee.org/gene/ENSG00000084674
right auricle of heart
series ordinal
7
1 reference
stated in
Bgee
retrieved
7 June 2024
reference URL
https://www.bgee.org/gene/ENSG00000084674
myocardium
series ordinal
8
1 reference
stated in
Bgee
retrieved
7 June 2024
reference URL
https://www.bgee.org/gene/ENSG00000084674
left ventricle
series ordinal
9
1 reference
stated in
Bgee
retrieved
7 June 2024
reference URL
https://www.bgee.org/gene/ENSG00000084674
cardiac muscle tissue of right atrium
series ordinal
10
1 reference
stated in
Bgee
retrieved
7 June 2024
reference URL
https://www.bgee.org/gene/ENSG00000084674
exact match
http://identifiers.org/ncbigene/338
1 reference
stated in
Identifiers.org
reference URL
http://www.ebi.ac.uk/miriam/main/collections/MIR:00000069
Commons category
Apolipoprotein B
0 references
Identifiers
RefSeq RNA ID
NM_000384
1 reference
stated in
NCBI Gene
retrieved
15 May 2022
Entrez Gene ID
338
Entrez Gene ID
338
1 reference
stated in
NCBI Gene
retrieved
15 May 2022
Entrez Gene ID
338
Ensembl gene ID
ENSG00000084674
1 reference
stated in
ensembl Release 106
Ensembl gene ID
ENSG00000084674
Ensembl transcript ID
ENST00000233242
1 reference
stated in
ensembl Release 106
Ensembl gene ID
ENSG00000084674
ENST00000399256
1 reference
stated in
ensembl Release 106
Ensembl gene ID
ENSG00000084674
ENST00000673739
1 reference
stated in
ensembl Release 106
Ensembl gene ID
ENSG00000084674
ENST00000673882
1 reference
stated in
ensembl Release 106
Ensembl gene ID
ENSG00000084674
Freebase ID
/m/0byvmf
0 references
HGNC gene symbol
APOB
1 reference
stated in
NCBI Gene
retrieved
15 May 2022
Entrez Gene ID
338
HGNC ID
603
1 reference
stated in
NCBI Gene
retrieved
15 May 2022
Entrez Gene ID
338
Microsoft Academic ID (discontinued)
62746215
0 references
2910608094
0 references
OMIM ID
107730
1 reference
stated in
Online Mendelian Inheritance in Man
retrieved
19 August 2019
OpenAlex ID
C62746215
1 reference
stated in
OpenAlex
retrieved
26 January 2022
reference URL
https://docs.openalex.org/download-snapshot/snapshot-data-format
archive URL
https://web.archive.org/web/20220125070108/https://docs.openalex.org/download-snapshot/snapshot-data-format
archive date
25 January 2022
UMLS CUI
C1412471
1 reference
based on heuristic
inferred by common HGNC mappings on source and on Wikidata
stated in
UMLS 2023
retrieved
15 June 2023
Sitelinks
Wikipedia
(14 entries)
edit
arwiki
صميم البروتين الشحمي بي
arzwiki
صميم البروتين الشحمى بى
cawiki
Apolipoproteïna B
enwiki
Apolipoprotein B
eswiki
Apolipoproteína B
fawiki
آپولیپوپروتئین ب
fiwiki
Apolipoproteiini B
frwiki
Apolipoprotéine B
glwiki
Apolipoproteína B
hrwiki
Apolipoprotein B
ptwiki
Apolipoproteína B
ruwiki
Аполипопротеин B
ukwiki
Аполіпопротеїн B
zhwiki
载脂蛋白B
Wikibooks
(0 entries)
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Wikinews
(0 entries)
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Wikiquote
(0 entries)
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Wikisource
(0 entries)
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Wikiversity
(0 entries)
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Wikivoyage
(0 entries)
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Wiktionary
(0 entries)
edit
Multilingual sites
(1 entry)
edit
commonswiki
Category:Apolipoprotein B
Retrieved from "
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