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C[C@@H]1C[C@@H]([C@H]([C@@H](O1)O[C@H]2[C@H](C[C@@]3(CO3)C(=O)[C@@H]([C@H]([C@H]([C@H](OC(=O)[C@@H]([C@H]([C@@H]2C)O[C@H]4C[C@@H]([C@H]([C@@H](O4)C)O)OC)C)C)C)O)C)C)O)N(C)C

0 references

defined daily dose

1gram

route of administration

oral administration

1 reference

reference URL

https://www.whocc.no/atc_ddd_index/?code=J01FA05

found in taxon

Streptomyces antibioticus

18 references

stated in

Streptomyces antibioticus contains at least three oleandomycin-resistance determinants, one of which shows similarity with proteins of the ABC-transporter superfamily.

stated in

Purification and characterization of an extracellular enzyme from Streptomyces antibioticus that converts inactive glycosylated oleandomycin into the active antibiotic

stated in

Interaction between ATP, oleandomycin and the OleB ATP-binding cassette transporter of Streptomyces antibioticus involved in oleandomycin secretion

stated in

Two glycosyltransferases and a glycosidase are involved in oleandomycin modification during its biosynthesis by Streptomyces antibioticus

stated in

Identification and antibacterial activity of a new oleandomycin derivative from Streptomyces antibioticus

stated in

A cytochrome P450-like gene possibly involved in oleandomycin biosynthesis byStreptomyces antibioticus

stated in

Characterization of the ATPase activity of the N-terminal nucleotide binding domain of an ABC transporter involved in oleandomycin secretion by Streptomyces antibioticus

stated in

Biosynthesis of oleandomycin by Streptomyces antibioticus: influence of nutritional conditions and development of resistance

stated in

Functional analysis of OleY L-oleandrosyl 3-O-methyltransferase of the oleandomycin biosynthetic pathway in Streptomyces antibioticus

stated in

Biosynthesis of the macrolide oleandomycin by Streptomyces antibioticus. Purification and kinetic characterization of an oleandomycin glucosyltransferase

stated in

Characterisation of a Streptomyces antibioticus gene encoding a type I polyketide synthase which has an unusual coding sequence

stated in

Identification and expression of genes involved in biosynthesis of L-oleandrose and its intermediate L-olivose in the oleandomycin producer Streptomyces antibioticus

stated in

Analysis of a Streptomyces antibioticus chromosomal region involved in oleandomycin biosynthesis, which encodes two glycosyltransferases responsible for glycosylation of the macrolactone ring

stated in

Interspecies complementation in Saccharopolyspora erythraea : elucidation of the function of oleP1, oleG1 and oleG2 from the oleandomycin biosynthetic gene cluster of Streptomyces antibioticus and generation of new erythromycin derivatives

stated in

A polyketide biosynthetic gene cluster from Streptomyces antibioticus includes a LysR-type transcriptional regulator

stated in

A second ABC transporter is involved in oleandomycin resistance and its secretion by Streptomyces antibioticus

stated in

Biosynthetic studies on oleandomycin by incorporation of the chemically synthesized aglycones

stated in

Resistance to oleandomycin in Streptomyces antibioticus, the producer organism

Streptomyces cyanogenus

1 reference

stated in

Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis

Streptomyces scabiei

1 reference

stated in

Biosynthesis and evolution of coronafacoyl phytotoxin production in the common scab pathogen Streptomyces scabies.

route of administration

0 references

1 reference

Medical Subject Headings

MeSH descriptor ID

D009827

retrieved

15 March 2018

‎WHO Aware Classification

watch

1 reference

stated in

2023 ‎AWaRe classification‎

schematic

Oleandomycin Synthesis 2.png
1,670 × 1,077; 12 KB

0 references

Oleandomycin synthesis 1.png
1,505 × 2,061; 44 KB

0 references

Identifiers

InChI

InChI=1S/C35H61NO12/c1-16-14-35(15-43-35)32(40)19(4)27(37)18(3)22(7)46-33(41)21(6)31(47-26-13-25(42-11)28(38)23(8)45-26)20(5)30(16)48-34-29(39)24(36(9)10)12-17(2)44-34/h16-31,34,37-39H,12-15H2,1-11H3/t16-,17+,18-,19+,20+,21+,22+,23-,24-,25-,26-,27-,28-,29+,30-,31-,34-,35+/m0/s1

0 references

InChIKey

RZPAKFUAFGMUPI-QESOVKLGSA-N

1 reference

stated in

ChEBI release 2020-09-01

CAS Registry Number

3922-90-5

1 reference

InChIKey

RZPAKFUAFGMUPI-QESOVKLGSA-N

8 April 2021

https://commonchemistry.cas.org/detail?cas_rn=3922-90-5

1 reference

language of work or name

English

title

(3S,5R,6S,7R,8R,11R,12S,13R,14S,15S)-12-[(2,6-dideoxy-3-O-methylhexopyranosyl)oxy]-6-hydroxy-5,7,8,11,13,15-hexamethyl-4,10-dioxo-1,9-dioxaspiro[2.13]hexadec-14-yl 3,4,6-trideoxy-3-(dimethylamino)hexo(English)

retrieved

21 September 2016

PubChem CID

72493

1 reference

matched by identifier from

InChIKey

RZPAKFUAFGMUPI-QESOVKLGSA-N

Reaxys registry number

74476

0 references

ChEBI ID