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Fraunhofer Translational Center Regenerative Therapies TLC-RT

epiCS® epidermis model
© Fraunhofer ISC

Reliable availability of epiCS® epidermis models

OECD-validated tissue models contribute to the safety of cosmetics and pharmaceuticals

more info

© Fraunhofer ISC

3D Bioprinting technology
© RegenHU

3D Bioprinting

Automatized and standardized fabrication of complex living tissues

more info

© RegenHU

Lab Automation and Bioreactor Technologies

The incubator and bioreactor systems developed at TLC-RT have a modular structure and can be adjusted to a wide variety of culture conditions.

more info
Fibers Fibroblasts
© Fraunhofer ISC

Biomaterials

The TLC-RT develops synthetic as well as bio-logically based materials, e. g. (μ- and nano-) particles, fibers, coatings for regenerative medicine, tissue engineering and diagnostics. One of the core tasks is to cover the entire value chain, starting from R&D-tasks over process up-scaling, pre-clinic evaluation to the clinical phases.

more info

© Fraunhofer ISC

Clinical Development

The production of novel drugs and medical devices is subject to high quality requirements. By fulfilling current regulatory guidelines, the TLC-RT ensures the highest level of patient safety for these new, innovative therapies.

more info

Test Systems and 3D Tissue Models

3D tissue models includes model systems of healthy and diseased organs to study pathogenic mechanisms and to test and evaluate new drugs. Picture shows a full skin model.

more info

 

© Fraunhofer ISC / freepik

Innovative research into medicinal plants

Incollaboration with WALA, the Translational Center at Fraunhofer ISC is developing anovel conjunctival model that enables theprecise analysis of inflammatory processes on the surface of the eye. Robust and scalable test systems allow active ingredients and complex drugs to be investigated under controlled but application-relevant conditions.

Are you working on similar topics? We would be happy to support you!

 

© Fraunhofer ISC

Stromal Scaffold

Our innovative, patented 3D fibrous polyamide membrane forstromal in vitro tissue models offers a biomimetic structure with high porosity and bioactivity. It supports cell migration and the synthesis of human tissue.

Thisversatile solution is suitable formodels such as skin, small intestine andcolon andenables animal-free research.

Further information is available here in the PDF for download.

 

© unsplash

Sustainable biogenic materials

Silicic acids, which are found in rice and bamboo, are important for our lives because they have a biostimulating effect on the body and the environment. At Fraunhofer ISC,sustainable, biodegradable materials are being developed from silicic acid that accelerate the body's regeneration and promote health. Dr. Bastian Christ will be glad to tell you more about the sustainable synthesis of biodegradable materials for life science applications!

 

© Fraunhofer ISC

Reliable availability of epiCS® epidermis models

The Fraunhofer Translation Center for Regenerative Therapies (TLC-RT) is taking overepiCS® technology from Henkel AG & Co. KGaA, ensuring the availability of internationally standardized epidermis models. TheseOECD-validated tissue models offer a reliable alternative for evaluating skin reactions to chemical substances and contribute to the safety of cosmetics and pharmaceuticals.

 

© freepik

Article SOFW Journal /29.1.2025

Sustainable beauty

The ISC biomaterial team is generating abioresorbable RENACER® material platform for anovel vegan, biodegradable hair fixative from IPPM Technologies GmbH.

3D Bioprinting Technology

for automatized and standardized fabrication of complex living tissues

Analysis of the effect of plant oils

Together with its research partner Kneipp, the TLC-RT team is investigatingprotective as well as regenerative effects of various plant oils onin vitro skin models developed in-house. Thesescreenings can be carried outquickly, flexibly andwithout animal testing.

    Fields of Activity

     

    © K. Dobberke for Fraunhofer ISC

    Biomaterials

    • 3D Bioprinting
    • Regenerative Biomaterials
    • In vitro and in vivo diagnostics
    • Drug Delivery and Future Technologies
     

    © K. Dobberke for Fraunhofer ISC

    Lab Automation and Bioreactor Technologies

     

    © K. Dobberke for Fraunhofer ISC

    In vitro Test Systems

    • Standardizedin vitro test systems
    • Disease models
    • hiPSC technologies

    Newsletter
    from Fraunhofer ISC

    Our newsletters keep you up to date on the latest developments and offers at our institute.


    Whether research projects, workshops, or events − if you would like to receive information about Fraunhofer ISC activities three to four times a year by e-mail, please subscribe to our

    Email Newsletter


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    Linkedin Newsletter

      Your local contact

      Florian Groeber-Becker

      Contact Press / Media

      Prof. Dr. Florian Groeber-Becker

      Director of TLC-RT

      Fraunhofer Translational Center Regenerative Therapies TLC-RT
      Röntgenring 12
      97070 Würzburg, Germany

      Phone + 49 931 4100-136

      • Send email
      • florian.groeber-becker@isc.fraunhofer.de
      Sofia Dembski

      Contact Press / Media

      Dr. Sofia Dembski

      Deputy Director of TLC-RT / Head of Biomaterials

      Fraunhofer Translational Center Regenerative Therapies TLC-RT
      Neunerplatz 2
      97082 Würzburg, Germany

      Phone +49 931 4100-516


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