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General

Preferred name

TASQUINIMOD

Synonyms

ABR-215050()

LAQUINIMOD()

P&D ID

PD016202

CAS

254964-60-8

Tags

available

drug candidate

Drug indication

Prostate cancer

Drug Status

withdrawn

investigational

Max Phase

3.0

Structure

Probe scores

P&D probe-likeness score

[[ v.score ]]%

Structure formats

[[ format ]]

[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]

Description

(extracted from source data)

DESCRIPTION Tasquinimod is an orally active allosteric inhibitor of HDAC4 . It has antiangiogenic effects. (GtoPdb)

DESCRIPTION Highly potent and selective HIV-1 protease inhibitor (Tocris Bioactive Compound Library)

DESCRIPTION Tasquinimod is a quinoline-3-carboxamide linomide analogue with antiangiogenic and potential antineoplastic activities. Tasquinimod has been shown to decrease blood vessel density but the exact mechanism of action is not known. This agent has also been shown to augment the antineoplastic effects of docetaxel and androgen ablation in a murine model of prostate cancer involving human prostate cancer xenografts. (BOC Sciences Bioactive Compounds)