- Jan 19 Jan Commelin, Dutch botanist and director of Hortus Botanicus, Amsterdam, dies at 62
- Feb 24 Antimo Liberati, Italian composer, dies at 74
- Mar 25 Gerardus Blasius, Flemish anatomist, dies at about 66
- Apr 14 Carlos de Gurrea, Spanish viceroy (Spanish Netherlands), dies
- May 18 Elias Ashmole, English antiquarian & collector (Ashmolean Museum), dies at 74
- Jun 10 Bridget Bishop, American woman accused of witchcraft who was 1st person to be hanged as a result of the Salem witch trials at 60
- Jul 23 Gilles Ménage, French scholar, dies at 78
- Oct 12 Giovanni Battista Vitali, Italian composer, dies at 60
- Nov 6 Gédéon Tallemant des Réaux, French writer (Historiettes), dies at 73
- Nov 14 Christoph Bernhard, German baroque composer, dies at 64
- Nov 19 Georg Friedrich of Waldeck, Dutch-German prince and Field Marshall (commanded Dutch States Army and German forces), dies at 72
- Nov 19 Thomas Shadwell, English poet and playwright (2nd Poet Laureate 1689-92), dies at about 50
- Dec 9 William Mountfort, English actor and dramatist, dies at approximately 38
- Dec 18 Veit Ludwig von Seckendorff, German statesman (b. 1626)