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Online ISSN: 1949-2553

Oncotarget

Journal Content

Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science.

Its scope is unique. The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases.The term was introduced in the inaugural Editorial,Introducing Oncotarget.

As of January 1, 2022,Oncotarget has shifted to a continuous publishing model. Papers will now be published continuously within yearly volumes in their final and complete form and then quickly released to Pubmed.

Publication Alerts

Subscribe to receive alerts once a paper has been published by Oncotarget.

Oncoscience

Oncoscience Logo

Oncoscience is a peer-reviewed, open-access journal dedicated to cancer research without financial barriers. It is a unique journal that provides FREE publication and access for both authors and readers. Oncoscience is indexed and archived by PubMed and PMC. It is recognized by Impact Journals as a philanthropic endeavor.

SSP 47th Annual Meeting

AACR Annual Meeting 2025

Post-Publication Promotion

Impact Journals, LLC is the publisher of Oncotarget:www.impactjournals.com.

Impact Journals is a member of theWellcome Trust List of Compliant Publishers.

Impact Journals is a member of theSociety for Scholarly Publishing.

On December 23, 2022, Oncotarget server experienced a DDoS attack. As a result, Oncotarget site was inaccessible for a few hours. Oncotarget team swiftly dealt with the situation and took it under control.This malicious action will be reported to the FBI.

Current Volume

Cover for Oncotarget Issue V16N1

This Month's Popular DOIs
(Crossref resolutions)

10.18632/ONCOTARGET.23208
10.18632/ONCOTARGET.6429
10.18632/ONCOTARGET.9859
10.18632/ONCOTARGET.13553
10.18632/ONCOTARGET.14401
10.18632/ONCOTARGET.15422
10.18632/ONCOTARGET.16407
10.18632/ONCOTARGET.19087

Most popular Oncotarget DOIs, measured by the number of times each DOI was successfully resolved.

Most Popular DOIs Published in 2024
(Crossref Data)

Targeting WNT5B and WNT10B in osteosarcoma
10.18632/ONCOTARGET.28617
Next-generation vaccines are showing promise against glioblastoma
10.18632/ONCOTARGET.28636
The gut barrier as a gatekeeper in colorectal cancer treatment
10.18632/ONCOTARGET.28634
Regorafenib synergizes with TAS102 against multiple gastrointestinal cancers and overcomes cancer stemness, trifluridine-induced angiogenesis, ERK1/2 and STAT3 signaling regardless of KRAS or BRAF mutational status
10.18632/ONCOTARGET.28602

Top-10 Most Popular DOIs of 2024
(Crossref Data)

T-2 mycotoxin: toxicological effects and decontamination strategies
10.18632/ONCOTARGET.15422
High infiltration of CD68+ macrophages is associated with poor prognoses of head and neck squamous cell carcinoma patients and is influenced by human papillomavirus
10.18632/ONCOTARGET.24306
Biological effects and epidemiological consequences of arsenic exposure, and reagents that can ameliorate arsenic damagein vivo
10.18632/ONCOTARGET.17745
Elevated Orai1 expression mediates tumor-promoting intracellular Ca2+ oscillations in human esophageal squamous cell carcinoma
10.18632/ONCOTARGET.1903
Model driven optimization of antiangiogenics + cytotoxics combination: application to breast cancer mice treated with bevacizumab + paclitaxel doublet leads to reduced tumor growth and fewer metastasis
10.18632/ONCOTARGET.15484
Generation of V α13/β21+T cell specific target CML cells by TCR gene transfer
10.18632/ONCOTARGET.12441
Association of high microvessel αvβ3 and low PTEN with poor outcome in stage 3 neuroblastoma: rationale for using first in class dual PI3K/BRD4 inhibitor, SF1126
10.18632/ONCOTARGET.13386
Curcumin combined with FAPαc vaccine elicits effective antitumor response by targeting indolamine-2,3-dioxygenase and inhibiting EMT induced by TNF-α in melanoma
10.18632/ONCOTARGET.4577
FAM83D associates with high tumor recurrence after liver transplantation involving expansion of CD44+ carcinoma stem cells
10.18632/ONCOTARGET.12715
Genetic disruption of calpain-1 and calpain-2 attenuates tumorigenesis in mouse models of HER2+ breast cancer and sensitizes cancer cells to doxorubicin and lapatinib
10.18632/ONCOTARGET.26078

Milestones in Modern Scholarly Publishing

On August 25, 2022, the Office of Science and Technology Policy announced a new government policy legislating the immediate public release of all United States-funded research publications by 2025.Learn more here andhere.

On May 23, 2023, the Council of the European Union adopted conclusions on high-quality, transparent, open, trustworthy, and equitable scholarly publishing. The Council calls for immediate and unrestricted open access to publishing research involving public funds.Learn more.

Oncotarget.org: Blog Posts on
New & Trending Papers

Oncotarget.org
Latest articles about new and trending papers published by Oncotarget

Oncotarget.net: Latest Insights
From Our Authors

Oncotarget.org
Interviews and testimonials from authors who publish with Oncotarget

October 16, 2018

View Archive »

About The Cover

The cover for issue 81 of Oncotarget features Figure 1, "Molecular Mechanisms of Autophagy," byServante, et al.

Table of Contents

News

V-ATPase in cancer progression: Two sides of the same coin

V-ATPase in cancer progression: Two sides of the same coin

https://doi.org/10.18632/oncotarget.26218

Mohd Saqib, and Bibhuti B. Mishra
35197-35198
PDF |  How to cite

Clinical application of cfDNA: moving in the right direction, but still a long way to go

Clinical application of cfDNA: moving in the right direction, but still a long way to go

https://doi.org/10.18632/oncotarget.26224

Shehara Mendis, and Jonathan M. Loree
35199-35200
PDF |  How to cite

Editorial

Mutant molecular chaperone activates cytokine receptor as a homomultimer

Mutant molecular chaperone activates cytokine receptor as a homomultimer

https://doi.org/10.18632/oncotarget.26221

Marito Araki, and Norio Komatsu
35201-35202
PDF |  How to cite

ASXL1 as a critical regulator of epigenetic marks and therapeutic potential of mutated cells

ASXL1 as a critical regulator of epigenetic marks and therapeutic potential of mutated cells

https://doi.org/10.18632/oncotarget.26230

Daichi Inoue,Takeshi Fujino, and Toshio Kitamura
35203-35204
PDF |  How to cite

Rise of the specialized onco-ribosomes

Rise of the specialized onco-ribosomes

https://doi.org/10.18632/oncotarget.26231

Kim R. Kampen,Sergey O. Sulima, and Kim De Keersmaecker
35205-35206
PDF |  How to cite

Research Papers

Biothiols and oxidative stress markers and polymorphisms ofTOMM40 andAPOC1 genes in Alzheimer's disease patients

Biothiols and oxidative stress markers and polymorphisms ofTOMM40 andAPOC1 genes in Alzheimer's disease patients

https://doi.org/10.18632/oncotarget.26184

Michal Prendecki,Jolanta Florczak-Wyspianska,Marta Kowalska,Jan Ilkowski,Teresa Grzelak,Katarzyna Bialas,Malgorzata Wiszniewska,Wojciech Kozubski, and Jolanta Dorszewska
35207-35225
Abstract |  PDF |  HTML |  Supplementary Information |  How to cite

The potent and selective cyclin-dependent kinases 4 and 6 inhibitor ribociclib (LEE011) is a versatile combination partner in preclinical cancer models

The potent and selective cyclin-dependent kinases 4 and 6 inhibitor ribociclib (LEE011) is a versatile combination partner in preclinical cancer models

https://doi.org/10.18632/oncotarget.26215

Sunkyu Kim,Ralph Tiedt,Alice Loo,Thomas Horn,Scott Delach,Steven Kovats,Kristy Haas,Barbara Schacher Engstler,Alexander Cao,Maria Pinzon-Ortiz,Iain Mulford,Michael G. Acker,Rajiv Chopra,Christopher Brain,Emmanuelle di Tomaso,William R. Sellers, and Giordano Caponigro
35226-35240
Abstract |  PDF |  HTML |  Supplementary Information |  How to cite

Immortalized murine fibroblast cell lines are refractory to reprogramming to pluripotent state

Immortalized murine fibroblast cell lines are refractory to reprogramming to pluripotent state

https://doi.org/10.18632/oncotarget.26235

Elena V. Skvortsova,Sergey A. Sinenko, and Alexey N. Tomilin
35241-35250
Abstract |  PDF |  HTML |  Supplementary Information |  How to cite

Clinical Research Papers

Integration of stereotactic radiotherapy in the treatment of metastatic colorectal cancer patients: a real practice study with long-term outcome and prognostic factors

Integration of stereotactic radiotherapy in the treatment of metastatic colorectal cancer patients: a real practice study with long-term outcome and prognostic factors

https://doi.org/10.18632/oncotarget.25834

Alessandro Ottaiano,Valerio Scotti,Chiara De Divitiis,Monica Capozzi,Carmen Romano,Antonino Cassata,Rossana Casaretti,Lucrezia Silvestro,Anna Nappi,Valeria Vicario,Alfonso De Stefano,Salvatore Tafuto,Massimiliano Berretta,Guglielmo Nasti, and Antonio Avallone
35251-35265
Abstract |  PDF |  HTML |  How to cite

Reviews

Chemical modulation of autophagy as an adjunct to chemotherapy in childhood and adolescent brain tumors

Chemical modulation of autophagy as an adjunct to chemotherapy in childhood and adolescent brain tumors

https://doi.org/10.18632/oncotarget.26186

Juliette Servante,Jasper Estranero,Lisethe Meijer,Rob Layfield, and Richard Grundy
35266-35277
Abstract |  PDF |  HTML |  How to cite |  Press Release

Case Reports

ROS1-rearranged putative lung adenocarcinoma presenting as carcinoma of unknown primary site: a case report

ROS1-rearranged putative lung adenocarcinoma presenting as carcinoma of unknown primary site: a case report

https://doi.org/10.18632/oncotarget.26233

Masaya Taniwaki,Masahiro Yamasaki,Koto Kawata,Kazuma Kawamoto,Kunihiko Funaishi,Yu Matsumoto,Naoko Matsumoto,Nobuyuki Ohashi, and Noboru Hattori
35278-35282
Abstract |  PDF |  HTML |  How to cite

Corrections

Correction: Tumor driven by gain-of-function HER2 H878Y mutant is highly sensitive to HER2 inhibitor

Correction: Tumor driven by gain-of-function HER2 H878Y mutant is highly sensitive to HER2 inhibitor

https://doi.org/10.18632/oncotarget.26252

Zexi Hu,Yong Hu,Xicheng Liu,Rongwen Xi,Aiqun Zhang,Deruo Liu,Qiang Xie, and Liang Chen
35283-35283
Correction |  PDF |  How to cite

Correction: Overexpression of wildtype EGFR is tumorigenic and denotes a therapeutic target in non-small cell lung cancer

Correction: Overexpression of wildtype EGFR is tumorigenic and denotes a therapeutic target in non-small cell lung cancer

https://doi.org/10.18632/oncotarget.26254

Naiqing Xu,Wenfeng Fang,Libing Mu,Yanna Tang,Lei Gao,Shengxiang Ren,Dengfeng Cao,Lixin Zhou,Aiqun Zhang,Deruo Liu,Caicun Zhou,Kwok-Kin Wong,Lei Yu,Li Zhang, and Liang Chen
35284-35284
Correction |  PDF |  How to cite

Correction: EGFR kinase domain mutation positive lung cancers are sensitive to intrapleural perfusion with hyperthermic chemotherapy (IPHC) complete treatment

Correction: EGFR kinase domain mutation positive lung cancers are sensitive to intrapleural perfusion with hyperthermic chemotherapy (IPHC) complete treatment

https://doi.org/10.18632/oncotarget.26255

Hongjuan Zhang,Cheng Zhan,Ji Ke,Zhiqiang Xue,Aiqun Zhang,Kaifeng Xu,Zhirong Shen,Lei Yu, and Liang Chen
35285-35285
Correction |  PDF |  How to cite

Errata

Erratum: Functional analysis of MKP-1 and MKP-2 in breast cancer tamoxifen sensitivity

Erratum: Functional analysis of MKP-1 and MKP-2 in breast cancer tamoxifen sensitivity

https://doi.org/10.18632/oncotarget.26258

Kelly K. Haagenson,Jessica Wei Zhang,Zhengfan Xu,Malathy P.V. Shekhar, and Gen Sheng Wu
35286-35286
Erratum |  PDF |  How to cite


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