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Online ISSN: 1949-2553

Oncotarget

Journal Content

Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science.

Its scope is unique. The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases.The term was introduced in the inaugural Editorial,Introducing Oncotarget.

As of January 1, 2022,Oncotarget has shifted to a continuous publishing model. Papers will now be published continuously within yearly volumes in their final and complete form and then quickly released to Pubmed.

Publication Alerts

Subscribe to receive alerts once a paper has been published by Oncotarget.

Oncoscience

Oncoscience Logo

Oncoscience is a peer-reviewed, open-access journal dedicated to cancer research without financial barriers. It is a unique journal that provides FREE publication and access for both authors and readers. Oncoscience is indexed and archived by PubMed and PMC. It is recognized by Impact Journals as a philanthropic endeavor.

SSP 47th Annual Meeting

AACR Annual Meeting 2025

Post-Publication Promotion

Impact Journals, LLC is the publisher of Oncotarget:www.impactjournals.com.

Impact Journals is a member of theWellcome Trust List of Compliant Publishers.

Impact Journals is a member of theSociety for Scholarly Publishing.

On December 23, 2022, Oncotarget server experienced a DDoS attack. As a result, Oncotarget site was inaccessible for a few hours. Oncotarget team swiftly dealt with the situation and took it under control.This malicious action will be reported to the FBI.

Current Volume

Cover for Oncotarget Issue V16N1

This Month's Popular DOIs
(Crossref resolutions)

10.18632/ONCOTARGET.23208
10.18632/ONCOTARGET.6429
10.18632/ONCOTARGET.9859
10.18632/ONCOTARGET.13553
10.18632/ONCOTARGET.14401
10.18632/ONCOTARGET.15422
10.18632/ONCOTARGET.16407
10.18632/ONCOTARGET.19087

Most popular Oncotarget DOIs, measured by the number of times each DOI was successfully resolved.

Most Popular DOIs Published in 2024
(Crossref Data)

Targeting WNT5B and WNT10B in osteosarcoma
10.18632/ONCOTARGET.28617
Next-generation vaccines are showing promise against glioblastoma
10.18632/ONCOTARGET.28636
The gut barrier as a gatekeeper in colorectal cancer treatment
10.18632/ONCOTARGET.28634
Regorafenib synergizes with TAS102 against multiple gastrointestinal cancers and overcomes cancer stemness, trifluridine-induced angiogenesis, ERK1/2 and STAT3 signaling regardless of KRAS or BRAF mutational status
10.18632/ONCOTARGET.28602

Top-10 Most Popular DOIs of 2024
(Crossref Data)

T-2 mycotoxin: toxicological effects and decontamination strategies
10.18632/ONCOTARGET.15422
High infiltration of CD68+ macrophages is associated with poor prognoses of head and neck squamous cell carcinoma patients and is influenced by human papillomavirus
10.18632/ONCOTARGET.24306
Biological effects and epidemiological consequences of arsenic exposure, and reagents that can ameliorate arsenic damagein vivo
10.18632/ONCOTARGET.17745
Elevated Orai1 expression mediates tumor-promoting intracellular Ca2+ oscillations in human esophageal squamous cell carcinoma
10.18632/ONCOTARGET.1903
Model driven optimization of antiangiogenics + cytotoxics combination: application to breast cancer mice treated with bevacizumab + paclitaxel doublet leads to reduced tumor growth and fewer metastasis
10.18632/ONCOTARGET.15484
Generation of V α13/β21+T cell specific target CML cells by TCR gene transfer
10.18632/ONCOTARGET.12441
Association of high microvessel αvβ3 and low PTEN with poor outcome in stage 3 neuroblastoma: rationale for using first in class dual PI3K/BRD4 inhibitor, SF1126
10.18632/ONCOTARGET.13386
Curcumin combined with FAPαc vaccine elicits effective antitumor response by targeting indolamine-2,3-dioxygenase and inhibiting EMT induced by TNF-α in melanoma
10.18632/ONCOTARGET.4577
FAM83D associates with high tumor recurrence after liver transplantation involving expansion of CD44+ carcinoma stem cells
10.18632/ONCOTARGET.12715
Genetic disruption of calpain-1 and calpain-2 attenuates tumorigenesis in mouse models of HER2+ breast cancer and sensitizes cancer cells to doxorubicin and lapatinib
10.18632/ONCOTARGET.26078

Milestones in Modern Scholarly Publishing

On August 25, 2022, the Office of Science and Technology Policy announced a new government policy legislating the immediate public release of all United States-funded research publications by 2025.Learn more here andhere.

On May 23, 2023, the Council of the European Union adopted conclusions on high-quality, transparent, open, trustworthy, and equitable scholarly publishing. The Council calls for immediate and unrestricted open access to publishing research involving public funds.Learn more.

Oncotarget.org: Blog Posts on
New & Trending Papers

Oncotarget.org
Latest articles about new and trending papers published by Oncotarget

Oncotarget.net: Latest Insights
From Our Authors

Oncotarget.org
Interviews and testimonials from authors who publish with Oncotarget

September 18, 2018

View Archive »

About The Cover

The cover for issue 73 of Oncotarget features Figure 2, "Benefit of CAD in TZ tumor identification," byGaur, et al.

Table of Contents

News

Genetic alterations associated with ALTered telomeres

Genetic alterations associated with ALTered telomeres

https://doi.org/10.18632/oncotarget.26111

Jacqueline A. Brosnan-Cashman,Mindy K. Graham, and Christopher M. Heaphy
33739-33740
PDF |  How to cite

Editorial

Systemic therapy for hepatocellular carcinoma: trial enrichment does not guarantee success

Systemic therapy for hepatocellular carcinoma: trial enrichment does not guarantee success

https://doi.org/10.18632/oncotarget.26052

Leonardo G. Da Fonseca,Maria Reig, and Jordi Bruix
33741-33742
PDF |  How to cite

Genomic mechanisms of immune evasion in colorectal cancer: from discovery to clinical practice

Genomic mechanisms of immune evasion in colorectal cancer: from discovery to clinical practice

https://doi.org/10.18632/oncotarget.26105

Catherine S. Grasso, and Marios Giannakis
33743-33744
PDF |  How to cite

Research Papers

Nuclear PKM2 promotes the progression of oral squamous cell carcinoma by inducing EMT and post-translationally repressing TGIF2

Nuclear PKM2 promotes the progression of oral squamous cell carcinoma by inducing EMT and post-translationally repressing TGIF2

https://doi.org/10.18632/oncotarget.25850

Fumie Tanaka,Shohei Yoshimoto,Kazuhiko Okamura,Tetsuro Ikebe, and Shuichi Hashimoto
33745-33761
Abstract |  PDF |  HTML |  Supplementary Information |  How to cite

Development of parallel reaction monitoring (PRM)-based quantitative proteomics applied to HER2-Positive breast cancer

Development of parallel reaction monitoring (PRM)-based quantitative proteomics applied to HER2-Positive breast cancer

https://doi.org/10.18632/oncotarget.26031

Mathilde Guerin,Anthony Gonçalves,Yves Toiron,Emilie Baudelet,Matthieu Pophillat,Samuel Granjeaud,Patrick Fourquet,William Jacot,Carole Tarpin,Renaud Sabatier,Emilie Agavnian,Pascal Finetti,José Adelaide,Daniel Birnbaum,Christophe Ginestier,Emmanuelle Charafe-Jauffret,Patrice Viens,François Bertucci,Jean-Paul Borg, and Luc Camoin
33762-33777
Abstract |  PDF |  HTML |  Supplementary Information |  How to cite

The close relationship between heparanase and epithelial mesenchymal transition in gastric signet-ring cell adenocarcinoma

The close relationship between heparanase and epithelial mesenchymal transition in gastric signet-ring cell adenocarcinoma

https://doi.org/10.18632/oncotarget.26042

Shahid Shah,Caroline Fourgeaud,Simon Derieux,Shahsoltan Mirshahi,Geneviève Contant,Cynthia Pimpie,Rea Lo Dico,Jeannette Soria,Marc Pocard, and Massoud Mirshahi
33778-33787
Abstract |  PDF |  HTML |  Supplementary Information |  How to cite

RND1 regulates migration of human glioblastoma stem-like cells according to their anatomical localization and defines a prognostic signature in glioblastoma

RND1 regulates migration of human glioblastoma stem-like cells according to their anatomical localization and defines a prognostic signature in glioblastoma

https://doi.org/10.18632/oncotarget.26082

Sabrina Boyrie,Caroline Delmas,Anthony Lemarié,Vincent Lubrano,Perrine Dahan,Laure Malric,José Luis,Julia Gilhodes,Marie Tosolini,Laetitia Mouly,Maxime Lehmann,Christine Toulas,Elizabeth Cohen-Jonathan Moyal, and Sylvie Monferran
33788-33803
Abstract |  PDF |  HTML |  Supplementary Information |  How to cite

Can computer-aided diagnosis assist in the identification of prostate cancer on prostate MRI? a multi-center, multi-reader investigation

Can computer-aided diagnosis assist in the identification of prostate cancer on prostate MRI? a multi-center, multi-reader investigation

https://doi.org/10.18632/oncotarget.26100

Sonia Gaur,Nathan Lay,Stephanie A. Harmon,Sreya Doddakashi,Sherif Mehralivand,Burak Argun,Tristan Barrett,Sandra Bednarova,Rossanno Girometti,Ercan Karaarslan,Ali Riza Kural,Aytekin Oto,Andrei S. Purysko,Tatjana Antic,Cristina Magi-Galluzzi,Yesim Saglican,Stefano Sioletic,Anne Y. Warren,Leonardo Bittencourt,Jurgen J. Fütterer,Rajan T. Gupta,Ismail Kabakus,Yan Mee Law,Daniel J. Margolis,Haytham Shebel,Antonio C. Westphalen,Bradford J. Wood,Peter A. Pinto,Joanna H. Shih,Peter L. Choyke,Ronald M. Summers, and Baris Turkbey
33804-33817
Abstract |  PDF |  HTML |  Supplementary Information |  How to cite |  Press Release

Mitochondria as oncotarget: a comparison between the tetracycline analogs doxycycline and COL-3

Mitochondria as oncotarget: a comparison between the tetracycline analogs doxycycline and COL-3

https://doi.org/10.18632/oncotarget.26107

Margherita Protasoni,Albert M. Kroon, and Jan-Willem Taanman
33818-33831
Abstract |  PDF |  HTML |  How to cite

Synthetic lethality of the ALDH3A1 inhibitor dyclonine and xCT inhibitors in glutathione deficiency-resistant cancer cells

Synthetic lethality of the ALDH3A1 inhibitor dyclonine and xCT inhibitors in glutathione deficiency-resistant cancer cells

https://doi.org/10.18632/oncotarget.26112

Shogo Okazaki,Subaru Shintani,Yuki Hirata,Kentaro Suina,Takashi Semba,Juntaro Yamasaki,Kiyoko Umene,Miyuki Ishikawa,Hideyuki Saya, and Osamu Nagano
33832-33843
Abstract |  PDF |  HTML |  Supplementary Information |  How to cite

The anti-mesothelin monoclonal antibody amatuximab enhances the anti-tumor effect of gemcitabine against mesothelin-high expressing pancreatic cancer cells in a peritoneal metastasis mouse model

The anti-mesothelin monoclonal antibody amatuximab enhances the anti-tumor effect of gemcitabine against mesothelin-high expressing pancreatic cancer cells in a peritoneal metastasis mouse model

https://doi.org/10.18632/oncotarget.26117

Tatsuzo Mizukami,Hirofumi Kamachi,Yuki Fujii,Fumihiko Matsuzawa,Takahiro Einama,Futoshi Kawamata,Nozomi Kobayashi,Yutaka Hatanaka, and Akinobu Taketomi
33844-33852
Abstract |  PDF |  HTML |  Supplementary Information |  How to cite
Special Collection ToC

Toxicity of JQ1 in neuronal derivatives of human umbilical cord mesenchymal stem cells

Toxicity of JQ1 in neuronal derivatives of human umbilical cord mesenchymal stem cells

https://doi.org/10.18632/oncotarget.26127

Shreeya Bakshi,Christina McKee,Keegan Walker,Christina Brown, and G. Rasul Chaudhry
33853-33864
Abstract |  PDF |  HTML |  How to cite

Corrections

Correction: The ratio of STAT1 to STAT3 expression is a determinant of colorectal cancer growth

Correction: The ratio of STAT1 to STAT3 expression is a determinant of colorectal cancer growth

https://doi.org/10.18632/oncotarget.26156

Harini Nivarthi,Claire Gordziel,Madeleine Themanns,Nina Kramer,Markus Eberl,Björn Rabe,Michaela Schlederer,Stefan Rose-John,Thomas Knösel,Lukas Kenner,Patricia Freund,Fritz Aberger,Xiaonan Han,Robert Kralovics,Helmut Dolznig,Susanne Jennek,Karlheinz Friedrich, and Richard Moriggl
33865-33865
Correction |  PDF |  How to cite

Errata

Erratum: Drug-Targeted Inhibition of Peroxisome Proliferator-Activated Receptor-gamma Enhances the Chemopreventive Effect of Anti-Estrogen Therapy

Erratum: Drug-Targeted Inhibition of Peroxisome Proliferator-Activated Receptor-gamma Enhances the Chemopreventive Effect of Anti-Estrogen Therapy

https://doi.org/10.18632/oncotarget.26161

Hongyan Yuan,Levy Kopelovich,Yuzhi Yin,Jin Lu, and Robert I. Glazer
33866-33866
Erratum |  PDF |  How to cite


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