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Online ISSN: 1949-2553

Oncotarget

Journal Content

Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science.

Its scope is unique. The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases.The term was introduced in the inaugural Editorial,Introducing Oncotarget.

As of January 1, 2022,Oncotarget has shifted to a continuous publishing model. Papers will now be published continuously within yearly volumes in their final and complete form and then quickly released to Pubmed.

Publication Alerts

Subscribe to receive alerts once a paper has been published by Oncotarget.

Oncoscience

Oncoscience Logo

Oncoscience is a peer-reviewed, open-access journal dedicated to cancer research without financial barriers. It is a unique journal that provides FREE publication and access for both authors and readers. Oncoscience is indexed and archived by PubMed and PMC. It is recognized by Impact Journals as a philanthropic endeavor.

SSP 47th Annual Meeting

AACR Annual Meeting 2025

Post-Publication Promotion

Impact Journals, LLC is the publisher of Oncotarget:www.impactjournals.com.

Impact Journals is a member of theWellcome Trust List of Compliant Publishers.

Impact Journals is a member of theSociety for Scholarly Publishing.

On December 23, 2022, Oncotarget server experienced a DDoS attack. As a result, Oncotarget site was inaccessible for a few hours. Oncotarget team swiftly dealt with the situation and took it under control.This malicious action will be reported to the FBI.

Current Volume

Cover for Oncotarget Issue V16N1

This Month's Popular DOIs
(Crossref resolutions)

10.18632/ONCOTARGET.23208
10.18632/ONCOTARGET.6429
10.18632/ONCOTARGET.9859
10.18632/ONCOTARGET.13553
10.18632/ONCOTARGET.14401
10.18632/ONCOTARGET.15422
10.18632/ONCOTARGET.16407
10.18632/ONCOTARGET.19087

Most popular Oncotarget DOIs, measured by the number of times each DOI was successfully resolved.

Most Popular DOIs Published in 2024
(Crossref Data)

Targeting WNT5B and WNT10B in osteosarcoma
10.18632/ONCOTARGET.28617
Next-generation vaccines are showing promise against glioblastoma
10.18632/ONCOTARGET.28636
The gut barrier as a gatekeeper in colorectal cancer treatment
10.18632/ONCOTARGET.28634
Regorafenib synergizes with TAS102 against multiple gastrointestinal cancers and overcomes cancer stemness, trifluridine-induced angiogenesis, ERK1/2 and STAT3 signaling regardless of KRAS or BRAF mutational status
10.18632/ONCOTARGET.28602

Top-10 Most Popular DOIs of 2024
(Crossref Data)

T-2 mycotoxin: toxicological effects and decontamination strategies
10.18632/ONCOTARGET.15422
High infiltration of CD68+ macrophages is associated with poor prognoses of head and neck squamous cell carcinoma patients and is influenced by human papillomavirus
10.18632/ONCOTARGET.24306
Biological effects and epidemiological consequences of arsenic exposure, and reagents that can ameliorate arsenic damagein vivo
10.18632/ONCOTARGET.17745
Elevated Orai1 expression mediates tumor-promoting intracellular Ca2+ oscillations in human esophageal squamous cell carcinoma
10.18632/ONCOTARGET.1903
Model driven optimization of antiangiogenics + cytotoxics combination: application to breast cancer mice treated with bevacizumab + paclitaxel doublet leads to reduced tumor growth and fewer metastasis
10.18632/ONCOTARGET.15484
Generation of V α13/β21+T cell specific target CML cells by TCR gene transfer
10.18632/ONCOTARGET.12441
Association of high microvessel αvβ3 and low PTEN with poor outcome in stage 3 neuroblastoma: rationale for using first in class dual PI3K/BRD4 inhibitor, SF1126
10.18632/ONCOTARGET.13386
Curcumin combined with FAPαc vaccine elicits effective antitumor response by targeting indolamine-2,3-dioxygenase and inhibiting EMT induced by TNF-α in melanoma
10.18632/ONCOTARGET.4577
FAM83D associates with high tumor recurrence after liver transplantation involving expansion of CD44+ carcinoma stem cells
10.18632/ONCOTARGET.12715
Genetic disruption of calpain-1 and calpain-2 attenuates tumorigenesis in mouse models of HER2+ breast cancer and sensitizes cancer cells to doxorubicin and lapatinib
10.18632/ONCOTARGET.26078

Milestones in Modern Scholarly Publishing

On August 25, 2022, the Office of Science and Technology Policy announced a new government policy legislating the immediate public release of all United States-funded research publications by 2025.Learn more here andhere.

On May 23, 2023, the Council of the European Union adopted conclusions on high-quality, transparent, open, trustworthy, and equitable scholarly publishing. The Council calls for immediate and unrestricted open access to publishing research involving public funds.Learn more.

Oncotarget.org: Blog Posts on
New & Trending Papers

Oncotarget.org
Latest articles about new and trending papers published by Oncotarget

Oncotarget.net: Latest Insights
From Our Authors

Oncotarget.org
Interviews and testimonials from authors who publish with Oncotarget

August 28, 2018

View Archive »

About The Cover

The cover for issue 67 of Oncotarget features Figure 4, "ROC curve analysis of urinary EV mRNA markers in various stages of bladder cancer," byMurakami, et al.

Table of Contents

News

Rituximab mechanisms of action in B-CLL: a new piece of the puzzle

Rituximab mechanisms of action in B-CLL: a new piece of the puzzle

https://doi.org/10.18632/oncotarget.26016

Hervé Watier
32732-32733
PDF |  How to cite

Acquired palbociclib resistance in KRAS-mutant lung cancer

Acquired palbociclib resistance in KRAS-mutant lung cancer

https://doi.org/10.18632/oncotarget.26027

Charles J. Sherr
32734-32735
PDF |  How to cite

Research Papers

PKCι and YAP1 are crucial in promoting pancreatic tumorigenesis

PKCι and YAP1 are crucial in promoting pancreatic tumorigenesis

https://doi.org/10.18632/oncotarget.25127

Peipei Wang,Dapeng Wei,Hongmei Zhang,Jiao Chen,Dingding Zhang,Suthakar Ganapathy,Pauline Isakson,Changyan Chen, and Tongbo Zhu
32736-32750
Abstract |  PDF |  HTML |  How to cite

A novel, nontoxic iron chelator, super-polyphenol, effectively induces apoptosis in human cancer cell lines

A novel, nontoxic iron chelator, super-polyphenol, effectively induces apoptosis in human cancer cell lines

https://doi.org/10.18632/oncotarget.25973

Toshiaki Ohara,Yasuko Tomono,Xing Boyi,Sun Yingfu,Kazuhiro Omori, and Akihiro Matsukawa
32751-32760
Abstract |  PDF |  HTML |  Supplementary Information |  How to cite

Differential signaling pathway activation in 7,12-dimethylbenz[a] anthracene (DMBA)-treated mammary stem/progenitor cells from species with varying mammary cancer incidence

Differential signaling pathway activation in 7,12-dimethylbenz[a] anthracene (DMBA)-treated mammary stem/progenitor cells from species with varying mammary cancer incidence

https://doi.org/10.18632/oncotarget.25988

Melissa M. Ledet,Meghan Oswald,Robyn Anderson, and Gerlinde R. Van de Walle
32761-32774
Abstract |  PDF |  HTML |  Supplementary Information |  How to cite

PLAGL1 gene function during hepatoma cells proliferation

PLAGL1 gene function during hepatoma cells proliferation

https://doi.org/10.18632/oncotarget.25996

Ana F. Vega-Benedetti,Cinthia N. Saucedo,Patrizia Zavattari,Roberta Vanni,Felix Royo,Francisco Llavero,José L. Zugaza, and Luis A. Parada
32775-32794
Abstract |  PDF |  HTML |  How to cite

Thymic stromal lymphopoietin in human pancreatic ductal adenocarcinoma: expression and prognostic significance

Thymic stromal lymphopoietin in human pancreatic ductal adenocarcinoma: expression and prognostic significance

https://doi.org/10.18632/oncotarget.25997

Barbara Vizio,Monica Boita,Carmen Cristiano,Jasenka Mazibrada,Ornella Bosco,Anna Novarino,Adriana Prati,Savino Sciascia,Giovanni Rolla,Libero Ciuffreda,Giuseppe Montrucchio, and Graziella Bellone
32795-32809
Abstract |  PDF |  HTML |  Supplementary Information |  How to cite

Bladder cancer detection by urinary extracellular vesicle mRNA analysis

Bladder cancer detection by urinary extracellular vesicle mRNA analysis

https://doi.org/10.18632/oncotarget.25998

Taku Murakami,Cindy M. Yamamoto,Tomoshige Akino,Hiroshi Tanaka,Nobuyuki Fukuzawa,Hidetaka Suzuki,Takahiro Osawa,Takahiro Tsuji,Toshimori Seki, and Hiroshi Harada
32810-32821
Abstract |  PDF |  HTML |  Supplementary Information |  How to cite |  Press Release

Vitamin C promotes decitabine or azacytidine induced DNA hydroxymethylation and subsequent reactivation of the epigenetically silenced tumour suppressorCDKN1A in colon cancer cells

Vitamin C promotes decitabine or azacytidine induced DNA hydroxymethylation and subsequent reactivation of the epigenetically silenced tumour suppressorCDKN1A in colon cancer cells

https://doi.org/10.18632/oncotarget.25999

Christian Gerecke,Fabian Schumacher,Alexander Edlich,Alexandra Wetzel,Guy Yealland,Lena Katharina Neubert,Bettina Scholtka,Thomas Homann, and Burkhard Kleuser
32822-32840
Abstract |  PDF |  HTML |  How to cite

PAX5A andPAX5B isoforms are both efficient to drive B cell differentiation

PAX5A andPAX5B isoforms are both efficient to drive B cell differentiation

https://doi.org/10.18632/oncotarget.26003

Charlotte Cresson,Sophie Péron,Laura Jamrog,Nelly Rouquié,Nais Prade,Marine Dubois,Sylvie Hébrard,Stéphanie Lagarde,Bastien Gerby,Stéphane J.C. Mancini,Michel Cogné,Eric Delabesse,Laurent Delpy, and Cyril Broccardo
32841-32854
Abstract |  PDF |  HTML |  Supplementary Information |  How to cite

Beyond the 3′UTR binding–microRNA-induced protein truncation via DNA binding

Beyond the 3′UTR binding–microRNA-induced protein truncation via DNA binding

https://doi.org/10.18632/oncotarget.26023

Melanie von Brandenstein,Stephan H. Bernhart,Andreas Pansky,Claudia Richter,Tobias Kohl,Martina Deckert,Axel Heidenreich,Peter F. Stadler,Manuel Montesinos-Rongen, and Jochen W.U. Fries
32855-32867
Abstract |  PDF |  HTML |  Supplementary Information |  How to cite

Identification of a novel gene fusion in ALT positive osteosarcoma

Identification of a novel gene fusion in ALT positive osteosarcoma

https://doi.org/10.18632/oncotarget.26029

Emily Mason-Osann,Anqi Dai,Jess Floro,Ying Jie Lock,Matthew Reiss,Himabindu Gali,Adeline Matschulat,Adam Labadorf, and Rachel Litman Flynn
32868-32880
Abstract |  PDF |  HTML |  Supplementary Information |  How to cite

Corrections

Correction: Increasing TIMP3 expression by hypomethylating agents diminishes soluble MICA, MICB and ULBP2 shedding in acute myeloid leukemia, facilitating NK cell-mediated immune recognition

Correction: Increasing TIMP3 expression by hypomethylating agents diminishes soluble MICA, MICB and ULBP2 shedding in acute myeloid leukemia, facilitating NK cell-mediated immune recognition

https://doi.org/10.18632/oncotarget.26079

Aroa Baragaño Raneros,Alfredo Minguela,Ramon M. Rodriguez,Enrique Colado,Teresa Bernal,Eduardo Anguita,Adela Vasco Mogorron,Alberto Chaparro Gil,Jose Ramon Vidal-Castiñeira,Leonardo Márquez-Kisinousky,Paula Díaz Bulnes,Amelia Martinez Marin,Maria Carmen García Garay,Beatriz Suarez-Alvarez, and Carlos Lopez-Larrea
32881-32881
Correction |  PDF |  How to cite

Correction: The mutational landscape of ocular marginal zone lymphoma identifies frequent alterations inTNFAIP3 followed by mutations inTBL1XR1 andCREBBP

Correction: The mutational landscape of ocular marginal zone lymphoma identifies frequent alterations inTNFAIP3 followed by mutations inTBL1XR1 andCREBBP

https://doi.org/10.18632/oncotarget.26080

Hyunchul Jung,Hae Yong Yoo,Seung Ho Lee,Sohyun Shin,Sang Cheol Kim,Sejoon Lee,Je-Gun Joung,Jae-Yong Nam,Daeun Ryu,Jae Won Yun,Jung Kyoon Choi,Ambarnil Ghosh,Kyeong Kyu Kim,Seok Jin Kim,Won Seog Kim,Woong-Yang Park, and Young-Hyeh Ko
32882-32882
Correction |  PDF |  How to cite


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