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Online ISSN: 1949-2553

Oncotarget

Journal Content

Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science.

Its scope is unique. The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases.The term was introduced in the inaugural Editorial,Introducing Oncotarget.

As of January 1, 2022,Oncotarget has shifted to a continuous publishing model. Papers will now be published continuously within yearly volumes in their final and complete form and then quickly released to Pubmed.

Publication Alerts

Subscribe to receive alerts once a paper has been published by Oncotarget.

Oncoscience

Oncoscience Logo

Oncoscience is a peer-reviewed, open-access journal dedicated to cancer research without financial barriers. It is a unique journal that provides FREE publication and access for both authors and readers. Oncoscience is indexed and archived by PubMed and PMC. It is recognized by Impact Journals as a philanthropic endeavor.

Post-Publication Promotion

Impact Journals, LLC is the publisher of Oncotarget:www.impactjournals.com.

Impact Journals is a member of theWellcome Trust List of Compliant Publishers.

Impact Journals is a member of theSociety for Scholarly Publishing.

On December 23, 2022, Oncotarget server experienced a DDoS attack. As a result, Oncotarget site was inaccessible for a few hours. Oncotarget team swiftly dealt with the situation and took it under control.This malicious action will be reported to the FBI.

Current Volume

Cover for Oncotarget Issue V16N1

This Month's Popular DOIs
(Crossref resolutions)

10.18632/ONCOTARGET.23208
10.18632/ONCOTARGET.6429
10.18632/ONCOTARGET.9859
10.18632/ONCOTARGET.13553
10.18632/ONCOTARGET.14401
10.18632/ONCOTARGET.15422
10.18632/ONCOTARGET.16407
10.18632/ONCOTARGET.19087

Most popular Oncotarget DOIs, measured by the number of times each DOI was successfully resolved.

Most Popular DOIs Published in 2024
(Crossref Data)

Targeting WNT5B and WNT10B in osteosarcoma
10.18632/ONCOTARGET.28617
Next-generation vaccines are showing promise against glioblastoma
10.18632/ONCOTARGET.28636
The gut barrier as a gatekeeper in colorectal cancer treatment
10.18632/ONCOTARGET.28634
Regorafenib synergizes with TAS102 against multiple gastrointestinal cancers and overcomes cancer stemness, trifluridine-induced angiogenesis, ERK1/2 and STAT3 signaling regardless of KRAS or BRAF mutational status
10.18632/ONCOTARGET.28602

Top-10 Most Popular DOIs of 2024
(Crossref Data)

T-2 mycotoxin: toxicological effects and decontamination strategies
10.18632/ONCOTARGET.15422
High infiltration of CD68+ macrophages is associated with poor prognoses of head and neck squamous cell carcinoma patients and is influenced by human papillomavirus
10.18632/ONCOTARGET.24306
Biological effects and epidemiological consequences of arsenic exposure, and reagents that can ameliorate arsenic damagein vivo
10.18632/ONCOTARGET.17745
Elevated Orai1 expression mediates tumor-promoting intracellular Ca2+ oscillations in human esophageal squamous cell carcinoma
10.18632/ONCOTARGET.1903
Model driven optimization of antiangiogenics + cytotoxics combination: application to breast cancer mice treated with bevacizumab + paclitaxel doublet leads to reduced tumor growth and fewer metastasis
10.18632/ONCOTARGET.15484
Generation of V α13/β21+T cell specific target CML cells by TCR gene transfer
10.18632/ONCOTARGET.12441
Association of high microvessel αvβ3 and low PTEN with poor outcome in stage 3 neuroblastoma: rationale for using first in class dual PI3K/BRD4 inhibitor, SF1126
10.18632/ONCOTARGET.13386
Curcumin combined with FAPαc vaccine elicits effective antitumor response by targeting indolamine-2,3-dioxygenase and inhibiting EMT induced by TNF-α in melanoma
10.18632/ONCOTARGET.4577
FAM83D associates with high tumor recurrence after liver transplantation involving expansion of CD44+ carcinoma stem cells
10.18632/ONCOTARGET.12715
Genetic disruption of calpain-1 and calpain-2 attenuates tumorigenesis in mouse models of HER2+ breast cancer and sensitizes cancer cells to doxorubicin and lapatinib
10.18632/ONCOTARGET.26078

Milestones in Modern Scholarly Publishing

On August 25, 2022, the Office of Science and Technology Policy announced a new government policy legislating the immediate public release of all United States-funded research publications by 2025.Learn more here andhere.

On May 23, 2023, the Council of the European Union adopted conclusions on high-quality, transparent, open, trustworthy, and equitable scholarly publishing. The Council calls for immediate and unrestricted open access to publishing research involving public funds.Learn more.

Oncotarget.org: Blog Posts on
New & Trending Papers

Oncotarget.org
Latest articles about new and trending papers published by Oncotarget

Oncotarget.net: Latest Insights
From Our Authors

Oncotarget.org
Interviews and testimonials from authors who publish with Oncotarget

Volume 3, Issue 2

February 2012

View Archive »

About The Cover

PRL-3 chimeric mAb recognizes EGFP-PRL-3 overexpressed in DLD-1 human colorectal cancer cells by indirect immunofluorescence. Shown is the composite  image of EGFP-PRL-3 in fixed DLD-1 cells (green) and PRL-3 chimeric antibody together with an image of anti-human IgG Texas-Red (red) to reveal the binding to PRL-3 protein. See  Guo et al.

Table of Contents

Editorial Comments

c-MYC and SIRT1 locked in a vicious cycle

c-MYC and SIRT1 locked in a vicious cycle

https://doi.org/10.18632/oncotarget.440

Antje Menssen, and Heiko Hermeking
112-113
Abstract |  PDF |  HTML |  How to cite

Modulating Mesothelin Shedding to Improve Therapy

Modulating Mesothelin Shedding to Improve Therapy

https://doi.org/10.18632/oncotarget.445

Ira Pastan, and Yujian Zhang
114-115
PDF |  HTML |  How to cite

Bryostatin analog: improving on Nature’s design

Bryostatin analog: improving on Nature’s design

https://doi.org/10.18632/oncotarget.460

Dale Boger
116-117
Abstract |  PDF |  HTML |  How to cite

Reviews

Targeting Mnks for Cancer Therapy

Targeting Mnks for Cancer Therapy

https://doi.org/10.18632/oncotarget.453

Jinqiang Hou,Frankie Kam,Christopher G Proud, and Shudong Wang
118-131
Abstract |  PDF |  HTML |  How to cite

Brief Reports

Gain-of-function p53 mutants have widespread genomic locations partially overlapping with p63.

Gain-of-function p53 mutants have widespread genomic locations partially overlapping with p63.

https://doi.org/10.18632/oncotarget.447

Elena Martynova,Silvia Pozzi,Valentina Basile,Diletta Dolfini,Federico Zambelli,Carol Imbriano,Giulio Pavesi, and Roberto Mantovani
132-143
Abstract |  PDF |  HTML |  Supplementary Information |  How to cite

Research Papers

Ras inhibition by FTS attenuates brain tumor growth in mice directly and by enhancing reactivity of cytotoxic lymphocytes

Ras inhibition by FTS attenuates brain tumor growth in mice directly and by enhancing reactivity of cytotoxic lymphocytes

https://doi.org/10.18632/oncotarget.420

Elizabeta Aizman,Adi Mor,Ayelet Levy,Jacob George, and Yoel Kloog
144-157
Abstract |  PDF |  HTML |  How to cite

Engineering the First Chimeric Antibody in Targeting Intracellular PRL-3 Oncoprotein for Cancer Therapy in Mice

Engineering the First Chimeric Antibody in Targeting Intracellular PRL-3 Oncoprotein for Cancer Therapy in Mice

https://doi.org/10.18632/oncotarget.442

Ke Guo,Jing Ping Tang,Jie Li,Cheng Peow Tan,Abdul Qader O. Al-Aidaroos,Cheng William Hong,Leyon Varghese,Zhi Wei Feng,Jung Eun Park,Jian Biao Zhou,Wee Joo Chng, and Qi Zeng
158-171
Abstract |  PDF |  HTML |  Supplementary Information |  How to cite

Single Enantiomer of YK-4-279 Demonstrates Specificity in Targeting the Oncogene EWS-FLI1

Single Enantiomer of YK-4-279 Demonstrates Specificity in Targeting the Oncogene EWS-FLI1

https://doi.org/10.18632/oncotarget.454

Julie S. Barber-Rotenberg,Saravana P. Selvanathan,Yali Kong,Hayriye V. Erkizan,Tara M. Snyder,S. Peter Hong,Christina L. Kobs,Natalie L. South,Steven Summer,Philip J. Monroe,Maksymilian Chruszcz,Veselin Dobrev,Perrer N. Tosso,Lauren J. Scher,Wladek Minor,Milton L. Brown,Steven J. Metallo,Aykut Üren, and Jeffrey A. Toretsky
172-182
Abstract |  PDF |  HTML |  How to cite

Inhibition of p53 expression modifies the specificity of chromatin binding by the androgen receptor

Inhibition of p53 expression modifies the specificity of chromatin binding by the androgen receptor

https://doi.org/10.18632/oncotarget.449

Natalya V. Guseva,Oskar W. Rokhlin,Thomas B. Bair,Rebecca B. Glover, and Michael B. Cohen
183-194
Abstract |  PDF |  HTML |  Supplementary Information |  How to cite

Research Perspectives

MiR-181b: new perspective to evaluate disease progression in chronic lymphocytic leukemia

MiR-181b: new perspective to evaluate disease progression in chronic lymphocytic leukemia

https://doi.org/10.18632/oncotarget.448

Carlo Maria Croce,Rosa Visone,Angelo Veronese, and Veronica Balatti
195-202
Abstract |  PDF |  HTML |  How to cite

Novel targeted therapies for mantle cell lymphoma

Novel targeted therapies for mantle cell lymphoma

https://doi.org/10.18632/oncotarget.426

Lapo Alinari,Beth Christian, and Robert Baiocchi
203-211
Abstract |  PDF |  HTML |  How to cite

Methodological Reports

A Gene Expression Profile Test for the Differential Diagnosis of Ovarian Versus Endometrial Cancers

A Gene Expression Profile Test for the Differential Diagnosis of Ovarian Versus Endometrial Cancers

https://doi.org/10.18632/oncotarget.450

Anita Lal,Rebecca Panos,Mira Marjanovic,Michael Walker,Eloisa Fuentes,Daniel S. Kapp,W David Henner,Ljubomir J. Buturovic, and Meredith Halks-Miller
212-223
Abstract |  PDF |  HTML |  Supplementary Information |  How to cite


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