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Online ISSN: 1949-2553

Oncotarget

Journal Content

Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science.

Its scope is unique. The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases.The term was introduced in the inaugural Editorial,Introducing Oncotarget.

As of January 1, 2022,Oncotarget has shifted to a continuous publishing model. Papers will now be published continuously within yearly volumes in their final and complete form and then quickly released to Pubmed.

Publication Alerts

Subscribe to receive alerts once a paper has been published by Oncotarget.

Oncoscience

Oncoscience Logo

Oncoscience is a peer-reviewed, open-access journal dedicated to cancer research without financial barriers. It is a unique journal that provides FREE publication and access for both authors and readers. Oncoscience is indexed and archived by PubMed and PMC. It is recognized by Impact Journals as a philanthropic endeavor.

SSP 47th Annual Meeting

AACR Annual Meeting 2025

Post-Publication Promotion

Impact Journals, LLC is the publisher of Oncotarget:www.impactjournals.com.

Impact Journals is a member of theWellcome Trust List of Compliant Publishers.

Impact Journals is a member of theSociety for Scholarly Publishing.

On December 23, 2022, Oncotarget server experienced a DDoS attack. As a result, Oncotarget site was inaccessible for a few hours. Oncotarget team swiftly dealt with the situation and took it under control.This malicious action will be reported to the FBI.

Current Volume

Cover for Oncotarget Issue V16N1

This Month's Popular DOIs
(Crossref resolutions)

10.18632/ONCOTARGET.6429
10.18632/ONCOTARGET.5435
10.18632/ONCOTARGET.19087
10.18632/ONCOTARGET.9859
10.18632/ONCOTARGET.23208

Most popular Oncotarget DOIs, measured by the number of times each DOI was successfully resolved.

Most Popular DOIs Published in 2024
(Crossref Data)

Targeting WNT5B and WNT10B in osteosarcoma
10.18632/ONCOTARGET.28617
Next-generation vaccines are showing promise against glioblastoma
10.18632/ONCOTARGET.28636
The gut barrier as a gatekeeper in colorectal cancer treatment
10.18632/ONCOTARGET.28634
Regorafenib synergizes with TAS102 against multiple gastrointestinal cancers and overcomes cancer stemness, trifluridine-induced angiogenesis, ERK1/2 and STAT3 signaling regardless of KRAS or BRAF mutational status
10.18632/ONCOTARGET.28602

Most Popular DOIs of 2024
(Crossref Data)

High infiltration of CD68+ macrophages is associated with poor prognoses of head and neck squamous cell carcinoma patients and is influenced by human papillomavirus
10.18632/ONCOTARGET.24306
Biological effects and epidemiological consequences of arsenic exposure, and reagents that can ameliorate arsenic damagein vivo
10.18632/ONCOTARGET.17745
Model driven optimization of antiangiogenics + cytotoxics combination: application to breast cancer mice treated with bevacizumab + paclitaxel doublet leads to reduced tumor growth and fewer metastasis
10.18632/ONCOTARGET.15484
Generation of V α13/β21+T cell specific target CML cells by TCR gene transfer
10.18632/ONCOTARGET.12441
Association of high microvessel αvβ3 and low PTEN with poor outcome in stage 3 neuroblastoma: rationale for using first in class dual PI3K/BRD4 inhibitor, SF1126
10.18632/ONCOTARGET.13386
FAM83D associates with high tumor recurrence after liver transplantation involving expansion of CD44+ carcinoma stem cells
10.18632/ONCOTARGET.12715
Genetic disruption of calpain-1 and calpain-2 attenuates tumorigenesis in mouse models of HER2+ breast cancer and sensitizes cancer cells to doxorubicin and lapatinib
10.18632/ONCOTARGET.26078

Milestones in Modern Scholarly Publishing

On August 25, 2022, the Office of Science and Technology Policy announced a new government policy legislating the immediate public release of all United States-funded research publications by 2025.Learn more here.

On May 23, 2023, the Council of the European Union adopted conclusions on high-quality, transparent, open, trustworthy, and equitable scholarly publishing. The Council calls for immediate and unrestricted open access to publishing research involving public funds.Learn more.

Oncotarget.org: Blog Posts on
New & Trending Papers

Oncotarget.org
Latest articles about new and trending papers published by Oncotarget

Oncotarget.net: Latest Insights
From Our Authors

Oncotarget.org
Interviews and testimonials from authors who publish with Oncotarget

June 25, 2019

View Archive »

About The Cover

The cover for issue 41 of Oncotarget features Figure 1, "Patient enrolment by region," byMalik, et al.

Table of Contents

Editorial

Transmissible ER stress shapes the leukemic microenvironment

Transmissible ER stress shapes the leukemic microenvironment

https://doi.org/10.18632/oncotarget.27012

John T. Butler, and Peter Kurre
4080-4082
PDF |  How to cite

Research Papers

Palmitate up-regulates laminin expression via ROS/integrin αvβ3 pathway in HLSECs

Palmitate up-regulates laminin expression via ROS/integrin αvβ3 pathway in HLSECs

https://doi.org/10.18632/oncotarget.26937

Qi Zhang,Luxia Jiang,Jing Yu,Limin Tian,Tiankang Guo,Baoshan Di,Jinxing Quan,Jing Feng, and Jing Liu
4083-4090
Abstract |  PDF |  Full Text |  How to cite

The heterogeneity and complexity ofCannabis extracts as antitumor agents

The heterogeneity and complexity ofCannabis extracts as antitumor agents

https://doi.org/10.18632/oncotarget.26983

Liran Baram,Ella Peled,Paula Berman,Ben Yellin,Elazar Besser,Maya Benami,Igal Louria-Hayon,Gil M. Lewitus, and David Meiri
4091-4106
Abstract |  PDF |  Full Text |  Supplementary Information |  How to cite

GPCR-mediated PI3K pathway mutations in pediatric and adult thyroid cancer

GPCR-mediated PI3K pathway mutations in pediatric and adult thyroid cancer

https://doi.org/10.18632/oncotarget.26993

Avaniyapuram Kannan Murugan,Ebtesam Qasem,Hindi Al-Hindi, and Ali S. Alzahrani
4107-4124
Abstract |  PDF |  Full Text |  How to cite

Transcriptional suppression of the miR-15/16 family by c-Myc in malignant pleural mesothelioma

Transcriptional suppression of the miR-15/16 family by c-Myc in malignant pleural mesothelioma

https://doi.org/10.18632/oncotarget.27010

Marissa Williams,Yuen Yee Cheng,Michaela B. Kirschner,Kadir H. Sarun,Karin Schelch,Patrick Winata,Brian McCaughan,Steven Kao,Nico Van Zandwijk, and Glen Reid
4125-4138
Abstract |  PDF |  Full Text |  Supplementary Information |  How to cite

Genomic characterization of early-stage esophageal squamous cell carcinoma in a Japanese population

Genomic characterization of early-stage esophageal squamous cell carcinoma in a Japanese population

https://doi.org/10.18632/oncotarget.27014

Yuji Urabe,Kenichi Kagemoto,C. Nelson Hayes,Koki Nakamura,Kazuhiko Masuda,Atsushi Ono,Shinji Tanaka,Koji Arihiro, and Kazuaki Chayama
4139-4148
Abstract |  PDF |  Full Text |  Supplementary Information |  How to cite

Prostate-specific membrane antigen expression in hepatocellular carcinoma: potential use for prognosis and diagnostic imaging

Prostate-specific membrane antigen expression in hepatocellular carcinoma: potential use for prognosis and diagnostic imaging

https://doi.org/10.18632/oncotarget.27024

Yuri Tolkach,Diane Goltz,Anika Kremer,Hojjat Ahmadzadehfar,Dominik Bergheim,Markus Essler,Marnix Lam,Bart de Keizer,Hans-Peter Fischer, and Glen Kristiansen
4149-4160
Abstract |  PDF |  Full Text |  Supplementary Information |  How to cite

Real-world experience with cabazitaxel in patients with metastatic castration-resistant prostate cancer: a final, pooled analysis of the compassionate use programme and early access programme

Real-world experience with cabazitaxel in patients with metastatic castration-resistant prostate cancer: a final, pooled analysis of the compassionate use programme and early access programme

https://doi.org/10.18632/oncotarget.27031

Zafar Malik,Axel Heidenreich,Sergio Bracarda,Alexandros Ardavanis,Philip Parente,Hans-Joerg Scholz,Ayse Ozatilgan,Evelyne Ecstein-Fraisse,Simon Hitier, and Giuseppe Di Lorenzo
4161-4168
Abstract |  PDF |  Full Text |  How to cite

SPARC gene deletion protects against toxic liver injury and is associated to an enhanced proliferative capacity and reduced oxidative stress response

SPARC gene deletion protects against toxic liver injury and is associated to an enhanced proliferative capacity and reduced oxidative stress response

https://doi.org/10.18632/oncotarget.9456

Estanislao Peixoto,Catalina Atorrasagasti,Mariana Malvicini,Esteban Fiore,Marcelo Rodriguez,Mariana Garcia,Paola Finocchieto,Juan J. Poderoso,Fernando Corrales, and Guillermo Mazzolini
4169-4179
Abstract |  PDF |  Full Text |  Supplementary Information |  How to cite

Cryoablation inhibition of distant untreated tumors (abscopal effect) is immune mediated

Cryoablation inhibition of distant untreated tumors (abscopal effect) is immune mediated

https://doi.org/10.18632/oncotarget.24105

Xueling Yang,Yongfei Guo,Zhi Guo,Tongguo Si,Wenge Xing,Wenwen Yu, and Yan Wang
4180-4191
Abstract |  PDF |  Full Text |  How to cite

MicroRNA-873 inhibits colorectal cancer metastasis by targeting ELK1 and STRN4

MicroRNA-873 inhibits colorectal cancer metastasis by targeting ELK1 and STRN4

https://doi.org/10.18632/oncotarget.24115

Chuannan Fan,Biyu Lin,Zhengjie Huang,Dan Cui,Minyi Zhu,Zhenling Ma,Yunda Zhang,Fan Liu, and Yingfu Liu
4192-4204
Abstract |  PDF |  Full Text |  Supplementary Information |  How to cite

Meta-Analysis

Risk of venous and arterial thromboembolic events associated with tyrosine kinase inhibitors in advanced thyroid cancer: a meta-analysis and systematic review

Risk of venous and arterial thromboembolic events associated with tyrosine kinase inhibitors in advanced thyroid cancer: a meta-analysis and systematic review

https://doi.org/10.18632/oncotarget.24599

Yang Bai,Jing-Yan Li,Jie Li,Bo Zhang,Yong-Hong Liu,Bu-Yong Zhang, and Jian Jing
4205-4212
Abstract |  PDF |  Full Text |  How to cite

Clinical Research Papers

Detecting predictive androgen receptor modifications in circulating prostate cancer cells

Detecting predictive androgen receptor modifications in circulating prostate cancer cells

https://doi.org/10.18632/oncotarget.3925

Julie Steinestel,Manuel Luedeke,Annette Arndt,Thomas J. Schnoeller,Jochen K. Lennerz,Carina Wurm,Christiane Maier,Marcus V. Cronauer,Konrad Steinestel, and Andres J. Schrader
4213-4223
Abstract |  PDF |  Full Text |  Supplementary Information |  How to cite

Reviews

Constructing personalized longitudinal holo’omes of colon cancer-prone humans and their modeling in flies and mice

Constructing personalized longitudinal holo’omes of colon cancer-prone humans and their modeling in flies and mice

https://doi.org/10.18632/oncotarget.6463

Myrofora Panagi,Konstantina Georgila,Aristides G. Eliopoulos, and Yiorgos Apidianakis
4224-4246
Abstract |  PDF |  Full Text |  How to cite

Corrections

Erratum: CRIPTO overexpression promotes mesenchymal differentiation in prostate carcinoma cells through parallel regulation of AKT and FGFR activities

Erratum: CRIPTO overexpression promotes mesenchymal differentiation in prostate carcinoma cells through parallel regulation of AKT and FGFR activities

https://doi.org/10.18632/oncotarget.27038

Stéphane Terry,Ihsan Y. El-Sayed,Damien Destouches,Pascale Maillé,Nathalie Nicolaiew,Guillaume Ploussard,Fannie Semprez,Cynthia Pimpie,Himisha Beltran,Arturo Londono-Vallejo,Yves Allory,Alexandre de la Taille,David S. Salomon, and Francis Vacherot
4247-4248
Correction |  PDF |  How to cite

Correction: Intracellular STING inactivation sensitizes breast cancer cells to genotoxic agents

Correction: Intracellular STING inactivation sensitizes breast cancer cells to genotoxic agents

https://doi.org/10.18632/oncotarget.27042

Julie Gaston,Laura Cheradame,Vanessa Yvonnet,Olivier Deas,Marie-France Poupon,Jean-Gabriel Judde,Stefano Cairo, and Vincent Goffin
4249-4251
Correction |  PDF |  How to cite

Retraction

Retraction: Activation of endoplasmic reticulum stress promotes autophagy and apoptosis and reverses chemoresistance of human small cell lung cancer cells by inhibiting the PI3K/AKT/mTOR signaling pathway

Retraction: Activation of endoplasmic reticulum stress promotes autophagy and apoptosis and reverses chemoresistance of human small cell lung cancer cells by inhibiting the PI3K/AKT/mTOR signaling pathway

https://doi.org/10.18632/oncotarget.27064

Xin-Shuang Yu,Juan Du,Yu-Jun Fan,Feng-Jun Liu,Li-Li Cao,Ning Liang,De-Guo Xu, and Jian-Dong Zhang
4252-4252
Retraction |  PDF |  How to cite


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