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Online ISSN: 1949-2553

Oncotarget

Journal Content

Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science.

Its scope is unique. The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases.The term was introduced in the inaugural Editorial,Introducing Oncotarget.

As of January 1, 2022,Oncotarget has shifted to a continuous publishing model. Papers will now be published continuously within yearly volumes in their final and complete form and then quickly released to Pubmed.

Publication Alerts

Subscribe to receive alerts once a paper has been published by Oncotarget.

Oncoscience

Oncoscience Logo

Oncoscience is a peer-reviewed, open-access journal dedicated to cancer research without financial barriers. It is a unique journal that provides FREE publication and access for both authors and readers. Oncoscience is indexed and archived by PubMed and PMC. It is recognized by Impact Journals as a philanthropic endeavor.

SSP 47th Annual Meeting

AACR Annual Meeting 2025

Post-Publication Promotion

Impact Journals, LLC is the publisher of Oncotarget:www.impactjournals.com.

Impact Journals is a member of theWellcome Trust List of Compliant Publishers.

Impact Journals is a member of theSociety for Scholarly Publishing.

On December 23, 2022, Oncotarget server experienced a DDoS attack. As a result, Oncotarget site was inaccessible for a few hours. Oncotarget team swiftly dealt with the situation and took it under control.This malicious action will be reported to the FBI.

Current Volume

Cover for Oncotarget Issue V16N1

This Month's Popular DOIs
(Crossref resolutions)

10.18632/ONCOTARGET.6429
10.18632/ONCOTARGET.5435
10.18632/ONCOTARGET.19087
10.18632/ONCOTARGET.9859
10.18632/ONCOTARGET.23208

Most popular Oncotarget DOIs, measured by the number of times each DOI was successfully resolved.

Most Popular DOIs Published in 2024
(Crossref Data)

Targeting WNT5B and WNT10B in osteosarcoma
10.18632/ONCOTARGET.28617
Next-generation vaccines are showing promise against glioblastoma
10.18632/ONCOTARGET.28636
The gut barrier as a gatekeeper in colorectal cancer treatment
10.18632/ONCOTARGET.28634
Regorafenib synergizes with TAS102 against multiple gastrointestinal cancers and overcomes cancer stemness, trifluridine-induced angiogenesis, ERK1/2 and STAT3 signaling regardless of KRAS or BRAF mutational status
10.18632/ONCOTARGET.28602

Most Popular DOIs of 2024
(Crossref Data)

High infiltration of CD68+ macrophages is associated with poor prognoses of head and neck squamous cell carcinoma patients and is influenced by human papillomavirus
10.18632/ONCOTARGET.24306
Biological effects and epidemiological consequences of arsenic exposure, and reagents that can ameliorate arsenic damagein vivo
10.18632/ONCOTARGET.17745
Model driven optimization of antiangiogenics + cytotoxics combination: application to breast cancer mice treated with bevacizumab + paclitaxel doublet leads to reduced tumor growth and fewer metastasis
10.18632/ONCOTARGET.15484
Generation of V α13/β21+T cell specific target CML cells by TCR gene transfer
10.18632/ONCOTARGET.12441
Association of high microvessel αvβ3 and low PTEN with poor outcome in stage 3 neuroblastoma: rationale for using first in class dual PI3K/BRD4 inhibitor, SF1126
10.18632/ONCOTARGET.13386
FAM83D associates with high tumor recurrence after liver transplantation involving expansion of CD44+ carcinoma stem cells
10.18632/ONCOTARGET.12715
Genetic disruption of calpain-1 and calpain-2 attenuates tumorigenesis in mouse models of HER2+ breast cancer and sensitizes cancer cells to doxorubicin and lapatinib
10.18632/ONCOTARGET.26078

Milestones in Modern Scholarly Publishing

On August 25, 2022, the Office of Science and Technology Policy announced a new government policy legislating the immediate public release of all United States-funded research publications by 2025.Learn more here.

On May 23, 2023, the Council of the European Union adopted conclusions on high-quality, transparent, open, trustworthy, and equitable scholarly publishing. The Council calls for immediate and unrestricted open access to publishing research involving public funds.Learn more.

Oncotarget.org: Blog Posts on
New & Trending Papers

Oncotarget.org
Latest articles about new and trending papers published by Oncotarget

Oncotarget.net: Latest Insights
From Our Authors

Oncotarget.org
Interviews and testimonials from authors who publish with Oncotarget

June 4, 2019

View Archive »

About The Cover

The cover for issue 38 of Oncotarget features Figure 6, "A model summarizing the role of RNA modification genes in melanoma growth and development," byMalvi, et al.

Table of Contents

Editorial

Cyr61/CCN1 targets for chemosensitization in pancreatic cancer

Cyr61/CCN1 targets for chemosensitization in pancreatic cancer

https://doi.org/10.18632/oncotarget.26986

Snigdha Banerjee,Arnab Ghosh,Daniel D. VonHoff, and Sushanta K. Banerjee
3579-3580
PDF |  How to cite

Priority Research Papers

Elevated telomere dysfunction in cells containing the African-centric Pro47Ser cancer-risk variant of TP53

Elevated telomere dysfunction in cells containing the African-centric Pro47Ser cancer-risk variant of TP53

https://doi.org/10.18632/oncotarget.26980

Stephen Tutton,Zhong Deng,Nitish Gulve,Olga Vladimirova,Kate Beishline,Andreas Wiedmer,Maureen Murphy, and Paul M. Lieberman
3581-3591
Abstract |  PDF |  Full Text |  How to cite

Research Papers

Flow based single cell analysis of the immune landscape distinguishes Barrett’s esophagus from adjacent normal tissue

Flow based single cell analysis of the immune landscape distinguishes Barrett’s esophagus from adjacent normal tissue

https://doi.org/10.18632/oncotarget.26911

Moen Sen,Friedrich Hahn,Taylor A. Black,Maureen DeMarshall,Warren Porter,Eileen Snowden,Stephanie S. Yee,Frances Tong,Mitchell Ferguson,Emylee N. Fleshman,Hiroshi Nakagawa,Gary W. Falk,Gregory G. Ginsberg,Michael L. Kochman,Rainer Blaesius,Anil K. Rustgi, and Erica L. Carpenter
3592-3604
Abstract |  PDF |  Full Text |  Supplementary Information |  How to cite

Prognostic significance of the pretreatment prognostic nutritional index in patients with epithelial ovarian cancer

Prognostic significance of the pretreatment prognostic nutritional index in patients with epithelial ovarian cancer

https://doi.org/10.18632/oncotarget.26914

Naoko Komura,Seiji Mabuchi,Eriko Yokoi,Kotaro Shimura,Mahiru Kawano,Yuri Matsumoto, and Tadashi Kimura
3605-3613
Abstract |  PDF |  Full Text |  Supplementary Information |  How to cite

Molecular characterization of carcinosarcomas arising in the uterus and ovaries

Molecular characterization of carcinosarcomas arising in the uterus and ovaries

https://doi.org/10.18632/oncotarget.26942

Marta Brunetti,Antonio Agostini,Julie Staurseth,Ben Davidson,Sverre Heim, and Francesca Micci
3614-3624
Abstract |  PDF |  Full Text |  How to cite

A three-step approach identifies novel shear stress-sensitive endothelial microRNAs involved in vasculoprotective effects of high-intensity interval training (HIIT)

A three-step approach identifies novel shear stress-sensitive endothelial microRNAs involved in vasculoprotective effects of high-intensity interval training (HIIT)

https://doi.org/10.18632/oncotarget.26944

Boris Schmitz,Franziska L. Breulmann,Bothaynah Jubran,Florian Rolfes,Lothar Thorwesten,Michael Krüger,Andreas Klose,Hans-Joachim Schnittler, and Stefan-Martin Brand
3625-3640
Abstract |  PDF |  Full Text |  Supplementary Information |  How to cite

Deep sequencing of a recurrent oligodendroglioma and the derived xenografts reveals new insights into the evolution of human oligodendroglioma and candidate driver genes

Deep sequencing of a recurrent oligodendroglioma and the derived xenografts reveals new insights into the evolution of human oligodendroglioma and candidate driver genes

https://doi.org/10.18632/oncotarget.26950

Nadin D. Exner,Jaime Alberto Campos Valenzuela,Khalil Abou-El-Ardat,Hrvoje Miletic,Peter C. Huszthy,Petra M. Radehaus,Evelin Schröck,Rolf Bjerkvig,Lars Kaderali,Barbara Klink, and Janice M. Nigro
3641-3653
Abstract |  PDF |  Full Text |  Supplementary Information |  How to cite

Development, validation, and comparison of gene analysis methods for detectingEGFR mutation from non-small cell lung cancer patients-derived circulating free DNA

Development, validation, and comparison of gene analysis methods for detectingEGFR mutation from non-small cell lung cancer patients-derived circulating free DNA

https://doi.org/10.18632/oncotarget.26951

Masaki Hanibuchi,Akira Kanoh,Takuya Kuramoto,Tatsuro Saito,Makoto Tobiume,Atsuro Saijo,Hiroyuki Kozai,Mayo Kondo,Shun Morizumi,Hiroto Yoneda,Kozo Kagawa,Hirokazu Ogino,Seidai Sato,Hiroshi Kawano,Kenji Otsuka,Yuko Toyoda,Hiroshi Nokihara,Hisatsugu Goto, and Yasuhiko Nishioka
3654-3666
Abstract |  PDF |  Full Text |  Supplementary Information |  How to cite

PI3K inhibition enhances the anti-tumor effect of eribulin in triple negative breast cancer

PI3K inhibition enhances the anti-tumor effect of eribulin in triple negative breast cancer

https://doi.org/10.18632/oncotarget.26960

Sandeep Rajput,Zhanfang Guo,Shunqiang Li, and Cynthia X. Ma
3667-3680
Abstract |  PDF |  Full Text |  Supplementary Information |  How to cite

Evaluation of 6-mercaptopurine in a cell culture model of adaptable triple-negative breast cancer with metastatic potential

Evaluation of 6-mercaptopurine in a cell culture model of adaptable triple-negative breast cancer with metastatic potential

https://doi.org/10.18632/oncotarget.26978

Balraj Singh,Vanessa N. Sarli,Hannah E. Kinne,Anna Shamsnia, and Anthony Lucci
3681-3693
Abstract |  PDF |  Full Text |  Supplementary Information |  How to cite

Cancer-testis antigens MAGEA proteins are incorporated into extracellular vesicles released by cells

Cancer-testis antigens MAGEA proteins are incorporated into extracellular vesicles released by cells

https://doi.org/10.18632/oncotarget.26979

Anneli Kuldkepp,Magda Karakai,Eve Toomsoo,Olavi Reinsalu, and Reet Kurg
3694-3708
Abstract |  PDF |  Full Text |  How to cite

Functional interplay between YY1 and CARM1 promotes oral carcinogenesis

Functional interplay between YY1 and CARM1 promotes oral carcinogenesis

https://doi.org/10.18632/oncotarget.26984

Amit K. Behera,Manoj Kumar,Muthu K. Shanmugam,Aditya Bhattacharya,Vinay J. Rao,Akshay Bhat,Madavan Vasudevan,Kodaganur S. Gopinath,Azeem Mohiyuddin,Anupam Chatterjee,Gautam Sethi, and Tapas K. Kundu
3709-3724
Abstract |  PDF |  Full Text |  Supplementary Information |  How to cite

1,4-dihydroxy quininib attenuates growth of colorectal cancer cells and xenografts and regulates the TIE-2 signaling pathway in patient tumours

1,4-dihydroxy quininib attenuates growth of colorectal cancer cells and xenografts and regulates the TIE-2 signaling pathway in patient tumours

https://doi.org/10.18632/oncotarget.26966

Clare T. Butler,Susan A. Kennedy,Amy Buckley,Ronan Doyle,Emer Conroy,William M. Gallagher,Jacintha O’Sullivan, and Breandán N. Kennedy
3725-3744
Abstract |  PDF |  Full Text |  How to cite

Dissecting the role of RNA modification regulatory proteins in melanoma

Dissecting the role of RNA modification regulatory proteins in melanoma

https://doi.org/10.18632/oncotarget.26959

Parmanand Malvi,Biao Wang,Shreni Shah, and Romi Gupta
3745-3759
Abstract |  PDF |  Full Text |  Supplementary Information |  How to cite |  Podcast
Special Collection ToC

Comparing progression molecular mechanisms between lung adenocarcinoma and lung squamous cell carcinoma based on genetic and epigenetic networks: big data mining and genome-wide systems identification

Comparing progression molecular mechanisms between lung adenocarcinoma and lung squamous cell carcinoma based on genetic and epigenetic networks: big data mining and genome-wide systems identification

https://doi.org/10.18632/oncotarget.26940

Shan-Ju Yeh,Chien-An Chang,Cheng-Wei Li,Lily Hui-Ching Wang, and Bor-Sen Chen
3760-3806
Abstract |  PDF |  Full Text |  Supplementary Information |  How to cite

Association study of apelin-APJ system genetic polymorphisms with incident metabolic syndrome in a Chinese population: a case-control study

Association study of apelin-APJ system genetic polymorphisms with incident metabolic syndrome in a Chinese population: a case-control study

https://doi.org/10.18632/oncotarget.24111

Meijin Zhang,Feng Peng,Liming Lin,Mingzhong Yu,Chengyuan Huang,Dan Hu,Qinghui Guo,Changsheng Xu, and Jinxiu Lin
3807-3817
Abstract |  PDF |  Full Text |  Supplementary Information |  How to cite

Case Reports

Regression ofBRAFV600E mutant adult glioblastoma after primary combined BRAF-MEK inhibitor targeted therapy: a report of two cases

Regression ofBRAFV600E mutant adult glioblastoma after primary combined BRAF-MEK inhibitor targeted therapy: a report of two cases

https://doi.org/10.18632/oncotarget.26932

Peter Y.M. Woo,Tai-Chung Lam,Jenny K.S. Pu,Lai-Fung Li,Roland C.Y. Leung,Jason M.K. Ho,James T.F. Zhung,Belinda Wong,Timonthy S.K. Chan,Herbert H.F. Loong, and Ho-Keung Ng
3818-3826
Abstract |  PDF |  Full Text |  How to cite

Corrections

Correction: First-in-human phase 1 study of the BTK inhibitor GDC-0853 in relapsed or refractory B-cell NHL and CLL

Correction: First-in-human phase 1 study of the BTK inhibitor GDC-0853 in relapsed or refractory B-cell NHL and CLL

https://doi.org/10.18632/oncotarget.27011

John C. Byrd,Stephen Smith,Nina Wagner-Johnston,Jeff Sharman,Andy I. Chen,Ranjana Advani,Bradley Augustson,Paula Marlton,S. Renee Commerford,Kwame Okrah,Lichuan Liu,Elaine Murray,Elicia Penuel,Ashley F. Ward, and Ian W. Flinn
3827-3830
Correction |  PDF |  How to cite


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