
Much of the work carried out by DTT is in support of the National Toxicology Program (NTP), an interagency partnership of the Food and Drug Administration, National Institute for Occupational Safety and Health, and NIEHS.

Sonika Patial is a Scientist / Pathologist in the Comparative and Molecular Pathogenesis Branch (CMPB) in the Division of Translational Toxicology (DTT) at the National Institute of Environmental Health Sciences (NIEHS). Additionally, she is an adjunct Associate Professor in the Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University.
Dr. Patial received her Doctor of Veterinary Medicine degree from The College of Veterinary and Animal Sciences, Palampur, India (2003); her Master of Veterinary Science in Animal Biotechnology from Indian Veterinary Research Institute, Izatnagar, India (2005); and her PhD from Michigan State University, East Lansing (2010). She completed her Veterinary Anatomic Pathology residency training from Louisiana State University, Baton Rouge (2016). Dr. Patial is a diplomate of the American College of Veterinary Pathologists.
Before joining DTT, Dr. Patial was a tenure-track Assistant Professor in the Department of Comparative Biomedical Sciences in the LSU School of Veterinary Medicine (2017-2022), where she established an independent research program focused on investigating the molecular mechanisms underlying environmentally induced inflammatory diseases of the lung. During her tenure, she secured significant research funding, including an R01 grant, and received several accolades, such as the ASIP Early Career Investigator Award, the Lung COBRE Investigator Award, multiple placements on the Dean’s Teacher Merit Honor Roll, and the LSU Alumni Association Rising Faculty Research Award. Dr. Patial's contributions to the field include multiple peer-reviewed publications, teaching and mentoring, and invited talks, demonstrating her expertise in both research and training the next generation of scientists. Her current research interests center on understanding the molecular pathology of occupational and environmentally induced pathologies particularly the impact of environment on chemical exposures and their contribution to respiratory health and chronic respiratory diseases.
Recent Publications
- Lamichhane R, Choudhary I, Singamsetty D, Patial S, Saini Y. Tristetraprolin protects against ozone-induced acute lung injury and inflammation in mice.Journal of immunology (Baltimore, Md. : 1950). 2026 Jan 21;215(1):. [ AbstractLamichhane R, Choudhary I, Singamsetty D, Patial S, Saini Y. Tristetraprolin protects against ozone-induced acute lung injury and inflammation in mice. Journal of immunology (Baltimore, Md. : 1950). 2026 Jan 21]
- Mao Y, Patial S, Saini Y. Myeloid cell-specific HMGB1 deficiency exaggerates mucoinflammatory responses but promotes bacterial clearance in mucoinflammatory lung disease.Scientific reports. 2026 Jan 12;16(1):3391. [ AbstractMao Y, Patial S, Saini Y. Myeloid cell-specific HMGB1 deficiency exaggerates mucoinflammatory responses but promotes bacterial clearance in mucoinflammatory lung disease. Scientific reports. 2026 Jan 12]
- Vo T, Choudhary I, Patial S, Saini Y. Single-cell transcriptomics reveal alveolar macrophages-specific responses in single-hit ozone exposure model in mice.American journal of physiology. Lung cellular and molecular physiology. 2026 Jan 02 [Epub ahead of print]. [ AbstractVo T, Choudhary I, Patial S, Saini Y. Single-cell transcriptomics reveal alveolar macrophages-specific responses in single-hit ozone exposure model in mice. American journal of physiology. Lung cellular and molecular physiology. 2026 Jan 02]
- Vo T, Patial S, Saini Y. Repetitive ozone exposure worsens features of muco-inflammatory disease in developedScnn1b-Tg+ mice lungs.Frontiers in toxicology. 2025;7:1540468. [ AbstractVo T, Patial S, Saini Y. Repetitive ozone exposure worsens features of muco-inflammatory disease in developedScnn1b-Tg+ mice lungs. Frontiers in toxicology. 2025]
- Paudel K, Patial S, Saini Y. Prior acute ozone injury dampens Th2 responses to subsequent repetitive ozone exposures in mice.Research square. 2025 Dec 09 [Epub ahead of print]. [ AbstractPaudel K, Patial S, Saini Y. Prior acute ozone injury dampens Th2 responses to subsequent repetitive ozone exposures in mice. Research square. 2025 Dec 09]
More Recent Publications from PubMed
- NIEHS News in Brief - Environmental Factor, July 2024
