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Review
.2017 Sep 15;82(6):421-430.
doi: 10.1016/j.biopsych.2017.05.012. Epub 2017 May 25.

Computational Psychosomatics and Computational Psychiatry: Toward a Joint Framework for Differential Diagnosis

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Review

Computational Psychosomatics and Computational Psychiatry: Toward a Joint Framework for Differential Diagnosis

Frederike H Petzschner et al. Biol Psychiatry..
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Abstract

This article outlines how a core concept from theories of homeostasis and cybernetics, the inference-control loop, may be used to guide differential diagnosis in computational psychiatry and computational psychosomatics. In particular, we discuss 1) how conceptualizing perception and action as inference-control loops yields a joint computational perspective on brain-world and brain-body interactions and 2) how the concrete formulation of this loop as a hierarchical Bayesian model points to key computational quantities that inform a taxonomy of potential disease mechanisms. We consider the utility of this perspective for differential diagnosis in concrete clinical applications.

Keywords: Allostasis; Cybernetics; Hierarchical Bayesian model; Homeostasis; Inference; Metacognition; Prediction error.

Copyright © 2017 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

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