Dax1 is required for testis determination
- PMID:12679814
- DOI: 10.1038/ng1141
Dax1 is required for testis determination
Abstract
The orphan nuclear receptor, Dax1, was originally proposed to act as an 'anti-testis' factor. We find, however, that Nr0b1 (also called Dax1 and Ahch, which encodes Dax1) is in fact required for testis differentiation.
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