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Unbearable Pain

MedGen UID:: 768654
•Concept ID:: C3640014
•: Sign or Symptom

Definition

A sensation of extreme discomfort and anguish that is overwhelming and unendurable. [fromNCI]

Term Hierarchy

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVUnbearable Pain

Phenotypic abnormality
- Constitutional symptom
  - Pain
    - Unbearable Pain

Professional guidelines

PubMed

Medical cannabis for chronic pain: can it make a difference in pain management?

Maharajan MK,Yong YJ,Yip HY,Woon SS,Yeap KM,Yap KY,Yip SC,Yap KX
J Anesth2020 Feb;34(1):95-103.Epub 2019 Sep 18doi: 10.1007/s00540-019-02680-y.PMID:31535218

Calciphylaxis: Approach to Diagnosis and Management.

Seethapathy H,Noureddine L
Adv Chronic Kidney Dis2019 Nov;26(6):484-490.doi: 10.1053/j.ackd.2019.09.005.PMID:31831126

Diagnosis and management of spinal infections.

Nagashima H,Tanishima S,Tanida A
J Orthop Sci2018 Jan;23(1):8-13.Epub 2017 Oct 20doi: 10.1016/j.jos.2017.09.016.PMID:29066036

See all (15)

These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See theFAQ for details.

These guidelines are manually curated by the MedGen team to supplement articles available in PubMed. See theFAQ for details.

Recent clinical studies

Etiology

'You have a little human being kicking inside you and an unbearable pain of knowing there will be a void at the end': A meta-ethnography exploring the experience of parents whose baby is diagnosed antenatally with a life limiting or life-threatening condition.

Tatterton MJ,Fisher MJ
Palliat Med2023 Oct;37(9):1289-1302.Epub 2023 May 2doi: 10.1177/02692163231172244.PMID:37129319 Free PMC Article

Constitutive Inflammatory Cytokine Storm: A Major Threat to Human Health.

Gupta KK,Khan MA,Singh SK
J Interferon Cytokine Res2020 Jan;40(1):19-23.Epub 2019 Nov 22doi: 10.1089/jir.2019.0085.PMID:31755797

Diagnosis and management of spinal infections.

Nagashima H,Tanishima S,Tanida A
J Orthop Sci2018 Jan;23(1):8-13.Epub 2017 Oct 20doi: 10.1016/j.jos.2017.09.016.PMID:29066036

Randomized Clinical Trials on Deep Carious Lesions: 5-Year Follow-up.

Bjørndal L,Fransson H,Bruun G,Markvart M,Kjældgaard M,Näsman P,Hedenbjörk-Lager A,Dige I,Thordrup M
J Dent Res2017 Jul;96(7):747-753.Epub 2017 Apr 14doi: 10.1177/0022034517702620.PMID:28410008

Post-piercing perichondritis.

Fernandez AP,Neto IC,Anias CR,Pinto PCL,de Carvalho E Castro J,Carpes AF
Braz J Otorhinolaryngol2008 Nov-Dec;74(6):933-937.doi: 10.1016/S1808-8694(15)30156-7.PMID:19582352 Free PMC Article

See all (123)

Diagnosis

Tatterton MJ,Fisher MJ
Palliat Med2023 Oct;37(9):1289-1302.Epub 2023 May 2doi: 10.1177/02692163231172244.PMID:37129319 Free PMC Article

Calciphylaxis: Approach to Diagnosis and Management.

Seethapathy H,Noureddine L
Adv Chronic Kidney Dis2019 Nov;26(6):484-490.doi: 10.1053/j.ackd.2019.09.005.PMID:31831126

Diagnosis and management of spinal infections.

Nagashima H,Tanishima S,Tanida A
J Orthop Sci2018 Jan;23(1):8-13.Epub 2017 Oct 20doi: 10.1016/j.jos.2017.09.016.PMID:29066036

Post-piercing perichondritis.

Fernandez AP,Neto IC,Anias CR,Pinto PCL,de Carvalho E Castro J,Carpes AF
Braz J Otorhinolaryngol2008 Nov-Dec;74(6):933-937.doi: 10.1016/S1808-8694(15)30156-7.PMID:19582352 Free PMC Article

Sedation-free colonoscopy.

Takahashi Y,Tanaka H,Kinjo M,Sakumoto K
Dis Colon Rectum2005 Apr;48(4):855-9.doi: 10.1007/s10350-004-0860-0.PMID:15768182

See all (68)

Therapy

Exudate Absorbing and Antimicrobial Hydrogel Integrated with Multifunctional Curcumin-Loaded Magnesium Polyphenol Network for Facilitating Burn Wound Healing.

Gong Y,Wang P,Cao R,Wu J,Ji H,Wang M,Hu C,Huang P,Wang X
ACS Nano2023 Nov 28;17(22):22355-22370.Epub 2023 Nov 6doi: 10.1021/acsnano.3c04556.PMID:37930078

Calciphylaxis: Approach to Diagnosis and Management.

Seethapathy H,Noureddine L
Adv Chronic Kidney Dis2019 Nov;26(6):484-490.doi: 10.1053/j.ackd.2019.09.005.PMID:31831126

Randomized Clinical Trials on Deep Carious Lesions: 5-Year Follow-up.

Bjørndal L,Fransson H,Bruun G,Markvart M,Kjældgaard M,Näsman P,Hedenbjörk-Lager A,Dige I,Thordrup M
J Dent Res2017 Jul;96(7):747-753.Epub 2017 Apr 14doi: 10.1177/0022034517702620.PMID:28410008

Photodynamic Therapy: Past, Present and Future.

Chilakamarthi U,Giribabu L
Chem Rec2017 Aug;17(8):775-802.Epub 2017 Jan 2doi: 10.1002/tcr.201600121.PMID:28042681

Post-piercing perichondritis.

Fernandez AP,Neto IC,Anias CR,Pinto PCL,de Carvalho E Castro J,Carpes AF
Braz J Otorhinolaryngol2008 Nov-Dec;74(6):933-937.doi: 10.1016/S1808-8694(15)30156-7.PMID:19582352 Free PMC Article

See all (144)

Prognosis

Rheumatoid Arthritis Has Won the Battle but Not the War: How Many Joints Will We Save Tomorrow?

Oberemok VV,Andreeva O,Laikova K,Alieva E,Temirova Z
Medicina (Kaunas)2023 Oct 18;59(10)doi: 10.3390/medicina59101853.PMID:37893571 Free PMC Article

The Goals of Medicine and Compassion in the Ethical Assessment of Euthanasia and Physician-Assisted Suicide: Relieving Pain and Suffering by Protecting, Promoting, and Maintaining the Person's Well-Being.

Avci E
J Palliat Care2022 Jul;37(3):366-371.Epub 2022 Feb 9doi: 10.1177/08258597221078371.PMID:35138188

Calciphylaxis: Approach to Diagnosis and Management.

Seethapathy H,Noureddine L
Adv Chronic Kidney Dis2019 Nov;26(6):484-490.doi: 10.1053/j.ackd.2019.09.005.PMID:31831126

Diagnosis and management of spinal infections.

Nagashima H,Tanishima S,Tanida A
J Orthop Sci2018 Jan;23(1):8-13.Epub 2017 Oct 20doi: 10.1016/j.jos.2017.09.016.PMID:29066036

Pain and pain generation in pancreatic cancer.

di Mola FF,di Sebastiano P
Langenbecks Arch Surg2008 Nov;393(6):919-22.Epub 2008 Jan 12doi: 10.1007/s00423-007-0277-z.PMID:18193269

See all (38)

Clinical prediction guides

Understanding the psychodynamics of the pathway to suicide.

Gibbons R
Int Rev Psychiatry2024 Jun-Aug;36(4-5):508-516.Epub 2024 May 24doi: 10.1080/09540261.2024.2351937.PMID:39470097

Efficacy and safety of a novel pain management device, AT-04, for endometriosis-related pain: study protocol for a phase III randomized controlled trial.

Ishikawa H,Yoshino O,Taniguchi F,Harada T,Momoeda M,Osuga Y,Hikake T,Hattori Y,Hanawa M,Inaba Y,Hanaoka H,Koga K
Reprod Health2024 Jan 26;21(1):12.doi: 10.1186/s12978-024-01739-8.PMID:38279180 Free PMC Article

Blank pain and pathological mourning in the analytic situation.

Groarke S
Int J Psychoanal2023 Dec;104(6):1006-1024.Epub 2023 Dec 21doi: 10.1080/00207578.2023.2234969.PMID:38127483

Associations between adherence to MIND diet and severity, duration and frequency of migraine headaches among migraine patients.

Askarpour M,Yarizadeh H,Sheikhi A,Khorsha F,Mirzaei K
BMC Res Notes2020 Jul 16;13(1):341.doi: 10.1186/s13104-020-05181-4.PMID:32678009 Free PMC Article

Diagnosis and management of spinal infections.

Nagashima H,Tanishima S,Tanida A
J Orthop Sci2018 Jan;23(1):8-13.Epub 2017 Oct 20doi: 10.1016/j.jos.2017.09.016.PMID:29066036

See all (104)

Recent systematic reviews

Prevalence and causes of self-medication for oral health problems: a systematic review and meta-analysis.

Katebi K,Eslami H,Jabbari S
BMC Oral Health2024 Sep 19;24(1):1115.doi: 10.1186/s12903-024-04900-8.PMID:39300478 Free PMC Article

Safety and efficacy of microwave ablation for benign thyroid nodules and papillary thyroid microcarcinomas: A systematic review and meta-analysis.

Cui T,Jin C,Jiao D,Teng D,Sui G
Eur J Radiol2019 Sep;118:58-64.Epub 2019 Jun 29doi: 10.1016/j.ejrad.2019.06.027.PMID:31439259

Treatment options in painful chronic pancreatitis: a systematic review.

D'Haese JG,Ceyhan GO,Demir IE,Tieftrunk E,Friess H
HPB (Oxford)2014 Jun;16(6):512-21.Epub 2013 Aug 29doi: 10.1111/hpb.12173.PMID:24033614 Free PMC Article

See all (3)

Supplemental Content

Practice guidelines

PubMed
See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See theFAQ for details.