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Slit ventricle syndrome

MedGen UID:: 389221
•Concept ID:: C2316166
•: Disease or Syndrome

Synonyms:	Slit Ventricle Syndrome; Slit Ventricle Syndromes; Syndrome, Slit Ventricle; Syndromes, Slit Ventricle
SNOMED CT:	Slit ventricle syndrome (431468008)

Definition

An intermittent and self-limiting headache disorder in individuals with CEREBROSPINAL FLUID SHUNTS emplaced for the treatment of HYDROCEPHALUS. The symptoms of headache, vomiting, and cranial neuropathies are associated with intermittent obstruction of the shunt. [fromMeSH]

Term Hierarchy

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVSlit ventricle syndrome

Abnormality of prenatal development or birth
- Fetal anomaly
  - Congenital Systemic Disorder
    - Abnormality of the nervous system
      - Abnormal nervous system physiology
        Headache
        Slit ventricle syndrome

Professional guidelines

PubMed

Short-term dexamethasone treatment for symptomatic slit ventricle syndrome.

Steinbok P
Childs Nerv Syst2005 Nov;21(11):985.doi: 10.1007/s00381-004-1133-x.PMID:15933886

The problematic slit ventricle syndrome. A review of the literature and proposed algorithm for treatment.

Olson S
Pediatr Neurosurg2004 Nov-Dec;40(6):264-9.doi: 10.1159/000083738.PMID:15821356

Diagnosis and treatment of the slit ventricle syndrome.

Walker ML,Fried A,Petronio J
Neurosurg Clin N Am1993 Oct;4(4):707-14.PMID:8241791

See all (11)

These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See theFAQ for details.

These guidelines are manually curated by the MedGen team to supplement articles available in PubMed. See theFAQ for details.

Recent clinical studies

Etiology

Positional shunt assist for slit ventricle syndrome.

Azolai L,Constantini S,Constantini L,Roth J
Childs Nerv Syst2024 Jan;40(1):109-114.Epub 2023 Sep 11doi: 10.1007/s00381-023-06145-2.PMID:37695368

Subtemporal Decompression in Resistant Slit Ventricle Syndrome in Children: An Observational Study and Survival Analysis.

Khan M,Craven CL,Tahir MZ
Pediatr Neurosurg2023;58(6):420-428.Epub 2023 Oct 17doi: 10.1159/000534611.PMID:37848014

Kyphectomy and Pedicular Screw Fixation with Posterior-Only Approach in Pediatric Patients with Myelomeningocele.

Kaplan SÇ,Ekşi MŞ,Bayri Y,Toktaş ZO,Konya D
Pediatr Neurosurg2015;50(3):133-44.Epub 2015 Jun 6doi: 10.1159/000430467.PMID:26067202

ETV as a last resort.

Mandiwanza T,Zakaria Z,Khalil A,Crimmins D,Caird J
Childs Nerv Syst2014 May;30(5):859-66.Epub 2013 Nov 30doi: 10.1007/s00381-013-2330-2.PMID:24292271

The problematic slit ventricle syndrome. A review of the literature and proposed algorithm for treatment.

Olson S
Pediatr Neurosurg2004 Nov-Dec;40(6):264-9.doi: 10.1159/000083738.PMID:15821356

See all (77)

Diagnosis

Slit Ventricle Syndrome.

Yan X,Zheng J,Tao X,Ma Y,Qin S
J Craniofac Surg2023 Sep 1;34(6):e566-e568.Epub 2023 May 25doi: 10.1097/SCS.0000000000009400.PMID:37226307

Management of Slit Ventricle Syndrome: A Single-Center Case Series of 32 Surgically Treated Patients.

Auricchio AM,Bohnen A,Nichelatti M,Cenzato M,Talamonti G
World Neurosurg2022 Feb;158:e352-e361.Epub 2021 Nov 6doi: 10.1016/j.wneu.2021.10.183.PMID:34749014

Craniocerebral disproportion: a topical review and proposal toward a new definition, diagnosis, and treatment protocol.

Sandler AL,Goodrich JT,Daniels LB 3rd,Biswas A,Abbott R
Childs Nerv Syst2013 Nov;29(11):1997-2010.Epub 2013 Aug 24doi: 10.1007/s00381-013-2257-7.PMID:23974969

Lumbar peritoneal shunt.

Yadav YR,Parihar V,Sinha M
Neurol India2010 Mar-Apr;58(2):179-84.doi: 10.4103/0028-3886.63778.PMID:20508332

The slit ventricle syndrome.

Bruce DA,Weprin B
Neurosurg Clin N Am2001 Oct;12(4):709-17, viii.PMID:11524292

See all (59)

Therapy

Slit Ventricle Syndrome.

Yan X,Zheng J,Tao X,Ma Y,Qin S
J Craniofac Surg2023 Sep 1;34(6):e566-e568.Epub 2023 May 25doi: 10.1097/SCS.0000000000009400.PMID:37226307

Shunt overdrainage syndrome: review of the literature.

Ros B,Iglesias S,Martín Á,Carrasco A,Ibáñez G,Arráez MA
Neurosurg Rev2018 Oct;41(4):969-981.Epub 2017 Mar 29doi: 10.1007/s10143-017-0849-5.PMID:28352945

Craniocerebral disproportion: a topical review and proposal toward a new definition, diagnosis, and treatment protocol.

Sandler AL,Goodrich JT,Daniels LB 3rd,Biswas A,Abbott R
Childs Nerv Syst2013 Nov;29(11):1997-2010.Epub 2013 Aug 24doi: 10.1007/s00381-013-2257-7.PMID:23974969

Cerebrospinal fluid physiology: problems and possibilities.

Walker ML
Clin Neurosurg2011;58:65-71.doi: 10.1227/neu.0b013e3182270170.PMID:21916129

The slit ventricle syndrome: advances based on technology and understanding.

Rekate HL
Pediatr Neurosurg2004 Nov-Dec;40(6):259-63.doi: 10.1159/000083737.PMID:15821355

See all (69)

Prognosis

Management of Slit Ventricle Syndrome: A Single-Center Case Series of 32 Surgically Treated Patients.

Auricchio AM,Bohnen A,Nichelatti M,Cenzato M,Talamonti G
World Neurosurg2022 Feb;158:e352-e361.Epub 2021 Nov 6doi: 10.1016/j.wneu.2021.10.183.PMID:34749014

The use of noninvasive electromagnetic neuronavigation for slit ventricle syndrome and complex hydrocephalus in a pediatric population.

Clark S,Sangra M,Hayhurst C,Kandasamy J,Jenkinson M,Lee M,Mallucci C
J Neurosurg Pediatr2008 Dec;2(6):430-4.doi: 10.3171/PED.2008.2.12.430.PMID:19035692

The slit ventricle syndrome.

Bruce DA,Weprin B
Neurosurg Clin N Am2001 Oct;12(4):709-17, viii.PMID:11524292

Long-term results after ventriculo-atrial shunting in children.

Vernet O,Campiche R,de Tribolet N
Childs Nerv Syst1995 Mar;11(3):176-9.doi: 10.1007/BF00570261.PMID:7773980

Hydrocephalus: overdrainage by ventricular shunts. A review and recommendations.

Pudenz RH,Foltz EL
Surg Neurol1991 Mar;35(3):200-12.doi: 10.1016/0090-3019(91)90072-h.PMID:1996449

See all (49)

Clinical prediction guides

Subtemporal Decompression in Resistant Slit Ventricle Syndrome in Children: An Observational Study and Survival Analysis.

Khan M,Craven CL,Tahir MZ
Pediatr Neurosurg2023;58(6):420-428.Epub 2023 Oct 17doi: 10.1159/000534611.PMID:37848014

Cranial expansion and aqueductoplasty for combined isolated fourth ventricle and slit-ventricle syndrome: a surgical alternative.

Tirado-Caballero J,Rivero-Garvia M,Moreno-Madueño G,Gómez-González E,Márquez-Rivas J
Childs Nerv Syst2021 Mar;37(3):885-894.Epub 2020 Oct 25doi: 10.1007/s00381-020-04939-2.PMID:33099694

Development of brain ventricular system.

Korzh V
Cell Mol Life Sci2018 Feb;75(3):375-383.Epub 2017 Aug 5doi: 10.1007/s00018-017-2605-y.PMID:28780589 Free PMC Article

Shunt Testing In Vivo: Observational Study of Problems with Ventricular Catheter.

Czosnyka ZH,Sinha R,Morgan JA,Wawrzynski JR,Price SJ,Garnett M,Pickard JD,Czosnyka M
Acta Neurochir Suppl2016;122:353-6.doi: 10.1007/978-3-319-22533-3_69.PMID:27165935

The slit ventricle syndrome: advances based on technology and understanding.

Rekate HL
Pediatr Neurosurg2004 Nov-Dec;40(6):259-63.doi: 10.1159/000083737.PMID:15821355

See all (23)

Supplemental Content

Practice guidelines

PubMed
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Bookshelf
See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See theFAQ for details.