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Sciatica

MedGen UID:
19893
•Concept ID:
C0036396
•
Sign or Symptom
Synonyms:Neuralgia, Sciatic; Neuralgias, Sciatic; Sciatic Neuralgia; Sciatic Neuralgias
SNOMED CT:Sciatica neuralgia (23056005); Sciatica (23056005); Neuralgia-neuritis of sciatic nerve (23056005); Sciatic neuralgia (23056005)
 
HPO:HP:0011868
Monarch Initiative:MONDO:0024333

Definition

Pain in the lower back and hip radiating in the distribution of the sciatic nerve. [fromHPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSciatica

Professional guidelines

PubMed

Zaina F,Côté P,Cancelliere C,Di Felice F,Donzelli S,Rauch A,Verville L,Negrini S,Nordin M
Arch Phys Med Rehabil2023 Nov;104(11):1913-1927.Epub 2023 Mar 23doi: 10.1016/j.apmr.2023.02.022.PMID:36963709
Jensen RK,Kongsted A,Kjaer P,Koes B
BMJ2019 Nov 19;367:l6273.doi: 10.1136/bmj.l6273.PMID:31744805
Koes BW,van Tulder MW,Peul WC
BMJ2007 Jun 23;334(7607):1313-7.doi: 10.1136/bmj.39223.428495.BE.PMID:17585160Free PMC Article

Curated

UK NICE Guideline NG59, Low back pain and sciatica in over 16s: assessment and management, 2020

These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See theFAQ for details.
These guidelines are manually curated by the MedGen team to supplement articles available in PubMed. See theFAQ for details.

Recent clinical studies

Etiology

Dove L,Jones G,Kelsey LA,Cairns MC,Schmid AB
Eur Spine J2023 Feb;32(2):517-533.Epub 2022 Dec 29doi: 10.1007/s00586-022-07356-y.PMID:36580149Free PMC Article
Bastos RM,Moya CR,de Vasconcelos RA,Costa LOP
J Man Manip Ther2022 Aug;30(4):207-227.Epub 2022 Jan 24doi: 10.1080/10669817.2021.2024677.PMID:35067217Free PMC Article
Parreira P,Maher CG,Steffens D,Hancock MJ,Ferreira ML
Spine J2018 Sep;18(9):1715-1721.Epub 2018 May 21doi: 10.1016/j.spinee.2018.05.018.PMID:29792997
Mooney V,Robertson J
Clin Orthop Relat Res1976 Mar-Apr;(115):149-56.PMID:130216
Smith L
Clin Orthop Relat Res1969 Nov-Dec;67:72-80.PMID:4243384

Diagnosis

Jensen RK,Kongsted A,Kjaer P,Koes B
BMJ2019 Nov 19;367:l6273.doi: 10.1136/bmj.l6273.PMID:31744805
Deyo RA,Mirza SK
N Engl J Med2016 May 5;374(18):1763-72.doi: 10.1056/NEJMcp1512658.PMID:27144851
Ropper AH,Zafonte RD
N Engl J Med2015 Mar 26;372(13):1240-8.doi: 10.1056/NEJMra1410151.PMID:25806916
Kirschner JS,Foye PM,Cole JL
Muscle Nerve2009 Jul;40(1):10-8.doi: 10.1002/mus.21318.PMID:19466717
Koes BW,van Tulder MW,Peul WC
BMJ2007 Jun 23;334(7607):1313-7.doi: 10.1136/bmj.39223.428495.BE.PMID:17585160Free PMC Article

Therapy

Danazumi MS,Bello B,Yakasai AM,Kaka B
J Osteopath Med2021 Feb 26;121(4):391-400.doi: 10.1515/jom-2020-0261.PMID:33705612
Rubinstein SM,de Zoete A,van Middelkoop M,Assendelft WJJ,de Boer MR,van Tulder MW
BMJ2019 Mar 13;364:l689.doi: 10.1136/bmj.l689.PMID:30867144Free PMC Article
Bernstein IA,Malik Q,Carville S,Ward S
BMJ2017 Jan 6;356:i6748.doi: 10.1136/bmj.i6748.PMID:28062522
Coulombe BJ,Games KE,Neil ER,Eberman LE
J Athl Train2017 Jan;52(1):71-72.Epub 2016 Nov 16doi: 10.4085/1062-6050-51.11.16.PMID:27849389Free PMC Article
Koes BW,van Tulder MW,Peul WC
BMJ2007 Jun 23;334(7607):1313-7.doi: 10.1136/bmj.39223.428495.BE.PMID:17585160Free PMC Article

Prognosis

Jensen RK,Kongsted A,Kjaer P,Koes B
BMJ2019 Nov 19;367:l6273.doi: 10.1136/bmj.l6273.PMID:31744805
Shiri R,Falah-Hassani K,Heliövaara M,Solovieva S,Amiri S,Lallukka T,Burdorf A,Husgafvel-Pursiainen K,Viikari-Juntura E
Arthritis Care Res (Hoboken)2019 Feb;71(2):290-299.doi: 10.1002/acr.23710.PMID:30044543
Gugliotta M,da Costa BR,Dabis E,Theiler R,Jüni P,Reichenbach S,Landolt H,Hasler P
BMJ Open2016 Dec 21;6(12):e012938.doi: 10.1136/bmjopen-2016-012938.PMID:28003290Free PMC Article
Koes BW,van Tulder MW,Peul WC
BMJ2007 Jun 23;334(7607):1313-7.doi: 10.1136/bmj.39223.428495.BE.PMID:17585160Free PMC Article
Smith L
Clin Orthop Relat Res1969 Nov-Dec;67:72-80.PMID:4243384

Clinical prediction guides

Liu C,Ferreira GE,Abdel Shaheed C,Chen Q,Harris IA,Bailey CS,Peul WC,Koes B,Lin CC
BMJ2023 Apr 19;381:e070730.doi: 10.1136/bmj-2022-070730.PMID:37076169Free PMC Article
Bastos RM,Moya CR,de Vasconcelos RA,Costa LOP
J Man Manip Ther2022 Aug;30(4):207-227.Epub 2022 Jan 24doi: 10.1080/10669817.2021.2024677.PMID:35067217Free PMC Article
Bailey CS,Rasoulinejad P,Taylor D,Sequeira K,Miller T,Watson J,Rosedale R,Bailey SI,Gurr KR,Siddiqi F,Glennie A,Urquhart JC
N Engl J Med2020 Mar 19;382(12):1093-1102.doi: 10.1056/NEJMoa1912658.PMID:32187469
Dower A,Davies MA,Ghahreman A
World Neurosurg2019 Aug;128:114-121.Epub 2019 Apr 25doi: 10.1016/j.wneu.2019.04.147.PMID:31028982
Peul WC,van Houwelingen HC,van den Hout WB,Brand R,Eekhof JA,Tans JT,Thomeer RT,Koes BW;Leiden-The Hague Spine Intervention Prognostic Study Group
N Engl J Med2007 May 31;356(22):2245-56.doi: 10.1056/NEJMoa064039.PMID:17538084

Recent systematic reviews

Liu C,Ferreira GE,Abdel Shaheed C,Chen Q,Harris IA,Bailey CS,Peul WC,Koes B,Lin CC
BMJ2023 Apr 19;381:e070730.doi: 10.1136/bmj-2022-070730.PMID:37076169Free PMC Article
Zaina F,Côté P,Cancelliere C,Di Felice F,Donzelli S,Rauch A,Verville L,Negrini S,Nordin M
Arch Phys Med Rehabil2023 Nov;104(11):1913-1927.Epub 2023 Mar 23doi: 10.1016/j.apmr.2023.02.022.PMID:36963709
Dove L,Jones G,Kelsey LA,Cairns MC,Schmid AB
Eur Spine J2023 Feb;32(2):517-533.Epub 2022 Dec 29doi: 10.1007/s00586-022-07356-y.PMID:36580149Free PMC Article
Bastos RM,Moya CR,de Vasconcelos RA,Costa LOP
J Man Manip Ther2022 Aug;30(4):207-227.Epub 2022 Jan 24doi: 10.1080/10669817.2021.2024677.PMID:35067217Free PMC Article
van der Windt DA,Simons E,Riphagen II,Ammendolia C,Verhagen AP,Laslett M,Devillé W,Deyo RA,Bouter LM,de Vet HC,Aertgeerts B
Cochrane Database Syst Rev2010 Feb 17;(2):CD007431.doi: 10.1002/14651858.CD007431.pub2.PMID:20166095

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See theFAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See theFAQ for details.

    Curated

    • NICE, 2020
      UK NICE Guideline NG59, Low back pain and sciatica in over 16s: assessment and management, 2020

    Consumer resources

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

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