Study could help reveal why some mental health disorders vary between men and women — but it's not clear whether the differences are due to sex or gender.

Preprint repositories and conference organizers are having to counter a tide of ‘AI slop’ submissions.

Astrocytes in the basolateral amygdala dynamically track fear state and support fear memory retrieval and extinction.

AI agents can pay people to complete tasks they aren’t able to do on RentAHuman.ai. Plus, a key US infectious-disease centre plans to scale back pandemic planning and how to better assess scientific understanding among the public.

Instead of trying to refine diagnoses, we should focus on how best to give people the care that they need.

De novo designed proteins that target the transmembrane domain of G-protein-coupled receptors, created using iterative structural predictions, are able to act as agonist-positive, negative or biased allosteric modulators of downstream activity.

Aluminium redox catalysis is achieved with a low-valent aluminium species, carbazolylaluminylene, enabling cyclotrimerization of alkynes and producing diverse benzene derivatives.

An orthosteric CSN inhibitor gains nanomolar potency via a molecular-glue mechanism, stabilizing a CSN5–N8–inhibitor complex that confers substrate-dependent inhibition despite weak free-enzyme affinity.

An outbreak of MPXV in sooty mangabeys in Côte d’Ivoire was linked to MPXV-infected fire-footed rope squirrels, providing direct evidence of interspecies transmission and indicating risk for zoonotic transmission of MPXV from both hosts.