- News & Views
- Published:
G protein—coupled receptors: too many dimers?
Nature Methodsvolume 3, pages972–973 (2006)Cite this article
411Accesses
6Altmetric
A new method for analyzing membrane protein oligomerization by bioluminescence resonance energy transfer (BRET) suggests that dimerization of G protein–coupled receptors (GPCRs) may not be as prevalent as commonly believed.
This is a preview of subscription content,access via your institution
Access options
Subscription info for Japanese customers
We have a dedicated website for our Japanese customers. Please go tonatureasia.com to subscribe to this journal.
Prices may be subject to local taxes which are calculated during checkout

References
James, J.R., Oliveira, M.J., Carmo, A.M., Iaboni, A. & Davis, S.J.Nat. Methods3, 1001–1006 (2006).
Cone, R.A.Nature New Biol.236, 39–43 (1972).
Poo, M. & Cone, R.A.Nature247, 438–441 (1974).
Bulenger, S., Marullo, S. & Bouvier, M.Trends Pharmacol. Sci.26, 131–137 (2005).
Liang, Y . et al.J. Biol. Chem.278, 21655–21662 (2003).
Hlavackova, V . et al.EMBO J.24, 499–509 (2005).
Chabre, M. & le Maire, M.Biochemistry44, 9395–9403 (2005).
Vilardaga, J.P., Bünemann, M., Krasel, C., Castro, M. & Lohse, M.J.Nat. Biotechnol.21, 807–812 (2003).
Author information
Authors and Affiliations
Institute for Pharmacology and Toxicology, University of Würzburg, Germany
Martin J Lohse
- Martin J Lohse
You can also search for this author inPubMed Google Scholar
Rights and permissions
About this article
Cite this article
Lohse, M. G protein—coupled receptors: too many dimers?.Nat Methods3, 972–973 (2006). https://doi.org/10.1038/nmeth1206-972
Issue Date:
Share this article
Anyone you share the following link with will be able to read this content:
Sorry, a shareable link is not currently available for this article.
Provided by the Springer Nature SharedIt content-sharing initiative