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Nature Immunology
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Twenty-first century Foxp3

Nature Immunologyvolume 4, pages304–306 (2003)Cite this article

The transcription factor(s) controlling TReg cell development are not definitely known. The finding that these cells specifically express Foxp3 provides a better understanding of their development and function at the molecular level.

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Figure 1: Equilibrium in the control of effector T cells.

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Acknowledgements

We thank B. Stockinger, R. Marques, P.L. Vieira, D. Robinson, J.P. Pereira and A. Bandeira for helpful comments.

Author information

Authors and Affiliations

  1. Division of Immunoregulation, The National Institute for Medical Research (NIMR), London, NW7 1AA, United Kingdom

    Anne O'Garra

  2. Unité du Développement des Lymphocytes (CNRS URA 1961), Institut Pasteur, 25 Rue du Docteur Roux, Paris, 757015, France

    Paulo Vieira

Authors
  1. Anne O'Garra

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  2. Paulo Vieira

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Corresponding author

Correspondence toAnne O'Garra.

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Associated content

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

  • Jason D. Fontenot
  • Marc A. Gavin
  • Alexander Y. Rudensky
Nature ImmunologyArticle

An essential role for Scurfin in CD4+CD25+ T regulatory cells

  • Roli Khattri
  • Tom Cox
  • Fred Ramsdell
Nature ImmunologyArticle

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