| Entry | |
|---|
| Name | Thiopental sodium (JP18/USP/INN);
Pentothal (TN) |
|---|
| Formula | C11H17N2O2S. Na
|
|---|
| Exact mass | 264.0908
|
|---|
| Mol weight | 264.32
|
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| Structure | 
|
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| Simcomp | |
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| Class | |
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| Remark | | Therapeutic category: | 1115 |
| Product (DG00790): | D00714<JP> |
|
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| Efficacy | Anesthetic (intravenous), Anticonvulsant |
|---|
| Comment | Barbiturates
|
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| Target | |
|---|
| Pathway | | hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Interaction | |
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| Structure map | | map07230 | GABA-A receptor agonists/antagonists |
|
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| Brite | Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N01 ANESTHETICS
N01A ANESTHETICS, GENERAL
N01AF Barbiturates, plain
N01AF03 Thiopental
D00714 Thiopental sodium (JP18/USP/INN) <JP>
N05 PSYCHOLEPTICS
N05C HYPNOTICS AND SEDATIVES
N05CA Barbiturates, plain
N05CA19 Thiopental
D00714 Thiopental sodium (JP18/USP/INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
111 General anesthetics
1115 Barbiturates and thiobarbiturates
D00714 Thiopental sodium (JP18/USP/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01837 Barbiturate sedative-hypnotics
DG00790 Thiopental
D00714 Thiopental sodium
DG01567 GABA-A receptor agonist
DG00790 Thiopental
D00714 Thiopental sodium
DG02030 Anesthetics
DG02027 General anesthetics
DG02025 Barbiturate anesthetics
DG00790 Thiopental
D00714 Thiopental sodium
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
GABA (ionotropic)
GABR
D00714 Thiopental sodium (JP18/USP/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00714 Thiopental sodium
D00714 Thiopental sodium for injection
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01837 Barbiturate sedative-hypnotics
DG00790 Thiopental
DG01567 GABA-A receptor agonist
DG00790 Thiopental
DG02030 Anesthetics
DG02027 General anesthetics
DG02025 Barbiturate anesthetics
DG00790 Thiopental
|
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| Other DBs | |
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| LinkDB | |
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| KCF data |
ATOM 17
1 C1z C 26.2911 -18.1358
2 C5x C 25.0763 -17.4408
3 C5x C 26.2911 -19.5434
4 C1c C 27.6811 -18.1358
5 C1b C 26.2851 -16.7400
6 N1x N 23.8557 -18.1358
7 O5x O 25.0646 -16.0333
8 N2x N 25.0763 -20.2443
9 O5x O 27.4941 -20.2443
10 C1b C 28.3760 -16.9210
11 C1a C 28.6680 -19.1229
12 C1a C 27.4941 -16.0391
13 C2y C 23.8557 -19.5434
14 C1b C 29.7720 -16.9210
15 S1a S 22.6350 -20.2383 #-
16 C1a C 30.4612 -15.7120
17 Z Na 20.3971 -20.2427 #+
BOND 16
1 1 2 1
2 1 3 1
3 1 4 1
4 1 5 1
5 2 6 1
6 2 7 2
7 3 8 1
8 3 9 2
9 4 10 1
10 4 11 1
11 5 12 1
12 6 13 1
13 10 14 1
14 13 15 1
15 14 16 1
16 8 13 2
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