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| - The "laboratory mouse" originated from a mixture ofM. m. domesticus,M. m. musculus, andM. m. molossius subspecies. An inbred strain of the laboratory mouse is defined as a strain that has been brother/sister mated for 20 or more consecutive generations and can be traced to a single ancestral pair. For further information about inbred strains of mice seeStrains, SNPs and Polymorphisms.
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| Mouse Genome Length Estimates | | 2,716,965,481 bp | Reference assembly (C57BL/6J, "golden path") length: the sum of non-redundant top level sequence regions(J:80507). | | 2.5 x 109 bp | Mouse Genome Sequencing Consortium. 2002. Initial sequencing and comparative analysis of the mouse genome. Nature 420: 520-562. | | 1355.5 cM | BSS and BSB crosses: Rowe LB; Barter ME; Kelmenson JA; Eppig J. 2003. Genome Res 13(1):122-33 (J:81431). | | 1450 cM | Copeland, NG, et al. 1993. Science 62:57-66. (J:14384). | | 1360.9 cM | Dietrich, WF et al. 1996. Nature Mar 14:380(6570)149-52 ( J:34212). |
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| Mouse Chromosomal Size | | Chromosome | Mapped Length (cM) | Total Estimated Size (Mbp) (NCBI build GRCm39) |
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| 1 | 98.5 | 195 | | 2 | 103.9 | 182 | | 3 | 82.7 | 160 | | 4 | 88.6 | 157 | | 5 | 90.2 | 152 | | 6 | 79.0 | 150 | | 7 | 89.1 | 145 | | 8 | 76.2 | 130 | | 9 | 75.1 | 124 | | 10 | 77.9 | 131 | | 11 | 88.0 | 122 | | 12 | 63.9 | 120 | | 13 | 67.3 | 121 | | 14 | 66.4 | 125 | | 15 | 59.0 | 104 | | 16 | 57.8 | 98 | | 17 | 61.3 | 95 | | 18 | 59.4 | 91 | | 19 | 56.9 | 61 | | X | | 169 | | Y | | 91 | | MT | | 16299 bp | | Total: | 1441.2 | 2723 |
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| Mouse Physiology | - The estimates below are based on information inBiologyof the Laboratory Mouse (the Staff of The Jackson Laboratory, E. Green, ed. 1966, Dover Publications, New York) and in theMouse Phenome Database (MPD) at The Jackson Laboratory.
- Note: Strain variation can affect these values significantly.
- General
- Body weight: average ~20 g; highly variable
- Mouse Phenome Database:body weight
- Body Temperature: ~36.9 C (in addition to strain, variables are age, sex, environmental conditions)
- Lifespan: 1.3 - 3 years; highly variable
- Reproduction
- Sexual maturity:after ~4 weeks of age; highly variable
- Estrus cycle frequency: every ~4-5 days
- Gestation: Average 19-21 days
- Litter size: usually 1-10 pups - highly variable due to geneticand environmental factors; tends to increase for the first few litters, then decrease with age
- Reproductive lifespan of a female: approaches 2 years in somestrains
- Lactation: duration ~4 weeks
- Mouse Phenome Database:reproduction data
- Circulation
- Total serum protein: ~4-7 g/100 ml
- Blood volume: ~5.5 ml per 100 g body weight
- Heart rate: Adult: 632 +/- 51.3 beats per minute; Newborn: 286 +/- 56.8 beats per minute
- Mouse Phenome Database:cardiovascular
- Systolic pressure: 83-164 mm Hg
- Blood pH: 7.3-7.4
- Mouse Phenome Database:pH,blood chemistry
- Respiration
- Respiratory rate: ~163 per minute
- Mouse Phenome Database:respiratory function
- Tidal volume: ~0.15 ml
- Urinary Tract
- Average urine output: ~1.6 ml per 24 hr
- Average water intake: ~ 5 ml per 24 hr
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