Analysis ToolsMGI collects and annotates expression and activity data for recombinase-containing transgenes and knock-in alleles.
Retrieve a list of all recombinase-containing transgenes and knock-in alleles.
Search for recombinase-containing transgene or knock-in alleles, or floxed or frt alleles using MGI's Allele Query Form
Search for endogenous gene expression using MGI's Gene Expression Data Query Form
How do I...
| Cre is currently the most commonly used recombinase. It catalyzes site-specific recombination of DNA between loxP sites, thus making possible conditional mutagenesis, where specific genes can be knocked out in particular tissues and at particular developmental time points. Other non-cre recombinases (such as Flp, Dre, phiC31, etc.) and various inducible forms of recombinases have been and are being developed. We are curating data about all recombinase-containing transgenes and knock-ins developed in mice to provide a comprehensive resource delineating known activity patterns and allowing users to find relevant mouse resources for their studies. |
| Available data will continue to increase. To retrieve all recombinase-containing transgenes and knock-in alleles, use RETRIEVE ALL ALLELES, above. |
| The Recombinase Activity project is funded by NIH grants OD011190 and HD062499. |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) | ||
| Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. | last database update 01/28/2026 MGI 6.24 |  |
