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Glossary Term
Glossary Term Uniparental Disomy
Definition The inheritance, in adiploid organism, of both copies of a singlechromosome from one parent. This may result from the union of agamete bearing two copies of one chromosome with a gamete bearing no copy of that chromosome, or from the union of a gamete bearing two copies of one chromosome with a normal gamete, followed by the loss of one chromosome through an error inmitosis. Because ofimprinting, uniparental disomy can havephenotypic consequences in mammals. See, for example,Prader-Willi Syndrome.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/07/2025
MGI 6.24
The Jackson Laboratory

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