Analysis Tools| Glossary Term | Semidominant |
| Definition | One of a series of terms applied to thephenotypic effect of a particularallele in reference to another allele (usually the standardwild-type allele) with respect to a giventrait. An allele "A" is said to be semidominant with respect to the allele "a" if the A/Ahomozygote has a mutant phenotype, the A/aheterozygote has a less severe phenotype, while the a/ahomozygote is wild-type. An example isPmp22(Tr-J) in mouse. Pmp22(Tr-J)/Pmp22(Tr-J) animals display a myelination defect associated with a "trembler" phenotype, while Pmp22(Tr-J)/Pmp22(+) animals are less severely affected, and Pmp22(+)/Pmp22(+) animals are wild-type. See also: |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) | ||
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