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☀️ Shiny App: pkr - Noncompartmental analysishttps://asan.shinyapps.io/pkrshiny
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asancpt/pkrshiny
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pkr Shinyhttps://asan.shinyapps.io/pkrshinypkr Shinyis open to everyone. We are happy to take your input. Please fork the repo, modify the codes and submit a pull request.https://github.com/asancpt/pkrshiny- We are actively developing R pacakges, Shiny Apps, and Edison Science Apps regarding clinical pharmacology and pharmacometrics. Please check here.https://asancpt.github.io/softwares
install.packages("pkr")library(pkr)NCA(Theoph,"Subject","Time","conc",dose=320,uConc="mg/L")
pkrpackage helphttps://cran.r-project.org/web/packages/pkr/pkr.pdf
Theoph: Oral 320 mg (N=12)http://stat.ethz.ch/R-manual/R-devel/library/datasets/html/Theoph.htmlIndometh: IV 25 mg (N=6)http://stat.ethz.ch/R-manual/R-devel/library/datasets/html/Indometh.htmlsd_oral_richpk: Oral 5000mg (N=50)https://github.com/dpastoor/PKPDdatasetssd_iv_rich_pkpd: IV diverse dosing (N=60)https://github.com/dpastoor/PKPDdatasets
Gabrielsson J, Weiner D. Pharmacokinetic and Pharmacodynamic Data Analysis - Concepts and Applications. 5th ed. 2016.
Shargel L, Yu A. Applied Biopharmaceutics and Pharmacokinetics. 7th ed. 2015.
Rowland M, Tozer TN. Clinical Pharmacokinetics and Pharmacodynamics - Concepts and Applications. 4th ed. 2011.
Gibaldi M, Perrier D. Pharmacokinetics. 2nd ed. revised and expanded. 1982.
Chang W, Cheng J, Allaire J, Xie Y, McPherson J (2020).shiny: Web Application Framework for R.R package version 1.4.0.1,https://CRAN.R-project.org/package=shiny.
Bae K, Lee JE (2018).pkr: Pharmacokinetics in R.R package version 0.1.2,https://CRAN.R-project.org/package=pkr.
Allaire J, Horner J, Xie Y, Marti V, Porte N (2019).markdown: Render Markdown with the C Library 'Sundown'.R package version 1.1,https://CRAN.R-project.org/package=markdown.
Grosjean P, Ibanez F (2018).pastecs: Package for Analysis of Space-Time Ecological Series.R package version 1.3.21,https://CRAN.R-project.org/package=pastecs.
Wickham H (2016).ggplot2: Elegant Graphics for Data Analysis.Springer-Verlag New York.ISBN 978-3-319-24277-4,https://ggplot2.tidyverse.org.
Wickham H, François R, Henry L, Müller K (2020).dplyr: A Grammar of Data Manipulation.https://dplyr.tidyverse.org,https://github.com/tidyverse/dplyr.
Wickham H, Henry L (2020).tidyr: Tidy Messy Data.R package version 1.0.2,https://CRAN.R-project.org/package=tidyr.
Gohel D, Skintzos P (2019).ggiraph: Make 'ggplot2' Graphics Interactive.R package version 0.7.0,https://CRAN.R-project.org/package=ggiraph.
Chang W, Borges Ribeiro B (2018).shinydashboard: Create Dashboards with 'Shiny'.R package version 0.7.1,https://CRAN.R-project.org/package=shinydashboard.
Xie Y (2020).knitr: A General-Purpose Package for Dynamic Report Generation in R.R package version 1.28,https://yihui.org/knitr/.
Xie Y (2015).Dynamic Documents with R and knitr, 2nd edition.Chapman and Hall/CRC, Boca Raton, Florida.ISBN 978-1498716963,https://yihui.org/knitr/.
Xie Y (2014).“knitr: A Comprehensive Tool for Reproducible Research in R.”In Stodden V, Leisch F, Peng RD (eds.),Implementing Reproducible Computational Research.Chapman and Hall/CRC.ISBN 978-1466561595,http://www.crcpress.com/product/isbn/9781466561595.
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☀️ Shiny App: pkr - Noncompartmental analysishttps://asan.shinyapps.io/pkrshiny