PDBsum entry 1nf3

		Signaling protein

194 a.a.* 123 a.a.* GNP _MG  ×423 * Residue conservation analysis

PDB id: Links PDBe RCSB MMDB JenaLib Proteopedia CATH SCOP PDBSWS PDBbind PDBePISA CSA ProSAT Name: Title: Structure of cdc42 in a complex with the gtpase-binding domain of the cell polarity protein, par6 Structure: G25k gtp-binding protein, placental isoform. Chain: a, b. Synonym: gp, cdc42 homolog. Engineered: yes. Mutation: yes. Par-6b. Chain: c, d. Fragment: gtpase-binding domain. Engineered: yes Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cdc42. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Mus musculus. House mouse. Organism_taxid: 10090. Biol. unit: Tetramer (fromPQS) Resolution: 2.10Å     R-factor:   0.219     R-free:   0.273 Authors: S.M.Garrard,C.T.Capaldo,L.Gao,M.K.Rosen,I.G.Macara,D.R.Tomchick Key ref: S.M.Garrardet al. (2003). Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6.EMBO J,22, 1125-1133. Date: 12-Dec-02     Release date:   04-Mar-03      Headers  References Protein chains   ?  (CDC42_HUMAN) -  Cell division control protein 42 homolog from Homo sapiens Protein chains   ?  (PAR6B_MOUSE) -  Partitioning defective 6 homolog beta from Mus musculus

	Enzyme class:		Chains A, B:E.C.3.6.5.2	[IntEnz]  [ExPASy]  [KEGG]  [BRENDA]
	Reaction:
	GTP H2O GDP phosphate H(+)

		DOI no: 10.1093/emboj/cdg110 EMBO J22:1125-1133 (2003) PubMed id: 12606577           ABSTRACT       21557504 (2011).   Dev Neurobiol,71, 528-553.   21342553 (2011).   BMC Bioinformatics,12, S23.     20052683 (2010).   Protein Sci,19, 398-411.   20122916 (2010).   Dev Biol,340, 88-98.   20062059 (2010).   Nat Struct Mol Biol,17, 180-186. 3a58 20493700 (2010).   Curr Biol,20, 1065-1074.   20533885 (2010).   Annu Rev Biochem,79, 707-735.   20479467 (2010).   J Cell Biol,189, 661-669.   19064640 (2009).   Mol Cell Biol,29, 1035-1049.   19815182 (2009).   Int Rev Cell Mol Biol,278, 309-353.     20066082 (2009).   Cold Spring Harbor Perspect Biol,1, a001370.   19542980 (2009).   Curr Opin Nephrol Hypertens,18, 324-330.   19279126 (2009).   J Am Soc Nephrol,20, 798-806.   19394299 (2009).   Mol Cell,34, 223-233. 2w2t2w2v2w2w2w2x 18074341 (2008).   J Comput Chem,29, 1131-1141.   18817769 (2008).   Dev Biol,324, 41-54.   18946477 (2008).   Nat Rev Mol Cell Biol,9, 887-901.   18927392 (2008).   Science,322, 438-442.   18365233 (2008).   Histochem Cell Biol,130, 1.   18348980 (2008).   J Biol Chem,283, 14153-14164. 2qrz 19029931 (2008).   Oncogene,27, 6878-6887.   17981131 (2007).   Dev Cell,13, 609-622.   17420281 (2007).   Mol Cell Biol,27, 4431-4443.   17110935 (2007).   J Invest Dermatol,127, 782-791.   17914350 (2007).   Kidney Int,72, 1448-1458.   17726059 (2007).   J Cell Sci,120, 3200-3206.   17154294 (2007).   Mol Reprod Dev,74, 785-794.   16650994 (2006).   Trends Cell Biol,16, 308-316.   16678097 (2006).   Cell,125, 535-548.   16949360 (2006).   Mol Cell,23, 631-640.   16771626 (2006).   Annu Rev Cell Dev Biol,22, 207-235.   17115053 (2006).   Nat Struct Mol Biol,13, 1135-1140. 2fju 16405658 (2006).   Immunol Cell Biol,84, 107-113.   15666355 (2005).   Bioessays,27, 126-135.   15548602 (2005).   Mol Biol Cell,16, 871-880.   14752106 (2004).   J Biol Chem,279, 14929-14936.   15173827 (2004).   Nat Rev Mol Cell Biol,5, 481-492.   15023337 (2004).   Mol Cell,13, 665-676. 1ry41rzx 14991002 (2004).   Nat Rev Mol Cell Biol,5, 220-231.   15367757 (2004).   Sci STKE,2004, RE13.   15663004 (2004).   Mol Biol Rep,31, 203-215.   15292221 (2004).   J Biol Chem,279, 41557-41562.   15140881 (2004).   J Biol Chem,279, 30715-30721.   15577926 (2004).   EMBO Rep,5, 1130-1136.   15353546 (2004).   J Cell Biol,166, 889-900.   14685273 (2004).   EMBO J,23, 77-88.   14530286 (2003).   J Biol Chem,278, 51885-51893.   12956948 (2003).   Curr Biol,13, 1469-1479.   The most recent references are shown first. Citation data come partly fromCiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time. Where a reference describes a PDB structure, the PDB code is shown on the right.   [8]ページ先頭 ©2009-2025 Movatter.jp