PDBsum entry 1ihj

		Signaling protein

94 a.a.* THR-GLU-PHE-CYS- ALA  ×172 * Residue conservation analysis

PDB id: Links PDBe RCSB MMDB JenaLib Proteopedia CATH SCOP PDBSWS PDBePISA ProSAT Name: Title: Crystal structure of the n-terminal pdz domain of inad in complex with a norpa c-terminal peptide Structure: Inad. Chain: a, b. Fragment: pdz1 domain. Engineered: yes. PhospholipasE C. Chain: c, d. Fragment: c-terminus. Synonym: norpa. Engineered: yes Source: Drosophila melanogaster. Fruit fly. Organism_taxid: 7227. Gene: inad. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Other_details: this peptide was chemically synthesized. It consists of the final seven residues of phospholipasE C (gktefca). Biol. unit: Dimer (fromPQS) Resolution: 1.80Å     R-factor:   0.220     R-free:   0.240 Authors: M.E.Kimple,D.P.Siderovski,J.Sondek Key ref: M.E.Kimpleet al. (2001). Functional relevance of the disulfide-linked complex of the N-terminal PDZ domain of InaD with NorpA.EMBO J,20, 4414-4422. Date: 19-Apr-01     Release date:   22-Aug-01      Headers  References Protein chains   ?  (INAD_DROME) -  Inactivation-no-after-potential D protein from Drosophila melanogaster

	Enzyme class:		E.C.3.1.4.3	[IntEnz]  [ExPASy]  [KEGG]  [BRENDA]
	Reaction:
	1,2-diacyl-sn-glycero-3-phosphocholine H2O phosphocholine 1,2- diacyl-sn-glycerol H(+)
	Cofactor:

		DOI no: 10.1093/emboj/20.16.4414 EMBO J20:4414-4422 (2001) PubMed id: 11500369           ABSTRACT     20509869 (2010).   Cell Commun Signal,8, 8.   20026484 (2010).   Mol Biol Evol,27, 1058-1069.   18184564 (2008).   Neuron,57, 56-68.   17227205 (2007).   J Bone Miner Res,22, 609-616.   17277057 (2007).   J Bacteriol,189, 3176-3186.   17923089 (2007).   Cell,131, 80-92. 2qkt2qku2qkv 16741958 (2006).   Proteins,64, 804-807. 2ev8 17002371 (2006).   J Am Chem Soc,128, 12766-12777.   15978037 (2005).   FEBS J,272, 3306-3316.   12592016 (2003).   Protein Sci,12, 458-467.   12954649 (2003).   J Biol Chem,278, 48099-48104. 1q3o1q3p 12493751 (2003).   J Biol Chem,278, 8501-8507. 1n7e1n7f 11741967 (2002).   J Biol Chem,277, 5699-5702.   11882663 (2002).   J Biol Chem,277, 18973-18978. 1gq41gq5 The most recent references are shown first. Citation data come partly fromCiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time. Where a reference describes a PDB structure, the PDB codes are shown on the right.   [8]ページ先頭 ©2009-2025 Movatter.jp