PDBsum entry 1dzg

		Blood clotting

422 a.a.* NAG-NAG NAG GOL  ×4 * Residue conservation analysis

PDB id: Links PDBe RCSB MMDB JenaLib Proteopedia CATH SCOP PDBSWS PDBePISA ProSAT Name: Title: N135q-s380c-antithrombin-iii Structure: Antithrombin-iii. Chain: i. Synonym: atiii, serpin c1. Engineered: yes. Mutation: yes. Other_details: inhibitory conformation. Antithrombin-iii. Chain: l. Synonym: atiii, serpin c1. Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: cricetidae sp.. Expression_system_taxid: 36483. Other_details: recombinant. Baby hamster kidney (bhk) cell expression. Other_details: plasma alpha antithrombin-iii Biol. unit: Monomer (from PDB file) Resolution: 2.80Å     R-factor:   0.228     R-free:   0.297 Authors: A.J.Mccoy,J.A.Huntington,R.W.Carrell Key ref: J.A.Huntingtonet al. (2000). The conformational activation of antithrombin. A 2.85-A structure of a fluorescein derivative reveals an electrostatic link between the hinge and heparin binding regions.J Biol Chem,275, 15377-15383. Date: 28-Feb-00     Release date:   26-May-00      Headers  References Protein chains  (ANT3_HUMAN) -  Antithrombin-III from Homo sapiens

		DOI no: 10.1074/jbc.275.20.15377 J Biol Chem275:15377-15383 (2000) PubMed id: 10809774           ABSTRACT       20024502 (2010).   Thromb Haemost,103, 277-283.   20184328 (2010).   Biochemistry,49, 2680-2686.   19668868 (2009).   Mol Biosyst,5, 1025-1031.   19715676 (2009).   Biochem Biophys Res Commun,389, 162-167.   19401470 (2009).   J Biol Chem,284, 20441-20445.   18647228 (2008).   J Thromb Haemost,6, 1697-1706.   16618121 (2006).   Biochemistry,45, 5324-5329.     17114499 (2006).   J Immunol,177, 8219-8225.   17319097 (2005).   Vasc Health Risk Manag,1, 41-53.   15782418 (2005).   Pediatr Blood Cancer,45, 741-752.   15311268 (2004).   Nat Struct Mol Biol,11, 863-867. 1sr5 14705167 (2004).   Med Res Rev,24, 151-181.   12022882 (2002).   Biochemistry,41, 6780-6788.   The most recent references are shown first. Citation data come partly fromCiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time. Where a reference describes a PDB structure, the PDB code is shown on the right.   [8]ページ先頭 ©2009-2025 Movatter.jp