›8ezd

Electron Microscopy
2.83Å resolution

Brain-derived 42-residue amyloid-beta fibril type A

Released:
PDB entry 8ezd coloured by chain, ensemble of 9 models, front view.
PDB entry 8ezd coloured by chain, ensemble of 9 models, side view.
PDB entry 8ezd coloured by chain, ensemble of 9 models, top view.

Function and BiologyDetails

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:

Structure analysisDetails

Assembly composition:
homo octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138403 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Amyloid-beta protein 42Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 42 amino acids
Theoretical weight: 4.52 KDa
Source organism:Homo sapiens
Expression system:Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P05067 (Residues: 672-713; Coverage: 6%)
Gene names:A4,AD1,APP
Sequence domains:Beta-amyloid peptide (beta-APP)

Ligands and Environments

No bound ligands
No modified residues

Experiments and ValidationDetails

Entry percentile scores
Resolution: 2.83Å
Relevant EMDB volumes:EMD-28740
Expression system:Escherichia coli BL21(DE3)