›7y8q

Solid-state NMR

Amyloid-beta assemblage on GM1-containing membranes

Released:
PDB entry 7y8q coloured by chain, ensemble of 10 models, front view.
PDB entry 7y8q coloured by chain, ensemble of 10 models, side view.
PDB entry 7y8q coloured by chain, ensemble of 10 models, top view.

Function and BiologyDetails

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:

Structure analysisDetails

Assembly composition:
homo octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138403 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Amyloid-beta protein 40Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 40 amino acids
Theoretical weight: 4.34 KDa
Source organism:Homo sapiens
Expression system:Escherichia coli
UniProt:
  • Canonical: P05067 (Residues: 672-711; Coverage: 5%)
Gene names:A4,AD1,APP
Sequence domains:Beta-amyloid peptide (beta-APP)

Ligands and Environments

No bound ligands
No modified residues

Experiments and ValidationDetails

Entry percentile scores
Chemical shift assignment: 4%
Refinement method: molecular dynamics
Expression system:Escherichia coli