›7ow1

X-ray diffraction
1.4Å resolution

Crystal Structure of TAP01 in complex with amyloid beta peptide

Released:
PDB entry 7ow1 coloured by chain, front view.
PDB entry 7ow1 coloured by chain, side view.
PDB entry 7ow1 coloured by chain, top view.

Function and BiologyDetails

Structure analysisDetails

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-279521 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Amyloid-beta protein 40Chain: A
Molecule details ›
Chain: A
Length: 12 amino acids
Theoretical weight: 1.5 KDa
Source organism:Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P05067 (Residues: 674-685; Coverage: 2%)
Gene names:A4,AD1,APP
TAP01 family antibody heavy chainChain: H
Molecule details ›
Chain: H
Length: 219 amino acids
Theoretical weight: 23.28 KDa
Source organism:Homo sapiens
Expression system:Homo sapiens
    TAP01 family antibody light chainChain: K
    Molecule details ›
    Chain: K
    Length: 214 amino acids
    Theoretical weight: 23.48 KDa
    Source organism:Homo sapiens
    Expression system:Homo sapiens

      Ligands and Environments

      1 bound ligand:
      1 modified residue:

      Experiments and ValidationDetails

      Entry percentile scores
      X-ray source:ESRF BEAMLINE ID30B
      Spacegroup:P41212
      Unit cell:
      a: 71.179Å b: 71.179Å c: 173.37Å
      α: 90° β: 90° γ: 90°
      R-values:
      RR workR free
      0.154 0.152 0.2
      Expression systems:
      • Not provided
      • Homo sapiens

      PDB-REDO

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