›2y3k

X-ray diffraction
1.9Å resolution

Structure of segment MVGGVVIA from the amyloid-beta peptide (Ab, residues 35-42), alternate polymorph 1

Released:
PDB entry 2y3k coloured by chain, front view.
PDB entry 2y3k coloured by chain, side view.
PDB entry 2y3k coloured by chain, top view.
Source organism:Homo sapiens

Function and BiologyDetails

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysisDetails

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-138395 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
P3(40)Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 8 amino acids
Theoretical weight: 745 Da
Source organism:Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P05067 (Residues: 706-713; Coverage: 1%)
Gene names:A4,AD1,APP

Ligands and Environments

No bound ligands
No modified residues

Experiments and ValidationDetails

Entry percentile scores
X-ray source:APS BEAMLINE 24-ID-E
Spacegroup:P1
Unit cell:
a: 9.47Å b: 20.28Å c: 47.69Å
α: 90.21° β: 89.78° γ: 103.55°
R-values:
RR workR free
0.214 0.214 0.231
Expression system: Not provided

Quick links

Citations

40 review citations

8 mentions without citation

Functional Amyloids.
Otzen et al. (2019)
7 more

PDB-REDO

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