Matrix Metalloproteinase Inhibitors

All categories
Name
Matrix Metalloproteinase Inhibitors
Accession Number
DBCAT001461
Description

Compounds that inhibit the enzyme activity or activation of MATRIX METALLOPROTEINASES.

Drugs
DrugDrug Description
2-[3-(5-Mercapto-[1,3,4]thiadiazol-2-yl)-ureido]-N-methyl-3-phenyl-propionamideNot Available
2-[3-(5-Mercapto-[1,3,4]thiadiazol-2yl)-ureido]-N-methyl-3-pentafluorophenyl-propionamideNot Available
AbametapirA pediculicide metalloproteinase used topically in the treatment of head lice infection.
CGS-27023Not Available
IlomastatIlomastat is a broad-spectrum matrix metalloproteinase inhibitor.
PrinomastatInvestigated for use/treatment in brain cancer, lung cancer, and prostate cancer.
S-3304S-3304 has been used in trials studying the treatment of Lung Cancer, Solid Tumors, Non Small Cell Lung Cancer, Stage IIIB Non Small Cell Lung Cancer, and Stage IIIA Non...
Drugs & Drug Targets
DrugTargetType
2-[3-(5-Mercapto-[1,3,4]thiadiazol-2-yl)-ureido]-N-methyl-3-phenyl-propionamideStromelysin-1target
2-[3-(5-Mercapto-[1,3,4]thiadiazol-2-yl)-ureido]-N-methyl-3-phenyl-propionamide72 kDa type IV collagenasetarget
2-[3-(5-Mercapto-[1,3,4]thiadiazol-2yl)-ureido]-N-methyl-3-pentafluorophenyl-propionamideStromelysin-1target
AbametapirCytochrome P450 1A2enzyme
AbametapirCytochrome P450 3A4enzyme
AbametapirCytochrome P450 2B6enzyme
CGS-27023Macrophage metalloelastasetarget
CGS-27023Interstitial collagenasetarget
CGS-27023Neutrophil collagenasetarget
CGS-27023Carbonic anhydrase 9target
CGS-27023Matrix metalloproteinase-9target
CGS-27023Matrilysintarget
CGS-27023A disintegrin and metalloproteinase with thrombospondin motifs 4target
CGS-2702372 kDa type IV collagenasetarget
CGS-27023Matrix metalloproteinase-14target
CGS-27023Carbonic anhydrase 2target
CGS-27023Collagenase 3target
CGS-27023Lethal factortarget
CGS-27023Stromelysin-1target
IlomastatLethal factortarget
IlomastatDisintegrin and metalloproteinase domain-containing protein 28target
IlomastatAggrecan core proteintarget
IlomastatInterstitial collagenasetarget
IlomastatMatrix metalloproteinase-14target
IlomastatNeutrophil collagenasetarget
Ilomastat72 kDa type IV collagenasetarget
IlomastatStromelysin-1target
IlomastatMatrix metalloproteinase-9target
IlomastatMacrophage metalloelastasetarget
IlomastatCollagenase 3target
Prinomastat72 kDa type IV collagenasetarget
PrinomastatInterstitial collagenasetarget
PrinomastatMatrilysintarget